The role of neophobia in a pioneer olfactory enrichment for amazons, macaws, and toucans / El papel de la neofobia en un enriquecimiento olfativo pionero para guacamayos, loros y tucanes

Abstract Introduction: Despite sensory enrichment being critical for ensuring the well-being of captive wild animals, smells are not being included in enrichment protocols for birds. For this group, neophobia can be a problem when it comes to implementing new enrichment devices. Objective: To explore how participation in an olfactory enrichment and latency times varies between bird taxonomic groups (Amazona spp. / Ara spp. / Ramphastos spp.). Methods: We exposed 257 birds to a scent enrichment, and we recorded which individuals engaged with it and the time they took to interact with it. Results: We discovered that participation by toucans in the enrichment was higher compared to amazons and macaws. Furthermore, latency time to interact with the enrichment was higher in amazons that in the other species. Our findings could suggest that toucans are neophilic species which could benefit from higher exploration rates. Amazons on the contrary seem to be particularly neophobic, possibly because of their less opportunistic feeding habits compared to toucans and their higher vulnerability to predation compared to macaws. Conclusion: These results point out that toucans would be more inclined to engage in environmental enrichments, while a more natural design using smells inside familiar objects could be a more successful enrichment for psittacids.

Resumen Introducción: A pesar de que el enriquecimiento sensorial es fundamental para garantizar el bienestar de los animales silvestres en cautiverio, los olores no son incluidos de forma rutinaria en los protocolos de enriquecimiento para aves. Además, en el caso de estos animales, la neofobia puede ser un problema a la hora de implementar nuevos dispositivos de enriquecimiento. Objetivo: Explorar cómo varía la participación y la latencia en la interacción con un enriquecimiento olfativo entre grupos taxonómicos de aves (Amazona spp. / Ara spp. / Ramphastos spp.). Métodos: Expusimos a 257 aves a un enriquecimiento olfativo y registramos qué individuos participaron y el tiempo que tardaron en interactuar con él. Resultados: La participación en el enriquecimiento fue mayor en los tucanes en comparación con las amazonas y los guacamayos. Además, el tiempo de latencia para interactuar con el enriquecimiento fue mayor en las amazonas que en las otras especies. Nuestros hallazgos sugieren que los tucanes son especies neofílicas que podrían beneficiarse de tasas de exploración más altas. Por otro lado, las amazonas parecen ser particularmente neofóbicas, posiblemente debido a sus hábitos alimenticios menos oportunistas en comparación con los tucanes y a su mayor vulnerabilidad a la depredación en comparación con los guacamayos. Conclusión: Estos resultados señalan que los tucanes serían más proclives a participar en enriquecimientos ambientales, mientras que un diseño que utilice olores dentro de objetos más naturales o familiares podría ser más exitoso para las psitácidas.

Ethics and Welfare in invertebrates: a stepping-stone to research and animal production / Ética y bienestar en invertebrados: una piedra fundamental en investigación y producción animal

Abstract Introduction: Even though only a few species are considered to be dangerous, pests or vectors, the majority of invertebrates produce a feeling of aversion in humans. This has contributed to the delay in the development of ethical considerations as regards this group in contrast with vertebrates, with the exception of cephalopods. Objective: In the present study, we provide an overview of the current situation on animal ethics and welfare in order to contribute to the development of a framework for ensuring invertebrate welfare. Methods: Today, animal welfare is multidisciplinary in nature to a very high degree as it includes ethology, physiology, pathology, biochemistry, genetics, immunology, nutrition, cognitive-neural, veterinary medicine, and ethics. Animal welfare is a complex concept, difficult to achieve successfully from one perspective. Results: As a consequence, we propose to include the five domains (nutrition, environment, health, behaviour and mental state) along with the three conceptions (basic health and functioning, affective state and natural living), as well as the 5R Principle (Replace, Reduction, Refinement, Respect and Responsibility) in seeking to achieve a comprehensive welfare state. Conclusions: We consider that in both research and animal production, the individual and collective ethical concerns coexist and, in fact, the main moral concern to account for is the collective one and that, within that collective view, the individual moral concern should be applied with responsibility and respect for the individual. Finally, we propose a practical example of invertebrate welfare production in sea urchin aquaculture with the aim of including animal production of invertebrates in this important discussion.

Resumen Introducción: Aunque sólo unas pocas especies son consideradas peligrosas, plagas o vectores, la mayoría de los invertebrados producen un sentimiento de aversión en el ser humano. Esto ha contribuido al retraso en el desarrollo de consideraciones éticas respecto a este grupo en comparación con los vertebrados, a excepción de los cefalópodos. Objetivo: En el presente trabajo, proporcionamos una visión general de la situación actual en materia de ética y bienestar animal con el fin de contribuir al desarrollo de un marco para garantizar el bienestar de los invertebrados. Métodos: Hoy en día, el bienestar animal es de naturaleza multidisciplinaria en un grado muy alto, ya que incluye etología, fisiología, patología, bioquímica, genética, inmunología, nutrición, cognitivo-neural, medicina veterinaria y ética. El bienestar animal es un concepto complejo, difícil de lograr con éxito desde una sola perspectiva. Resultados: Como consecuencia, proponemos incluir los cinco dominios (nutrición, ambiente, salud, comportamiento y estado mental) junto con las tres concepciones (Salud básica y funcionamiento, estado afectivo y vida natural), así como el Principio 5R (Reemplazar, Reducir, Refinar, Respetar y Responsabilidad) en la búsqueda de alcanzar un estado de bienestar integral. Conclusiones: Consideramos que tanto en la investigación como en la producción animal coexisten las preocupaciones éticas individuales y colectivas y, de hecho, la principal preocupación moral a dar cuenta es la colectiva y que, dentro de esa visión colectiva, se debe aplicar la preocupación moral individual. con responsabilidad y respeto por la persona. Finalmente, proponemos un ejemplo práctico de producción de bienestar de invertebrados en la acuicultura de erizos de mar con el objetivo de incluir la producción animal de invertebrados en esta importante discusión.

