Robot-assisted transperitoneal and retroperitoneal adrenalectomy for huge adrenal tumors in 45 cases / 现代泌尿外科杂志

【Objective】 To compare the outcomes of robot-assisted laparoscopic transperitoneal and retroperitoneal operation for huge (>6 cm) adrenal tumors. 【Methods】 The clinical data of 45 patients with huge adrenal tumors who underwent robotic surgery during Jan.2017 and Dec.2021 were retrospectively analyzed, including 28 cases via the transperitoneal approach and 17 cases via the retroperitoneal approach. 【Results】 No patients were converted to open operations. There were no significant differences in postoperative drainage time (2.24±0.44 vs. 2.36±0.49) d, operation time (130.88±5.96 vs. 136.61±8.39) min, blood loss (189.41±13.91 vs. 192.5±12.36) mL and postoperative hospital stay (7.06±0.56 vs. 7.46±0.69) d between the retroperitoneal and transperitoneal approaches. Retroperitoneal approach was better than transperitoneal approach in early postoperative feeding [(38.82±6.75 vs. 74.14±6.57) h, P<0.01] . 【Conclusion】 Robotic surgery is safe and effective in the treatment of large adrenal tumors. The choice of surgical approach should be based on patients’ condition, tumor volume and location.

The efficacy and safety comparison of transperitoneal laparoscopic adrenalectomy and retroperitoneal laparoscopic adrenalectomy for adrenocortical carcinoma / 中华泌尿外科杂志

Objective:To compare the efficacy and safety of retroperitoneal laparoscopic adrenalectomy (RLA) and transperitoneal laparoscopic adrenalectomy (TLA) in the treatment of localized adrenocortical carcinoma (ACC).Methods:The data of 22 patients with stage Ⅰ/Ⅱ ACC underwent laparoscopic adrenalectomy in our institution from January 2009 to December 2018 were retrospectively analyzed. According to the different surgical approaches, these patients were divided into RLA and TLA groups. Eleven patients underwent RLA and 11 patients underwent TLA. There were no significant differences between the RLA group and the TLA group in terms of age at first diagnosis[44 (35, 54) vs. 46(41, 55) years, P= 0.793], sex (male/female: 3/8 vs. 4/7, P = 1.00), secreting tumor ratio (3/11 vs. 4/11, P = 1.00), tumor location (left/right: 6/6 vs. 7/4, P = 1.00), with hypertension or diabetes mellitus (4/11 vs. 3/11, P = 1.00). However, RLA has significantly smaller tumor size [3.0(2.5, 8.4) cm vs. 7.7(5.2, 8.4)cm, P= 0.001], and more stage Ⅰ patients [90.9%(10/11) vs. 18.2%(2/11), P=0.002], compared with those in TLA group. The perioperative indicators and oncology prognosis outcomes were collected and compared between the two groups. The Kaplan-Meier method was performed to calculate the overall survival (OS) and disease-free survival (DFS). Results:Compared with TLA, RLA had shorter operation time[90(70, 100) vs. 110 (90, 120) min, P = 0.005] and postoperative drainage tube removal time [2 (2, 3) vs. 3 (2, 6) day, P = 0.002), and the difference was statistically significant. In the TLA group, one patient was converted to open operation due to intraoperative tumor capsule rupture. For postoperative complications, one patient in the TLA group suffered with wound infection. There were no perioperative deaths in either group. All postoperative pathological examinations confirmed ACC, and there was no significant difference in Ki-67 index between the two groups [10%(3%, 35%) vs. 10%(9%, 25%), P = 0.484]. The median follow-up was similar in the two groups [48(26, 98) vs. 31(18, 49) months, P=0.237]. The local recurrence and metastasis rates were 36.4% for RLA group and 63.6% for TLA group ( P = 0.395). Survival analysis showed no statistically significant difference in DFS [5-year DFS rate: 33.6% vs. 73.2%, P = 0.118] between the two groups. The 5-year OS rates for RLA group versus TLA group were 58.3% vs. 45.5% ( P=0.485). Conclusions:For localized (stage Ⅰ/Ⅱ) ACC, both RLA and TLA seem safe and feasible, based on the similar long-term oncological prognosis. However, compared with TLA, RLA has the advantage of shorter operation time and postoperative drainage tube removal time. Due to the small number of cases included in this study, further multi-center, large-sample studies are required to demonstrate clear benefit of one surgical approach in the future.

