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Objective To study the change of kidney injury biochemical index before and after SWL in southeast of Chongqing, and toanalyze the constituents of urinary stones,thus to provide the evidence for the treatment of patients with urinary stones by SWL in southeast of Chongqing.Methods 328 patients with urinary stones form our hospital in Southeast of Chongqing during 2008 to 2014 underwent SWL were enrolled.And we detected the levels of urine mALB,serum β2-MG,BUN,Cr before and after operation.The results were statistically analyzed.The chemical constituents of stones were analyzed.Results The levels of urine mALB,serumβ2-MG obviously increased on day 1-2 after operation,and reached the peak 2 days after operation.The result after 1-2 days showed significant difference(P 0.05).Compared with the levels before operation,the levels of BUN and Cr slightly increased,with no significant difference(P >0.05).Conclusion The detection of urine mALB,serum β2-MG of patients with urinary stones before and after SWL and analysis of the chemical compositions of urinary stones could provide the evidence for the treatment of patients with urinary stones by SWL in Southeast of Chongqing.
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Objective To explore the diagnostic value of serum Cys-C, hs-CRP, and urine mALB for early renal injury in gonty patients. Methods A total of 100 gonty patients and 50 healthy volunteers were divided into 3 groups, acute phase group (n = 50), intermittent group (n= 50), and healthy control group (n = 50) . The serum Cys C,hs-CRP,and urine creatinine were determined by automatic chemistry analyzer and urine mALB by immunofluorometer equipment, and the results were analyzed in each group. Results The results of mALB/Cr(mg/[g • Cr]), hs-CRP(mg/L), and Cys-C(mg/L)in acute phase group were 11.45±3.55, 5.15±1.98, and 2.62±0.83, in intermittent group were 8.96±1.78, 3.28±1.23, and 0.93±0.26, and in healthy volunteer group were 3.89± 0.76, 1.91±0.57, and 0.78±0.22, respectively. The values of the above three parameters in the acute phase and intermittent groups were significantly higher than those in the healthy control group (P< 0.05) ; and the values in the acute phase group were significantly higher than those in the intermittent group (P<0.05). The abnormal rate of hs-CRP+ Cys-C+ mALB/Cr was 87% in gonty patients. Conclusion Simultaneous determination of mALB/ Cr, hs-CRP, and Cys-C can help to assess the early renal injury in gonty patients.