Vivência e expectativas de doulas em região brasileira de fronteira / Experience and expectations of doulas in a Brazilian border region

RESUMO O estudo buscou compreender a vivência e as expectativas das doulas que atuam ou atuaram em dois municípios de região de fronteira: Foz do Iguaçu e Cascavel, Paraná, Brasil. Tratou-se de uma pesquisa qualitativa pautada no referencial da Fenomenologia Social. A coleta das informações deu-se por entrevistas com roteiro semiestruturado em língua portuguesa. As entrevistas foram feitas on-line. Os resultados foram classificados em seis categorias: motivação para tornar-se doula, conhecimento sobre o papel da doula, o cotidiano das doulas, abarcando as subcategorias de experiências exitosas e desafios da atividade na região de fronteira, a invisibilidade da doulagem, as expectativas enquanto doulas frente ao cenário obstétrico e o esperado da sua atuação profissional. O estudo permitiu compreender a vivência das doulas e o conhecimento do papel da sua função no Sistema Único de Saúde (SUS), no setor privado e em partos domiciliares, evidenciando a importância da atuação multiprofissional. Foram ponderadas resistências no cenário obstétrico por desconhecimento dos profissionais da assistência sobre o papel da doula. Em relação à atuação na região de fronteira, as doulas relataram o acompanhamento de mulheres paraguaias no Brasil e, com menos frequência, no Paraguai. As barreiras culturais e linguísticas foram destacadas como obstáculos para o exercício profissional em outro país.

ABSTRACT The study sought to understand the experience and expectations of doulas who worked or worked in two municipalities in the border region: Foz do Iguaçu and Cascavel, Paraná, Brazil. This was a qualitative research based on the framework of Social Phenomenology. The collection of information took place through interviews with a semi-structured script in Portuguese. The interviews were done online. The results were classified into six categories: motivated to become a doula, knowledge about the role of the doula, the daily life of the doulas, covering the subcategories of successful experiences and challenges of the activity in the border region, the invisibility of the doula, the expectations as doulas facing the obstetric scenario and what is expected of their professional performance. The study made it possible to understand the experience of doulas and knowledge of the role of their role in the Unified Health System (SUS), in the private sector and in home births, highlighting the importance of multidisciplinary action. Resistance in the obstetric scenario was considered due to the lack of knowledge on the part of care professionals about the role of the doula. Regarding work in the border region, the doulas reported accompanying Paraguayan women in Brazil and, less frequently, in Paraguay. Cultural and linguistic barriers were highlighted as reasons that make professional practice in another country unfeasible.

Analysis on the Current Status and Ethics Review Key Points of Electronic Informed Consent / 中国医学伦理学

Informed consent is one of the key elements to protect the rights and welfare of the patients or research subjects. With the development of electronic information technology, the diversity and convenience brought by the electronization makes the electronic informed consent (E-Consent) come into being. European and American countries have begun to apply E-Consent in the field of clinical trials, established a relatively perfect E-Consent platform and software system, and initially formed the guiding principles and recommendations of E-Consent. However, the implementation of E-Consent is still less in China, and there is no targeted legal basis and guidelines for ethical review. Therefore, this paper explored the implementation potential of E-Consent domestically by analyzing the application scenarios, advantages and disadvantages, and feasibility of E-Consent, and tried to establish the practical ethic review points of E-Consent based on the basic principles of ethical principles, to ensure that clinical trials have an appropriate E-Consent process.

Survival analysis of Chagas disease patients, beneficiaries of social security and social assistance in Brazil, 1942-2016 / Análise de sobrevida de portadores da doença de Chagas, beneficiários da previdência e da assistência social no Brasil, 1942-2016

ABSTRACT Objective To analyze the survival of patients with Chagas disease, beneficiaries of social security and social assistance, in Brazil, from 1942 to 2016. Methods This is a retrospective cohort study with data from the Brazilian Ministry of Social Security. The event of interest was death, and the survival functions were estimated by the Kaplan-Meier and Cox regression methods. Results In the period "onset of the disease until death", women (HR=0.54; 95%CI 0.43-0.53) and receiving social security benefits (HR=0.13; 95%CI 0.11-0.23) were associated with longer survival. Lower survival was associated with the cardiac form of the disease (HR=2.64; 95%CI 2.23-3.12), living in a rural area (HR=1.23; 95%CI 1.14-1.21), and manifestation of the disease between the years 2000 and 2016 (HR=5.32; 95%CI 4.74-5.93). Likewise, in the period "work disability until death", women (HR=0.51; 95%CI 0.41-0.52) and receiving social security benefits (HR=0.24; 95%CI 0,14-0.45) were associated with longer survival, as well as the cardiac form of the disease (HR=1.95; 95%CI 1.83-2.13), living in a rural area (HR=1.31; 95%CI 1.21-1.54), and manifestation of the disease between 2000 and 2016 (HR=1.53; 95%CI 1.33-1.71) were associated with lower survival. Conclusion The main predictors of mortality and survival of patients with Chagas disease who receive social security and assistance benefits in Brazil were presented. These findings can guide the definition of priorities for follow-up actions by Primary Health Care, currently recommended for the longitudinal management of the disease.