Laparoscopic partial nephrectomy via combined “trans-retro-peritoneal three-step” approach: An initial experience / 第二军医大学学报

Objective To evaluate the safety and efficacy of laparoscopic partial nephrectomy via a combined "trans-retro-peritoneal three-step" approach. Methods The clinical data of 32 patients who received laparoscopic partial nephrectomy between Jul. 2015 and Nov. 2015 were retrospectively analyzed. Twenty cases were via the traditional transperitoneal approach and the other 12 cases via a novel combined "trans-retro-peritoneal three-step" approach. The 3 steps in this novel approach included: (1) Through transperitoneal approach, Gerota's fascia and perirenal fat were incised to expose the tumor; (2) The peritoneum and Gerota's fascia were incised along the Told's line, and the renal artery was then separated on the surface of the psoas muscle; and (3) The renal artery was clamped, the edge of the tumor was marked, and finally the tumor was resected and the kidney was reconstructed. The perioperative data of the two groups were compared. Results The surgeries were successfully performed in all the 32 patients. Compared to traditional transperitoneal approach, our novel approach significantly shortened the operation time (P=0.014). The other perioperative parameters, such as estimated blood loss, were comparable in the two groups. Conclusion This combined "trans-retro-peritoneal three-step" approach has the combined the advantage of traditional transperitoneal (enough room for manipulation) and retroperitoneal (convenience to separate the renal arteries) approaches, especially when the renal artery is abnormal. Further studies are needed to compare the present approach with the traditional surgeries.

Laparoscopic Adrenalectomy in Urology

Laparoscopic adrenalectomy has been the standard method for resecting adrenal gland tumors. Recently, laparoscopic retroperitoneal adrenalectomy (RA) has been more popular than conventional transperitoneal laparoscopic adrenalectomy (TLA) as an alternative method. Studies comparing laparoscopic RA and TLA showed that laparoscopic RA was superior or at least comparable to TLA in operation time, blood loss, pain score, hospital stay, and return to normal activity. Conversion rates and complication rates were similar. At present, laparoscopic RA has been int the limelight procedure for patients with benign adrenal disease. However, surgeons have been reluctant to offer this operation to patients because of the concerns over inadequate working space and overall perceived higher rate of complications, laparoscopic RA is not popular in urologic field up to now. This article summarizes the latest ideas and issues on laparoscopic RA in the expanding field of laparoscopy in urology.

A Case of Surgically Treated by Transperitoneal Approach in Delayed Neurological Deficit after Sacral Fracture: A Case Report

This study reviews a case of sacral fracture with delayed onset neurological deficit that showed good results after decompressive surgery. The delayed neurological deficit appeared at 4 weeks after injury and it was treated with anterior decompression through transperitoneal approach. A 23-year-old woman was injured in a car accident and had bilateral pubic rami fractures and fractures of the sacral ala on the right side. She was treated with external fixation devices for approximately four weeks, but complained of pain and numbness. The dorsiflexion and plantalflexion of the right ankle was weakened and graded as grade 2. Preoperative pelvic and sacral radiographs, computed tomography, magnetic resonance imaging and electromyelography, and nerve conduction study were performed to identify the region of neurological deficit, and we decided to implement neurological decompression. By transperitoneal approach, we performed bone curratage and decompression around the region of sacral alar slope and S1 foramen. The pain and numbness of the right foot cleared up. Dorsiflexion and plantalflexion of the right ankle improved to grade 5. Anterior decompression by transperitoneal approach proved to bring satisfactory results in a patient, who presented delayed neurological deficit after sacral fracture.

