RESUMO
Obesity has become a matter of quality to health care administrators. The busy lifestyle of people made them prefer fast food instead of taking healthy food. But the people are not aware that fast food habit converts to the disease like obesity, type 2 diabetes mellitus (T2DM), dyslipoproteinemia etc. This case control study had been carried out in department of Physiology in collaboration of Department of Biochemistry and Medicine, Era's Lucknow Medical College & Hospital, Lucknow to explore status blood sugar fasting (BSF), tumor necrosis factor-α (TNF- α), Insulin by standard spectrophotopmetric kit methods, blood pressure (BP) as well as anthropometric measurements with the help of suitable instruments and equipments in Control group, Obese group and Obese with type 2 diabetic group. Values of all above parameters were found increased in obese group with respect to control group and values of all these parameters were found increase in obese with type 2 Diabetes mellitus group with respect to obese group. Thus it is clear that obesity is risk factor for T2DM, Dyslipoproteinemia and coronary artery disease (CAD).
RESUMO
O cromo na dieta de equinos Mangalarga Marchador pode incrementar seu metabolismo energético, melhorando seu desempenho atlético com redução do estresse. Avaliou-se o efeito da suplementação com cromo sobre a bioquímica sérica e leucometria de equinos Mangalarga Marchador submetidos ao treinamento para concurso de marcha. Foi realizado ensaio com 12 éguas Mangalarga Marchador no delineamento experimental inteiramente ao acaso com três tratamentos 0, 5 e 10 mg/dia de Cromo-metionina com quatro repetições. O experimento foi dividido em duas etapas: a primeira composta por 24 dias de adaptação das éguas à dieta, e a segunda constituída por seis dias, onde os animais foram submetidos a três provas de marcha, com duração de 50 minutos cada, em dias alternados. Avaliou-se as concentrações plasmáticas de glicose e lactato; séricas de triglicerol, insulina e cortisol e a contagem de leucócitos totais. Não houve diferença (P>0,05) entre os tratamentos nos parâmetros avaliados. Após o exercício houve aumento (P<0,05) nas concentrações de lactato, insulina e cortisol e na contagem de leucócitos totais. A suplementação com cromo em equinos Mangalarga Marchador não alterou a via metabólica predominante para geração de energia, o estresse induzido pelo exercício e a resposta imune dos animais durante provas de marcha.
Chromium in the diet of Mangalarga Marchador horses can increase their energy metabolism, improving their athletic performance and reducing stress. The effect of chromium supplementation on serum biochemistry and leukocyte count of Mangalarga Marchador horses submitted to training for marching competitions was assessed. 12 Mangalarga Marchador mares were used in a completely randomized experimental design consisting of three treatments 0, 5 ,and 10 mg/day of chromium-methionine and four replicates per treatment. The research was divided into two stages: first a 24-day phase for adaptation to the diet, and a six-day stage when the animals were submitted to three marching tests, lasting 50 minutes each, on alternate days. The plasma levels of glucose and lactate, serum levels of triglycerol, insulin, and cortisol, and white blood cell count were evaluated. There was no difference (P>0.05) among treatments in any of the parameters evaluated. After exercise, levels of lactate, insulin, and cortisol and white blood cell count increased (P<0.05). The supplementation with chromium in Mangalarga Marchador horses did not alter the predominant pathway for energy generation, the exercise-induced stress, and the immune response of animals during marching tests.