Study on the evolution of TCM syndromes of 171 cases of Kawasaki disease under the intervention of gamma globulin therapy based on factor analysis / 国际中医中药杂志

Objective:To study the evolution of Traditional Chinese Medicine (TCM) syndromes of 171 cases of Kawasaki disease (KD) under the intervention of gamma globulin therapy based on factor analysis.Methods:A cross-sectional study. 171 cases of KD children hospitalized in the Department of Cardiology of Guangzhou Women's and Children's Medical Center from July 2019 to December 2020 were collected. All patients were treated with intravenous gamma globulin (2 g/kg) for 1 week. According to the results of the treatment with C-ball, 171 children with C-ball sensitive KD were selected to collect the four diagnostic data, and the representative syndromes of defensive level, qi level, yin level, and nutritive level were observed. Factor analysis was used to analyze the evolution of syndrome in 171 children with KD c-ball sensitivity.Results:The result of factor analysis showed that the KMO statistics of 171 children with c-ball sensitivity before treatment was 0.792, and Bartley test was significant ( P<0.01). 16 common factors were extracted, and 23 syndromes were screened, mainly including defensive level disorder, qi level disorder,nutritive level disorder,yin level disorder, heat stagnation and blood stasis syndrome. One week after treatment, the statistic of KMO test was 0.787, and Bartley test was significant ( P<0.01). 9 common factors were extracted, and 10 syndromes were screened, mainly including qi deficiency syndrome, yin deficiency syndrome and blood stasis syndrome. Conclusion:Before treatment, the TCM syndromes in KD C-cell sensitive children are mainly nutritive level disorder, defensive level disorder, qi level disorder yin level disorder, and heat stagnation and blood stasis syndrome; after treatment, the main TCM syndromes are mainly qi deficiency syndrome, yin deficiency syndrome and blood stasis syndrome.

Research status of dialectical prevention and treatment of acute lung injury based on the theory of "Wei qi and Ying Xue" / 中国临床药理学与治疗学

Acute lung injury (ALI) is a common clinical critical respiratory disease. At present, the mechanism of the disease has not been fully elucidated, there is a lack of specific drugs in clinical practice and the mortality rate is high, which is a difficult problem in the medical field. In recent years, traditional Chinese medicine has exerted its unique advantages and efficacy in the prevention and treatment of ALI, which has aroused the attention of domestic and foreign scholars. Based on the theory of "Wei Qi Ying Xue", this paper discusses the current research status of prevention and treatment of ALI by traditional Chinese medicine, and analyzes its pathogenesis, clinical manifestations and corresponding analysis with TCM syndrome. According to the angle of "Wei Qi Ying Xue", the progress of syndrome differentiation and treatment is highly consistent with immune response, inflammatory response, oxidative stress and apoptosis, in order to find new ideas and medication for the prevention and treatment of ALI with integrated traditional Chinese and Western medicine.

Distinguishing the "Wei Qi Ying Xue" syndrome differentiation from the "three certificates and three methods" to the diagnosis of sepsis / 中华危重病急救医学

The?"three?certificates?and?three?methods"?is?a?combination?of?Chinese?and?Western?medicine?for?the?treatment?of?sepsis?proposed?by?Professor?Wang?Jinda,?a?pioneer?in?Chinese?emergency?medicine.?The?"Wei?Qi?Ying?Xue"?syndrome?differentiation?is?a?dialectical?theory?proposed?by?Ye?Tianshi,?a?famous?doctor?in?the?Qing?Dynasty,?for?the?treatment?of?warm?diseases.?The?"three?certificates?and?three?methods"?theory?of?"toxin-heat?syndrome"?(inflammation?storm)?to?the?"blood?stasis?syndrome"?(coagulation?storm)?conversion?mainly?focus?on?the?"Wei?Qi?Ying?Xue"?syndrome?differentiation?of?the?"Wei,?Qi?syndrome"?to?"Ying,?Xue?syndrome",?and?poison.?The?conversion?of?"toxin-heat?syndrome"?to?"blood?stasis?syndrome"?is?a?watershed?in?the?progression?of?common?infections?to?sepsis.?The?timely?application?of?Xuebijing?injection?can?cut?off?this?transformation,?which?is?one?of?the?reasons?why?Xuebijing?injection?can?treat?sepsis.

Differentiation of Wei,Qi,Ying and Xue on Acute Contagious Conjunctivitis / 浙江中医药大学学报

[Objective] To explore the differentiation of Wei Qi Ying Xue on febrile disease,its treatment on external oculopathy of acute contagious conjunctivitis,which is failed in western medicine.[Method] Under the characteristics of the disease and the theory of differentiation of Wei Qi Ying Xue,its location is in Wei system,it should dispel with pungent and cool drugs to remove lung hotness,by applying revised normal pungent and cool prescription Yinqiao San;for disease in both Wei and Qi,it should use revised Yinqiao San and Baihu Tang to relieve exterior syndrome and clear hot toxin by pungent and cool drugs;if the location is in Qi system,it should take revised Baihu Tang and Dachengqi Tang to clear away heat and toxic material or by purgation;if it happens both in Qi and Ying(blood),take Qingying Tang and Xijiao Dihuang Tang to clear away heat and toxic material,cool and dispel blood;when the heat is removed and the fluid is injured,the bad heat is pondering,it should take Shashen Maidong Tang to clear away the remaining heat and produce fluid.[Result] It gets good result with correct differentiation.[Conclusion] As long as you have correct differentiation of signs,can the febrile disease theory in national medicine be applied in the treatment of external oculopathy flexibly.