Laparoscopic Adrenalectomy: Lessons Learned from 111 Consecutive Cases / 대한내분비외과학회지

PURPOSE: Laparoscopic adrenalectomy has become the standard of care for a variety of benign adrenal pathologies. A total of 111 consecutive adrenalectomies were performed using a lateral transperitoneal or posterior retroperitoneal approach, each with its own inherent benefits and shortcomings. The authors compared the effectiveness and safety of posterior retroperitoneal adrenalectomy (PRA) with that of lateral transperitoneal adrenalectomy (LTA). METHODS: Medical records of 111 patients diagnosed with adrenal tumor who underwent laparoscopic adrenalectomy from January 2000 through April 2012 at Chungnam National Hospital were reviewed retrospectively. Study variables included operative time, length of hospital stay, number of days of pain control, diet beginning and advance, and complications. RESULTS: PRA was shorter in most variables, including operative time, hospital stay, first diet beginning, and full diet advance time compared with that of LTA. In pheochromocytoma less than or equal to 7 cm in size, operation time for LTA was longer than that of PRA. One PRA-specific complication was pseudo-hernia of the ipsilateral abdominal wall, which was resolved spontaneously within 1~2 months. CONCLUSION: Laparoscopic adrenalectomy is a safe and effective approach to benign adrenal pathology, and PRA should be considered in patients with tumors less than or equal to 7 cm.

Modified transperitoneal laparoscopic radical prostatectomy : clinical study of 285 cases / 中华泌尿外科杂志

Objective　To evaluate the technique and clinical outcomes of modified transperitoneal laparoscopic radical prostatectomy.　Methods　A total of 285 patients received the operation with mean age of 67 years (50-76 years) from January 2008 to April 2012.Mean level of PSA was 15.7 μg/L (1.8 -50.0 μg/L),and mean prostatic volume was 44 ml (26 -74 ml). No lymph node or seminal vesicle involvement was found by CT or MR and radionuclide bone scan revealed no metastasis.271 cases were confirmed diagnosis by prostatic biopsy and 14 were detected through pathological studies of TURP specimens.Gleason score ranged from 6 to 8.14 cases were in clinical stage T1b,29 cases in T1c,214 cases in T2 and 28 cases in T3a.Transperitoneal approach and modified technique involving bladder neck dissection,nervesparing technique and vesicoureteral anastomosis were applied on patients.　Results　Mean operative time was 105 min (55 -150 min).Mean intraoperative estimated blood loss was 240 ml (50-800 ml).Rectal injures occurred in 2 cases and were repaired under laparoscopy.Drainage tube and urinary catheter were removed 48 -72 h and 5 -8 d postoperatively.Postoperative hospital stay was 7 d (5 - 11 d).Positive surgical margin was present in 58 patients.Mean follow-up time was 29 months (3 -50 months).Complete continence were found in 208 patients immediately after catheter removal.68 patient recovered continence within 3 months and 9 patients remained incontinence 3 months after surgery. Normal erection presented in 42 of the 57 cases with nerve-sparing.　Conclusions　Transperitoneal laparoscopic radical prostatectomy is safe and efficient.Higher efficiency and lower complication rate have been achieved through modified laparoscopic technique involving bladder neck dissection,nerve-sparing technique and vesicoureteral anastomosis.

Transperitoneal versus retroperitoneal laparoscopic radical nephrectomy: A comparison of clinical outcomes / 第二军医大学学报

To compare clinical outcomes of transperitoneal and retroperitoneal laparoscopic radical nephrectomy for renal cell carcinoma (RCC) and to identify the indicators for each approach. Methods A total of 258 patients underwent transperitoneal(n=116) or retroperitoneal (n=142) laparoscopic radical nephrectomy for RCC. The operation time, blood loss during operation, fasting period after surgery and hospital stay were compared between the two groups. Results The operation time was 80-315 min(a mean of [167±66.8] min) for transperitoneal approach and 85-280 min(a mean of [152± 48.8] min) for retroperitoneal approach (P=0.034). The blood loss was 50-1,000 ml (a mean of [181±140.4] ml) for transperitoneal approach and 50-800 ml(a mean of [171±132.9] ml) for retroperitoneal approach(P=0.544). The fasting period of surgery was 1-5 d (a mean of [2.8±1.3] d) for transperitoneal approach and 1-5 d (a mean of [2.9±1.2] d) for retroperitoneal approach(P=0.801). The hospital stay was 3-9 d (a mean of [6.6±1.5] d) for transperitoneal approach and 3-8 d (a mean of [6.5±1.6] d) for retroperitoneal approach(P = 0. 477). Conclusion Transperitoneal and retroperitoneal approaches both can yield satisfactory surgical outcomes in laparoscopic radical nephrectomy. The transperitoneal approach is suitable for tumors with a larger size.