RESUMO Objetivo Analisar a sobrevida de portadores da doença de Chagas, beneficiários da previdência e da assistência social no Brasil, 1942-2016. Métodos Estudo de coorte retrospectivo com dados do Ministério da Previdência Social. O evento de interesse foi o óbito, e as funções de sobrevida foram estimadas pelos métodos Kaplan-Meier e de regressão de Cox. Resultados No período "início da doença até o óbito", o sexo feminino (HR=0,54; IC95% 0,43-0,53) e recebimento de benefícios previdenciários (HR=0,13; IC95% 0,11-0,23) foram associados a maior sobrevida. A menor sobrevida esteve associada à forma cardíaca da doença (HR=2,64; IC95% 2,23-3,12), residência em zona rural (HR=1,23; IC95% 1,14-1,21) e manifestação da doença entre os anos de 2000 e 2016 (HR=5,32; IC95% 4,74-5,93). Da mesma forma, no período "incapacidade laboral até o óbito", o sexo feminino (HR=0,51; IC95% 0,41-0,52) e o recebimento de benefícios previdenciários (HR=0,24; IC95% 0,14-0,45) foram associados a maior sobrevida, assim como forma cardíaca da doença (HR=1,95; IC95% 1,83-2,13), residência em zona rural (HR=1,31; IC95% 1,21-1,54) e manifestação da doença entre os anos de 2000 e 2016 (HR=1,53; IC95% 1,33-1,71) associaram-se a menor sobrevida. Conclusão Os principais preditores de mortalidade e sobrevida de portadores de doença de Chagas que recebem benefícios previdenciários e assistenciais no Brasil foram apresentados. Estes achados podem nortear a definição de prioridades de ações de acompanhamento pela atenção primária à saúde, preconizada atualmente para o manejo longitudinal da doença.

Efectos de la pandemia por COVID-19 en determinantes sociales de familias del área metropolitana de Bucaramanga

Introducción: La pandemia por COVID-19 trajo consigo grandes cambios a nivel socioeconómico, producto de las medidas tomadas para mitigar su expansión, que implicó cierre de colegios y dificultad para el acceso a servicios de salud. Sin embargo, no se cuenta con mucha información respecto al impacto que estas medidas han tenido en la salud y el bienestar de niños y adolescentes, por lo cual se desarrolló una encuesta virtual para conocer la dimensión de los efectos de la pandemia en el bienestar integral de los menores y sus familias. Metodología: Estudio observacional de corte transversal que se realizó mediante la aplicación de una encuesta en formato electrónico a padres de familia de niños y adolescentes del Área Metropolitana de Bucaramanga. Resultados: Se obtuvieron 960 respuestas. El 25,63 % de los encuestados refieren cancelación de citas médicas. El 98 % de los estudiantes pudo continuar las actividades académicas durante el aislamiento. El factor económico fue la principal causa de preocupación en el periodo de la encuesta. Discusión: Durante el periodo de aislamiento, los problemas de salud mental, las dificultades para el acceso a herramientas para la educación virtual y las barreras para la atención, propias de la emergencia sanitaria, causaron efectos significativos en la calidad de vida de los menores. Conclusiones: Ante emergencias sanitarias, se deben mantener los servicios de atención en salud de la misma forma que se hacía previo a la ocurrencia del evento, como los programas de vacunación, crecimiento y desarrollo, promoción y prevención, además de la continuidad de la escolaridad.

Introduction: The COVID-19 pandemic has brought great changes along with, some of those were at the socioeconomic level, as a result of the actions taken to mitigate the virus expansion, which involved the closure of schools and restriction in accessing to some health services. However, there is not much information regarding the impact that these measures have had on the health and well-being of children and adolescents, for this reason, a virtual survey was developed to find out the dimension of the pandemic's effect on the comprehensive welfare of minors and families. Methodology: Cross-sectional observational study, which was carried out by applying a survey in electronic format to parents of children and adolescents in the Metropolitan Area of Bucaramanga. Results: A total of 960 responses were obtained. Of those surveyed, 25,63% refer cancellation of medical appointments. The 98% of students were able to continue academic activities during isolation. The economic factor was the main cause of concern in the survey period. Discussion: During the isolation period, mental health problems, difficulties in accessing tools for virtual education and barriers to care, typical of the health emergency, caused a significant effects on the quality of life of youngsters. Conclusions: In the event of health emergencies, health care services should be maintained in the same way as before the occurrence of the event, such as vaccination, growth and development, promotion and prevention programs, in addition to the continuity of schooling.

Evolución del riesgo y protección en la infancia y la adolescencia / Evolution of risk and vulnerability in childhood and adolescence

(analítico) Los factores de riesgo y protección pueden ser utilizados para evaluar, prevenir e intervenir en el maltrato infantil. El objetivo de este estudio es analizar longitudinalmente el riesgo en la infancia y la adolescencia, para determinar qué factores pueden ser empleados como indicadores de evolución. Se empleó una muestra de 102 niños, niñas y adolescentes que participaban en el sistema de bienestar infantil español, en tres momentos temporales. Los resultados indicaron que existe una evolución del riesgo, con una tendencia general de disminución de riesgos e incremento de elementos protectores. Nuestros hallazgos identificaron la existencia de factores dinámicos y estáticos. Este estudio pone de manifiesto la relevancia de la atención e intervención continuada y a largo plazo para fortalecer los factores de protección y disminuir los de riesgo en niños, niñas y adolescentes.

(analytical) Risk and protective factors can be used for risk and needs assessments, prevention, and intervention in cases involving mistreatment of children. The aim of this study is to provide a longitudinal analysis of risks and vulnerabilities in childhood and adolescence, with the goal of determining which factors can be used as indicators for progress with cases. A sample of 102 children and adolescents supported by the child welfare system in Spain was used along with measurements based on three different points in time. The study's results indicated that there is a change in risk levels, with a general trend of decreasing risk and increasing protective elements. The study's findings identified the existence of a group of dynamic factors and another group of static factors. This study highlighted the relevance of continuous and long-term care and intervention in order to strengthen protection and decrease risks for children.

