A Case of Trichoblastoma, Tumor of the Follicular Infundibulum, Sebaceoma, and Sebaceous Hyperplasia Arising from Nevus Sebaceus / 대한피부과학회지

Nevus sebaceus is a congenital hamartoma with epidermal, follicular, and apocrine elements. Several skin appendage tumors can evolve secondarily from nevus sebaceus. Two different tumors often develop simultaneously on a nevus sebaceus lesion, but the growth of more than two tumors is rare. Herein, we report a case of four appendage tumors including trichoblastoma, tumor of the follicular infundibulum, sebaceoma, and sebaceous hyperplasia within a single nevus sebaceus lesion on the face of a 76-year-old female.

Tumor of follicular infundibulum: An unsuspected cause of macular hypopigmentation.

We present three cases of a rare eruptive variant of tumor of follicular infundibulum. Two patients presented with hypopigmented macules. The clinical differential diagnoses considered in these two cases were vitiligo, lichen sclerosus et atrophicus, and idiopathic guttate hypomelanosis. In the third case, the lesions were hypopigmented fl at topped maculo-papules diagnosed clinically as verruca plana. In all three cases, the histopathological features of plate like growth of pale keratinocytes connected to the epidermis and peritumoral condensation of elastic fi bers were diagnostic. Although no satisfactory treatment is available, the exclusion of other clinical differential diagnosis particularly vitiligo with its psychosocial implications underscores the importance of skin biopsy.

A Case of Nevus Sebaceus, Accompanied by Syringocystadenoma Papilliferum, a Basal Cell Carcinoma-like Tumor, Sebaceous Epithelioma, Apocrine Adenoma and Tumor of Follicular Infundibulum, with Repair by Subgaleal-periosteal Fixation / 대한피부과학회지

Nevus sebaceus is well-known for its potential to develop both benign and malignant neoplasms of epidermal and adnexal origin. We found 5 tumors including syringocystadenoma papilliferum, a basal cell carcinoma-like tumor, sebaceous epithelioma, a tumor of follicular infundibulum and apocrine adenoma within a single nevus sebaceus lesion in a 37-year-old man. This is a rarely reported case of a nevus sebaceus lesion containing a basal carcinoma-like, trichoblastoma-like skin tumor and tumors of follicular infundibulum. The lesion was treated by wide excision and repaired with subgaleal-periosteal fixation which resulted in good wound healing.

Tumor of Follicular Infundibulum / 대한피부과학회지

Tumor of follicular infundibulum is the term coined by Mehregan and Butler in 1961 for a benign hyperplastic lesion that extends from the follicular infundibulum as an epithelial plate with underlying elastic fiber network. This tumor appears as a slightly elevated keratotic lesion and is characterized histologically by proliferation of follicular sheath epithelium in the form of a thin subepidermal plate. We present a typical case of tumor of follicular infundibulum in the left shoulder area of 74 year-old-man. To the best of our knowledge, this is the first reported case of a solitary tumor of follicular infundibulum in Korea.

A Case of Tumor of Follicular Infundibulum Associated with Nevus Sebaceus / 대한피부과학회지

Tumor of the follicular infundibulum is a rare benign adnexal tumor originating from the infundibular portion of hair follicle and the majority of lesions have been solitary and not recognized clinically before biopsy. A 28-year-old female presented with a bean-sized hairless yellowish plaque on the right upper eyebrow, clinically diagnosed as nevus sebaceus. After complete excision, histopathologic examination of the specimen revealed a focal circumscribed subepidermal tumor roughly parallel to the epidermis, composed of proliferation of pale-staining cells containing diastase-labile PAS(+) glycogen, enclosed by a palisaded basal layer with underlying lesion of nevus sebaceus. Upper dermis directly beneath the tumor had accentuated elastic fiber network outlining the tumor base in the elastic stain.

Tumor of Follicular Infundibulum

We report a case of a tumor of the follicular infundibulum in a 54-year-old woman who had a papule on the medial side of the right upper eyelid for four months. Histopathologic findings were characterized by proliferation of follicular infundibular epithelium in the form of a thin subepidermal plate and small hair follicles in the tumor plate.