Transperitoneal versus retroperitoneal laparoscopic radical nephrectomy: A comparison of clinical outcomes / 第二军医大学学报

Objective To compare clinical outcomes of transperitoneal and retroperitoneal laparoscopic radical nephrectomy for renal cell carcinoma (RCC) and to identify the indicators for each approach. Methods A total of 258 patients underwent transperitoneal (n = 116) or retroperitoneal (n = 142) laparoscopic radical nephrectomy for RCC. The operation time, blood loss during operation, fasting period after surgery and hospital stay were compared between the two groups. Results The operation timewas 80-315 min (a mean of [167 ±66. 8] min) for transperitoneal approach and 85-280 min (a mean of [152± 48.8] min) for retroperitoneal approach (P = 0. 034). The blood loss was 50-1,000 ml (a mean of [181±140. 4] ml) for transperitoneal approach and 50-800 ml (a mean of [171 ± 132. 9] ml) for retroperitoneal approach(P = 0. 544). The fasting period of surgery was 1-5 d (a mean of [2. 8±1. 3] d) for transperitoneal approach and 1-5 d (a mean of [2. 9 ±1. 2] d) for retroperitoneal approach(P = 0. 801). The hospital stay was 3-9 d (a mean of [6. 6±1. 5] d) for transperitoneal approach and 3-8 d (a mean of [6. 5±1. 6] d) for retroperitoneal approach(P = 0. 477). Conclusion Transperitoneal and retroperitoneal approaches both can yield satisfactory surgical outcomes in laparoscopic radical nephrectomy. The transperitoneal approach is suitable for tumors with a larger size.

Laparoscopic Adrenalectomy: A Comparison of Lateral Transperitoneal vs Posterior Retroperitoneal Approach / 대한내시경복강경외과학회지

PURPOSE: Laparoscopic adrenalectomy has become the procedure of choice to remove a wide variety of adrenal tumors. The laparoscopic approaches to the adrenal gland include a lateral (transperitoneal) approach and the posterior (retroperitoneal) approach. The aim of the present study is to compare the clinical outcomes from both methods. METHODS: Between January 2000 and October 2008, we performed 60 laparoscopic adrenalectomies, including 29 posterior retroperitoneal approaches (RLA) and 31 lateral transperitoneal approaches (TLA). RESULTS: Sixty patients were treated for the following conditions: adrenocortical adenoma: 35 patients, pheochromocytoma: 19 patients, organizing hematoma: 2 patients, ganglioneuroma: 2 patients, myelolipoma: 1 patient and adrenal oncocytoma: 1 patient. The average tumor size was 3.2+/-1.4 cm in the TLA patient group and 2.9+/-1.4 cm in the RLA patient group. In the TLA group, the procedures were performed with the patients in the lateral position, and the patients were in the prone position in the RLA group. The average operation time of the RLA group was significantly shorter than that of the TLA group. The RLA group had a shorter postoperative hospital stay, they required less postoperative pain control and they resumed a full diet earlier. Conversion to open surgery was required in five patients (16%) in the TLA group. Complications occurred in five patients of the TLA group and in five patients of the RLA group. No mortality was observed in both groups. CONCLUSION: For experienced surgeons, if the adrenal tumor is less than 6 cm in size, posterior retroperitoneal adrenalectomy may be a safer and faster procedure, so it should be considered as the first choice of operation of benign adrenal tumors.