(analítico) Os factores de risco e protecção podem ser utilizados para avaliar, prevenir e intervir em casos de maustratos a crianças. O objectivo deste estudo é analisar o risco na infância e adolescência longitudinalmente, a fim de determinar que factores podem ser utilizados como indicadores de evolução. Uma amostra de 102 crianças e adolescentes participantes no sistema espanhol de bem-estar infantil foi utilizada em três pontos no tempo. Os resultados indicaram que existe uma evolução do risco, com uma tendência geral de diminuição do risco e aumento dos elementos protectores. Os nossos resultados identificaram a existência de factores dinâmicos e estáticos. Este estudo destaca a relevância dos cuidados e intervenções contínuos e a longo prazo para reforçar os factores de protecção e diminuir os factores de risco nas crianças.

Salud y bienestar en las representaciones sociales de los profesionales de salud Latinoamérica 2019 - 2020 / Health and well-being in the social representations of health professionals in selected Latin American countries 2019-2020

Resumen Objetivos: La investigación se propuso tres objetivos: describir la representación social de salud y bienestar; caracterizar la labor de los profesionales de salud para promover el bienestar; establecer similitudes y diferencias entre lo que conocen y realizan, respecto del concepto de la Organización Mundial de la Salud. Materiales y métodos: Es un estudio descriptivo, transversal, multicéntrico (Cuba, México, Panamá y Perú); después de una revisión bibliográfica, se llevó cabo una encuesta y consulta a expertos. Se utilizó un muestreo no probabilístico y se realizaron análisis de estadística descriptiva. Resultados: Los profesionales de salud, perciben el bienestar muy agradable y cómodo, posible, dulce, bueno, responsable, flexible, seguro, blanco, algo ligero, pero un poco corto y difícil; a la salud la perciben muy agradable, posible, cómoda, flexible, dulce, responsable, segura, buena, blanca, ligera y larga pero difícil; la mayoría cree conocer los conceptos salud y bienestar de OMS/OPS, pero al compararlos con los establecidos por estos organismos, no son correctos, ni completos y su conocimiento resulta insuficiente. Conclusiones: Los profesionales de salud no tienen una comprensión total de la relación entre ambos conceptos; la mayoría realiza las acciones para promover el bienestar que le resultan fáciles; no se perciben como entes activos y transformadores en las actividades generadoras de una vida saludable y, por tanto, no se encuentran en consonancia con las transformaciones necesarias que privilegian salud y bienestar.

Abstract Objectives: The research proposed three objectives: to describe the social representation of health and well-being; characterize the work of health professionals to promote well-being; establish similarities and differences between what they know and do, with respect to the concept of the World Health Organization. Materials and methods: It is a descriptive, cross-sectional, multicenter study (Cuba, Mexico, Panama and Peru); after a literature review, a survey and expert consultation were carried out. Non-probabilistic sampling was used and descriptive statistical analyzes were performed. Results: The health professionals, perceive well-being as very pleasant and comfortable, possible, sweet, good, responsible, flexible, safe, white, somewhat light, but a bit short and difficult; health is perceived as very pleasant, possible, comfortable, flexible, sweet, responsible, safe, good, white, light and long but difficult; most believe they know the concepts of health and well-being of WHO/PAHO, but when compared to those established by these organizations, they are not correct or complete, and their knowledge is insufficient. Conclusions: In conclusion, they do not have a full understanding of the relationship between both concepts; most take actions to promote well-being that are easy for them; they are not perceived as active and transforming entities in the activities that generate a healthy life and therefore, they are not in line with the necessary transformations that privilege health and well-being.

Factores laborales, actitudes de género y bienestar asociados al conflicto trabajo y familia en Chile / Labor Factors, Gender Attitudes, and Welfare Associated With Work-Family Conflict in Chile / Conflict in Chile Fatores laborais, atitudes de gênero e bem-estar associados ao conflito laboral e familiar no Chile

La incidencia de factores sociales, culturales y normativos en el conflicto trabajo-familia ha sido abordada a nivel internacional, pero sin evidencia en Chile. En este estudio se analizó la incidencia de distintos factores sociolaborales, de género y las actitudes hacia el Esta- do de bienestar en el conflicto trabajo-familia, en una muestra de 550 trabajadores con hijos menores de 14 años, residentes de Santiago de Chile. Se aplicó un análisis de regresión logística para determinar las variables predictoras del conflicto trabajo-familia, y se profundizó en una de las direcciones, el conflicto de la familia a trabajo. Los resultados mostraron que las dificultades para conciliar en la empresa influyen positivamente en el conflicto trabajo-familia. Además, el ingreso mínimo influye en el conflicto trabajo-familia; mientras que el tiempo de cuidado incide en el conflicto familia a trabajo.

The incidence of social, cultural, and normative factors on work/family conflict has been addressed internationally. However, there is no evidence for the case of Chile. This study analyzed the effect of attitudes towards the welfare state and different socio-labor factors on this conflict in 550 working parents with children under 14 in Santiago, Chile. The logistic regression analysis showed that difficulties in reconciling work and family life in the company positively influence the conflict. In addition, earning the minimum wage generates greater conflict, while care time has an impact on family-to-work conflict.

A incidência de fatores sociais, culturais e normativos no conflito trabalho/família foi abordada internacionalmente, mas sem evidências no Chile. Neste estudo, analisou-se a incidência de diferentes fatores sociolaborais, gênero e atitudes perante o estado de bemestar no conflito trabalho/família em uma amostra de 550 trabalhadores com filhos menores de 14 anos residentes em Santiago, Chile. Aplicou-se uma análise de regressão logística para determinar as variáveis preditoras do conflito trabalho/ família, e aprofundou-se em uma das direções, o conflito da família em relação ao trabalho. Os resultados mos- traram que as dificuldades de conciliação na empresa influenciam positivamente no conflito trabalho/família. Além disso, a renda mínima influencia o conflito trabalho/ família; enquanto o tempo de cuidado afeta o conflito família em relação ao trabalho.