Laparoscopic Burch Colposuspension (Transperitoneal Approach) / 대한비뇨기과학회지

PURPOSE: The Burch bladder neck suspension is a effective treatment for stress urinary incontinence due to hypermobility. To assess the safety, effectiveness and potential benefits of the transperitoneal laparoscopic Burch colposuspension. MATERIALS AND METHOD: We assessed the short-term result of 15 patients who underwent a laparoscopic Burch colposuspension with transperitoneal approach. All patients had stress incontinence with bladder neck hypermobility and no cystocele and rectocele. The 14 patients had coexisting disorder(uterine myoma 11, ovarian cyst 2, carcinoma in situ 1), so concomitant operation was performed 14 cases(laparoscopic assisted vaginal hysterectomy 12, laparoscopic assisted ovarian cystectomy. RESULTS: In 15 patient who underwent the laparoscopic procedure, continent in 11(73%), improved in 1 (6%) and failed in 3(20%) with mean follow-up of 14 months (range 6-18). The mean operation time was 81 minutes(range 70-120), mean postoperative hospital stay was 4.8 days(range 3-7). CONCLUSIONS: Laparoscopic colposuspension with the transperitoneal approach is a reasonable alternative in treating stress urinary incontinence, especially when the patients have previous properitoneal or lower abdominal surgery or concomitant operation for coexisting disease. Early results are similar to those of open and needle suspension techniques, although longer follow-up is necessary to determine longterm efficiency.

Comparison between Transabdominal and Retroperitoneal Approach for Reconstruction of the Infrarenal Abdominal Aorta

To evaluate the efficacy of the retroperitoneal approach when compared with the transperitoneal approach in elective infrarenal aortoiliac reconstruction, retrospective review of consecutive cases was made with multiple intra-and postoperative parameters. Twenty consecutive cases of infrarenal aortoiliac diseases were performed reconstructive surgery from June 1994 to July 1996 at Department of Surgery, Yeungnam University Hospital. Among these patients, 12 cases underwent aortoiliac reconstruction through the transperitoneal approach(8 cases for infrarenal abdominal aortic occlusion and 4 cases for infrarenal abdominal aneurysm) and 8 cases underwent aortoiliac reconstruction through the retroperitoneal approach (5 cases for infrarenal abdominal aortic occlusion and 3 cases for infrarenal abdominal aortic aneurysm). Both groups had similar associated diseases, such as hypertension, myocardial ischemia and COPD. Intraoperative blood loss was minimal and similar in both groups. The intraoperative crystalloid requirements were not significantly higher for the retroperitoneal approach(4800 ml) than the transperitoneal approach(4400 ml)(p>0.05) and perioperative blood requirements were also similar in both groups. The operation time was not taken significantly longer for the retroperitoneal approach(4.4hr) than the trasperitoneal approach(3.9hr)(p>0.05). Nasogastric intubation and initiation of oral feeding was not significantly prolonged in the transperitoneal group(5 days) when compared with the petroperitoneal group(2.5 days)(p>0.05). Postoperative hospitalization was not considerably prolonged in the transperitoneal approach(19 days) when compared with the retroperitoneal approach(16 days)(p>0.05). There noted significant pulmonary complication in the transperitoneal approach group, whereas wound pain was major complication in the retroperitoneal approach group. These experiences demonstrate that the retroperitoneal approach is a preferable alternative to the transperitoneal route in elective aortoiliac reconstruction.

The Treatment of Tuberculous Spondylitis of the Lumbosacral Junction by Transperitoneal Approach / 대한정형외과학회잡지

A total seven cases of tuberculous spondylitis of the lumbosacral junction were treated by transperitoneal anterior vertebral interbody fusion. The postoperative course was unevenful with minimal complications in all cases. There was no evidence of recurrence of infection, low back pain, or sciatica during follow-up periods of seven to sixty months. The clinical experience gained in this study leads us to conclude that the transperitoneal approach for tuberculous spondylitis of the lumbo-sacral junction is advantageous in that, the lesion is exposed under direct vision, so adequate curettage and the bone graft can be carried out accurately and easily.