Gobernando la crianza en familias pobres: ONG y gestión durante la pandemia

(analítico) El artículo analiza prácticas de crianza de familias pobres ubicadas en la ciudad de Ibagué (Colombia), que emergen en su relación con las ONG que las intervienen en el contexto de la pandemia por covid-19. La metodología empleada fue la etnografía, en diálogo con estrategias dialógicas y participativas. Se evidenciaron dos tipos de prácticas de crianza: alimentaria y de acompañamiento educativo. Mientras la primera se gestiona por medio de donaciones, sujetas a las lógicas del mercado, la segunda se basa en la asignación de roles educativos a los acudientes para que estos instruyan a sus hijos e hijas con base en los parámetros del Estado. Como conclusión, se evidencia que estas intervenciones buscan que las familias autogestionen su precariedad, en el marco de la legitimación de un orden social neoliberal.

(analytical) This article analyzes the parenting practices of poor families located in the city of Ibagué (Colombia), which emerged in the families' relationships with an NGO that provided them with support during the COVID-19 pandemic. An ethnographic methodology was used, complemented with dialogic and participatory strategies. Two types of parenting practices were identified: food-based care and educational support. While the first was based upon receiving donations and was subject to market dynamics, the second was based on the allocation of educational roles to parents and caregivers so that they could teach their children based on the State's guidelines. The authors conclude that these interventions support families to selfmanage their precarious situation in the framework of the legitimation of a neoliberal social order.

(analítico) O artigo analisa práticas na formação de famílias pobres, localizadas na cidade de Ibagué (Colômbia), que emergem na sua relação com as ONGs, que as intervêm, no contexto da pandemia por Covid-19. A metodologia aplicada foi a etnografia, em diálogo com estratégias dialógicas e participativas. Evidenciaram-se dois tipos de práticas de formação: alimentar e de acompanhamento educativo. Enquanto a primeira se gestiona através de doações, sujeitas às lógicas do mercado, a segunda se baseia na designação de papéis educativos aos pais ou responsáveis para que estes instruam aos seus filhos e filhas com base nos parâmetros do Estado. Como conclusão, se evidencia que estas intervenções procuram que estas famílias autogestionem a sua precariedade, no marco da legitimação de uma ordem social neoliberal.

Interrupção legal da gravidez em crianças: o melhor interesse da gestante nas veredas do direito, da medicina e da ética / Legal termination of pregnancy in children in Brazil: the principle of the best interests of the child in the paths of law, medicine, and ethics / Interrupción legal del embarazo en niñas em Brasil: el principio del interés superior del niño en los caminos del derecho, la medicina y la ética

Objetivo: analisar o direito à interrupção legal da gravidez sob o marco teórico do princípio do melhor interesse da criança. Dentre os objetivos específicos, busca-se analisar a postura do Judiciário e do Ministério Público nos casos apresentados, os fundamentos jurídicos para o exercício do direito ao aborto em casos de estupro de vulnerável, os contornos teóricos do princípio do melhor interesse da criança, além de aspectos médicos, tais como a (in)existência de marco temporal para a interrupção da gravidez nos casos permitidos pela legislação, bem como a (im)possibilidade do exercício da objeção de consciência por médicos nesse contexto. Metodologia: adota-se a vertente jurídico-sociológica e a investigação jurídico-propositiva, por meio de raciocínio indutivo. Utiliza-se análise documental e bibliográfica, por meio de revisão bibliográfica qualitativa. Parte-se do marco teórico do princípio do melhor interesse da criança e do adolescente, previsto na Lei nº 8.069/1990, para testar a hipótese de que a interrupção legal da gravidez deve ser compreendida prima facie como o curso de ação que melhor se adequa ao princípio do melhor interesse da criança. Resultados: a gravidez em criança, por si só, já configura a violação de um direito fundamental. A interrupção da gestação nos casos de estupro de vulnerável é direito fundamental, garantido expressamente por lei, sem qualquer condicionante temporal ou qualitativa. Conclusão: confirmou-se a hipótese de que a interrupção legal da gravidez deve ser compreendida prima facie como o curso de ação que melhor se enquadra ao princípio do melhor interesse da criança.

Objective: to analyze the right to legal abortion within the theoretical framework of the principle of the best interests of the child. The specific objectives are to analyze the position of the Judiciary and the Prosecution in two cases, the legal basis of the right to abortion in cases of statutory rape, the theoretical framework of the principle of the best interests of the child, and medical aspects such as the (non-)existence of a time frame for abortion in legally admissible cases and the (im)possibility of the exercise of conscientious objection by physicians in this context. Methods: this paper makes use of the sociological of law and the legal-propositional research directions and follows an inductive thinking approach. Documentary and bibliographic analysis is conducted through a qualitative bibliographical review. This paper starts from the theoretical framework of the principle of the best interests of the child provided by Law No. 8.069/1990 to test the hypothesis that legal abortion is prima facie the procedure that best complies with the principle of the best interests of the child. Results: the pregnancy of a child is in itself a violation of a fundamental right. Abortion in the case of rape of a vulnerable person is a fundamental right explicitly guaranteed by law, without temporal or qualitative constraint.Conclusion: the hypothesis was confirmed, so that legal abortion should be understoodprima facieas the course of action that best corresponds to the principle of the best interests of the child.

Objetivo: analizar el derecho a la interrupción legal del embarazo bajo el marco teórico del principio del interés superior del niño. Entre los objetivos específicos buscamos analizar la posición del Poder |Judicial y del Ministerio Público en los casos presentados, los fundamentos jurídicos para el ejercicio del derecho al aborto en casos de violación de persona vulnerable, los contornos teóricos del principio del interés superior del niño, además de aspectos médicos, como la (in)existencia de un plazo para la interrupción del embarazo en los casos permitidos por la ley, así como la (im)posibilidad de objeción de conciencia por parte de los médicos en este contexto. Metodología: se adopta el aspecto jurídico-sociológico y la investigación jurídico-proposicional, a través del razonamiento inductivo. Se utiliza el análisis documental y bibliográfico, a través de una revisión bibliográfica cualitativa. Parte del marco teórico del principio del interés superior del niño y del adolescente, previsto en la Ley n. 8.069/1990, para contrastar la hipótesis de que la interrupción legal del embarazo debe entenderse prima facie como el curso de acción que mejor se adapta al principio del interés superior del niño. Resultados: el embarazo infantil, por sí solo, ya es una vulneraciónde un derecho fundamental. La interrupción del embarazo en casos de violación de una persona vulnerable es un derecho fundamental, expresamente garantizado por la ley, sin ninguna condición temporal o cualitativa. Conclusión: a partir de los casos presentados, siguiendo la metodología señalada anteriormente, se confirmó la hipótesis de que la interrupción legal del embarazo debe entenderse prima facie como el curso de acción que mejor se ajusta al principio del interés superior del niño.

Concessão dos benefícios assistenciais para pessoas com paralisia cerebral no Brasil: tendência temporal e análise espacial / Continuous cash benefit for people with cerebral palsy in Brazil: temporal trend and spatial analysis

Objetivo: Analisar a tendência temporal e distribuição espacial dos benefícios concedidos para as pessoas com Paralisia Cerebral. Método: Estudo ecológico em que foram incluídos os benefícios concedidos às pessoas com Paralisia Cerebral, nos períodos de 2004 a 2016, no Brasil. Os dados foram coletados do Instituto Nacional de Seguridade Social e Instituto Brasileiro de Geografia Estatística. Utilizou-se o software Join Point Regression, 4.5.0.1, sendo as tendências classificadas em decrescente; crescente e estacionária. Na distribuição espacial foi realizada Análise Exploratória de Dados Espaciais com o software QGIS versão 3.18. Resultados: Observou-se uma tendência decrescente do BPC do ano de 2004 até o ano de 2016, no Brasil. Na região Norte o número de concessões aumentou de 2004-2010, mas, após isso, houve um decréscimo. Já as regiões Sudeste, Sul e Centro Oeste apresentaram tendência decrescente em todo o período analisado. Na análise espacial, as regiões Norte e Nordeste apresentaram maior frequência de BPC proporcionalmente à população com pessoas até 19 anos, aos domicílios e às famílias com até um salário mínimo nas unidades federativas do Brasil. Conclusão: Foi possível observar a diminuição de concessões do BPC em todas as regiões do país no período de 2004 a 2016. As regiões que possuem os índices mais elevados de distribuição do BPC são Nordeste e Norte, reconhecidamente, as que possuem os maiores indicadores de pobreza e extrema pobreza do país

Objective: To analyze the temporal trend and spatial distribution of benefits granted to people with Cerebral Palsy. Method: An ecological study that included the benefits granted to people with Cerebral Palsy, from 2004 to 2016, in Brazil. Data were recorded from the National Institute of Social Security and the Brazilian Institute of Geography. The software Join Point Regression, 4.5.0.1 was used and the trends were classified as increasing; growing and stationary. In the spatial distribution, Exploratory Spatial Data Analysis was performed with the QGIS software version 3.18. Results: There is a downward trend in BPC from 2004 to 2016 in Brazil. In the North region, the number of concessions increased from 2004-2010, but after that, there was a decline. The regions and Center West, on the other hand, show a decreasing trend throughout the Southeast and South period. In the spatial analysis, the most frequent North and Northeast regions of BPC in proportion to the population with people aged 19 years, to families with units up to one minimum wage in the federative units of Brazil. Conclusion: A decrease in BPC extensions was observed in all regions of the country in the period 2016. Poverty and extreme poverty in the country

Evaluation of Microbiological Quality of Halal Beef Intended for Export from Khartoum State, Sudan

Aims: To evaluate halal criteria of beef microbiological quality intended for export in two slaughterhouses. Study Design: A cross-sectional study. Place and Duration of Study: Khartoum State, Sudan between August and November 2022. Methodology: Samples were collected by using the non-destructive dry swab method for microbiological quality sampling of beef and a standardized checklist to evaluate good manufacturing practices (GMPs) and good hygienic practices (GHPs). Restraining methods were categorized as “modern method” where the full inversion rotary casting box was used which resembled slaughterhouse “A” or “conventional method” where a large-sized hammer for blowing the skull was used and this resembled slaughterhouse “B”. A total of 80 male beef cattle were investigated after arrival in the lairages of the designated slaughterhouses. Forty carcasses from each slaughtering method were randomly chosen and swabbed. Results: The results revealed that halal criteria for the slaughtering methods in slaughterhouse (A) was 100%, while slaughterhouse (B) was 83.2%. Also, this study revealed poor personal hygiene as slaughterhouse A scored 53.2%, while slaughterhouse B scored 33.2% for personal hygiene evaluation. The mean total bacterial count (TBC) was found to be 4.556 x 10? cfu/ml and 5.53275 X 10? cfu/ml in slaughterhouses A and B, respectively with highly significant differences compared to the standard permissible limits (1x 10?cfu/ml) with p ?0.05, while there were no statistically significant differences (0.847) within slaughterhouses with p ?0.05. Furthermore, the mean total coliform count (TCC) was found to be 16.4795 X10²cfu/ml and 47.8670 X 10²cfu/ml in slaughterhouses A and B, respectively with a highly significant difference compared to the standard permissible limits (1x10²cfu/ml) with p ?0.05 and also with highly significant differences (0.000) between slaughterhouses themselves with p ?0.05. Conclusion: The study concluded that both slaughterhouses failed to meet the requirements of the various beef halal criteria.

Behavioral assessment of Tambaqui juveniles (Colossoma macropomum) exposed to different ambient colors and social stress

Animal welfare regards the quality of life and the environment in which animals live or are exposed. Hence the importance of studies assessing the environmental influence on the biology and behavior of fishes from the Colossoma macropomum species, considering their higher potential for fish-farming and as a test organism in scientific research. This study aimed to assess, in a controlled environment, the behavioral changes expressed by juveniles from the Colossoma macropomum species exposed to different ambient colors or social situations. The results did not show an influence from the different ambient colors or social situations on fish distribution in the water column. The color pattern showed dark tones in black- and blue-colored environments, and light tones in white-colored environments or with the presence of a mirror. The time of locomotor activity/frequency did not change in any of the treatments of exposure to environments with colors and a mirror. Moreover, the fishes remained with folded fins and a straight posture, maintaining a pattern of rhythmic operculum beating in a normal frequency range described for the species. This suggests that animal welfare did not change in any of the situations tested and that there was a pattern of adaptive response to the type of environment.

Avaliação das políticas sociais brasileiras para a eliminação da desigualdade de gêneros / Assessment of the contribution of Brazilian social policies to the elimination of gender inequality

O Estado de Bem-estar é o resultado de uma evolução histórica, econômica, política e social, e dependendo do regime em cada país, haverá políticas sociais mais abrangentes que outras. Tais políticas apresentam um conjunto de garantias necessárias para a redução das distorções provenientes do modelo industrial capitalista que emergiu na Europa, no final do século XIX. Dentre os exemplos mais exitosos destacamos o regime dinamarquês, que ganha destaque neste trabalho por refletir o sistema de licenças familiares mais completo e eficiente, capaz de garantir acesso universal às mães e seus filhos pequenos, minimizando a estratificação social e a mercadorização das garantias sociais. O Brasil está longe dessa realidade, porém passou a desenvolver, após 1930, uma série de políticas sociais as quais, a partir da Constituição Federal de 1988, passaram a ter caráter universal. A presente pesquisa teve como objeto a análise comparativa das políticas sociais dirigidas às famílias com crianças pequenas no Brasil e na Dinamarca, e como objetivo analisar a contribuição das políticas sociais brasileiras para a superação da desigualdade de gêneros, para a promoção da cidadania das mulheres e do desenvolvimento das crianças. A análise centrou-se na regulamentação das licenças de proteção da maternidade, paternidade e parentalidade; nos subsídios atribuídos às famílias com crianças pequenas e na política de creches dos dois países. A metodologia utilizada foi baseada, principalmente, numa revisão bibliográfica e da legislação, utilizando como fonte secundária a base de dados online da Biblioteca Virtual em Saúde (BVS), Google acadêmico, periódicos CAPES, base de dados MISSOC - Mutual Information System on Social Protection, OCDE, ILO e CEPAL. Os dados estatísticos utilizados foram obtidos das bases da OCDE e da Pordata (baseada no Eurostat), Banco Mundial (The World Bank Data), além da Secretaria do Tesouro Nacional. Como resultados encontrei uma disparidade entre os 2 países analisados quanto: a licença parental - ausente no Brasil, e a política de creches na Dinamarca ­ universal a partir de 26 semanas de vida onde os profissionais possuem expertise para atuarem com crianças pequenas nas creches e jardins de infância. (AU)

The Welfare State is the result of a historical, economic, political and social evolution, and depending on the regime in each country, there will be more comprehensive social policies than others. These policies provide a set of guarantees needed to reduce the distortions caused by the capitalist industrial model that emerged in Europe at the end of the 19th century. Among the most successful examples is the Danish system, which is highlighted in this article for reflecting the most complete and efficient family leave system, capable of guaranteeing universal access to mothers and their young children, minimizing social stratification and the commodification of social guarantees. Brazil is far from this reality, but after 1930 it began to develop a series of social policies which, since the 1988 Federal Constitution, have been universal in nature. The purpose of this research is to compare social policies aimed at families with young children in Brazil and Denmark, with the aim of analyzing the contribution of Brazilian social policies to overcoming gender inequality, promoting women's citizenship and children's development. The analysis focused on the regulation of maternity, paternity, and parental leave; the subsidies granted to families with young children and the nursery policy of the two countries. The methodology used was based mainly on a bibliographic and legislative review, using as a secondary source the online database of the Virtual Health Library (VHL), Google Scholar, CAPES journals, MISSOC database - Mutual Information System on Social Protection, ILO and CEPAL. The statistical data used was obtained from the OECD and Pordata databases (based on Eurostat), World Bank (The World Bank Data) and National Treasury Secretary of Brazil. As a result, I found a disparity between the two countries analyzed in terms of: parental leave - absent in Brazil and the nursery policy in Denmark - universal from 26 weeks of age where professionals have the expertise to work with young children in day care centers and nurseries. (AU)

Effect of prevalence of alcohol consumption and tobacco use in Mexican municipalities on early childhood development / Efecto de la prevalencia del consumo de alcohol y tabaco en municipios mexicanos sobre el desarrollo durante la primera infancia / Efeito da prevalência do consumo de álcool e tabaco em municípios mexicanos sobre o desenvolvimento durante a primeira infância

Abstract: One of the most critical time periods in childhood is from birth to five years of age. Children exposed to alcohol and/or tobacco via family members and neighborhood are at risk for childhood developmental delays. This study evaluated the association of early childhood development with the prevalence of alcohol consumption and tobacco use in Mexican municipalities. This is a cross-sectional study. Early childhood development information from 2,345 children aged from 36 to 59 months was obtained from the 2015 Mexican National Survey of Boys, Girls, and Women (ENIM). Data on alcohol consumption and tobacco use come from the 2016 Mexican National Survey on Drugs, Alcohol, and Tobacco Consumption (ENCODAT). Multilevel logistic models were fitted to evaluate the association of the prevalence of alcohol consumption and tobacco use with the inadequacy of early childhood development. Children living in municipalities with high prevalence of alcohol consumption (OR = 13.410; 95%CI: 2.986; 60.240) and tobacco use (OR = 15.080; 95%CI: 2.040; 111.400) were less likely to be developmentally on track regarding early childhood development after adjustment for individual variables related to the child's development and other environmental variables at municipal level. Childhood exposure to alcohol and tobacco in the neighborhood may directly contribute to inadequate early childhood development. These findings suggest that there is an urgent need to develop effective interventions aimed at reducing alcohol consumption and tobacco use in municipalities to ensure adequate early childhood development.

Resumen: El grupo de edad que se extiende desde el nacimiento hasta los 5 años es uno de los periodos más críticos en la infancia. Niños expuestos al alcohol y/o al tabaco a través de la familia y vecinos corren el riesgo de sufrir un retraso en el desarrollo infantil. Este estudio evaluó la asociación del desarrollo durante la primera infancia con la prevalencia del consumo de alcohol y tabaco en municipios mexicanos. Se trata de un estudio transversal. Las informaciones sobre el desarrollo durante la primera infancia de 2.345 niños de 36 a 59 meses se obtuvieron a través de la Encuesta Nacional de los Niños, Niñas y Mujeres en México (ENIM) de 2015. Los datos sobre el consumo de alcohol y tabaco son de la Encuesta Nacional de Consumo de Drogas, Alcohol y Tabaco en México (ENCODAT) de 2016. Se ajustaron los modelos logísticos multiniveles para evaluar la asociación de la prevalencia de consumo de alcohol y tabaquismo con desarrollo durante la primera infancia inadecuado. Los niños que viven en municipios que tienen una alta prevalencia de consumo de alcohol (OR = 13,410; IC95%: 2,986; 60,240) y tabaquismo (OR = 15,080; IC95%: 2,040; 111,400) se asociaron con la probabilidad más alta de tener un desarrollo durante la primera infancia inadecuado tras el ajuste de las variables individuales relacionadas al desarrollo del niño y a otras variables ambientales en nivel municipal. La exposición infantil al alcohol y al tabaco en la vecindad puede contribuir directamente a un desarrollo durante la primera infancia inadecuado. Estos hallazgos indican una necesidad urgente de desarrollar intervenciones eficaces destinadas a reducir el consumo de alcohol y tabaquismo en los municipios para asegurar un desarrollo durante la primera infancia adecuado.

Resumo: A faixa etária que se estende do nascimento aos 5 anos de idade é um dos períodos mais críticos na infância. Crianças expostas ao álcool e/ou tabaco por meio de familiares e vizinhos estão em risco de atraso no desenvolvimento infantil. Este estudo avaliou a associação do desenvolvimento durante a primeira infância com a prevalência do consumo de álcool e tabaco em municípios mexicanos. Trata-se de um estudo transversal. As informações sobre o desenvolvimento durante a primeira infância de 2.345 crianças de 36 a 59 meses foram obtidas pela Pesquisa Nacional Sobre Crianças e Mulheres no México (ENIM) de 2015. Os dados sobre consumo de álcool e tabaco são da Pesquisa Nacional sobre Consumo de Drogas, Álcool e Tabaco no México (ENCODAT) de 2016. Modelos logísticos multiníveis foram ajustados para avaliar a associação da prevalência de consumo de álcool e tabagismo com desenvolvimento durante a primeira infância inadequado. Crianças que vivem em municípios com alta prevalência de consumo de álcool (OR = 13,410; IC95%: 2,986; 60,240) e tabagismo (OR = 15,080; IC95%: 2,040; 111,400) foram associadas à maior probabilidade de ter um desenvolvimento durante a primeira infância inadequado após ajuste às variáveis individuais relacionadas ao desenvolvimento da criança e a outras variáveis ambientais em nível municipal. A exposição infantil ao álcool e tabaco na vizinhança pode contribuir diretamente para o desenvolvimento durante a primeira infância inadequado. Estas descobertas demonstram uma necessidade urgente de desenvolver intervenções eficazes destinadas a reduzir o consumo de álcool e tabagismo nos municípios para garantir um desenvolvimento durante a primeira infância adequado.

Benefícios previdenciários de pescadores artesanais e marisqueiras em comunidade quilombola no Nordeste do Brasil / Social security benefits for small-scale fisherman in a quilombola community in northeastern Brazil

Resumo Introdução: a pesca artesanal e a mariscagem são consideradas atividades especiais, para fins de benefícios, no âmbito do Regime Geral de Previdência Social do Brasil. Objetivo: descrever o acesso aos benefícios previdenciários por uma população quilombola tradicional pesqueira no Nordeste do Brasil, cuja principal atividade ocupacional é a extração e beneficiamento de mariscos. Métodos: estudo transversal, descritivo, em uma comunidade da Ilha da Maré, em Salvador, Bahia, Brasil. Os dados foram coletados por meio de entrevistas, utilizando questionários padronizados. Resultados: participaram 213 pescadores artesanais e marisqueiras, 76,5% do sexo feminino. Dentre os participantes, 62,9% não recebem nenhum tipo de benefício previdenciário. Apesar de se submeter a uma jornada de trabalho exaustiva (90,9%), com exposição a substâncias químicas (83,9%), ruído (69,9%) e radiação solar (88,2%), a maioria não obtém rendimentos que garantam a subsistência familiar (79,6%). Conclusão: há um importante déficit no recebimento de benefícios previdenciários em uma população quilombola tradicional que atende aos critérios de segurados especiais. Sugere-se adequação da legislação, de forma que o acesso aos benefícios se torne mais justo para as comunidades tradicionais.

Abstract Introduction: artisanal fishing and shellfish gathering are considered special activities under the Brazilian general social security system for the purposes of social security benefits. Objective: to describe the access to social security benefits for a traditional fishing quilombola community in northeastern Brazil, whose main occupational activity is shellfish extraction and processing. Methods: a cross-sectional descriptive study conducted in a community from Ilha da Maré, Salvador, Bahia, Brazil. Results: 213 fishermen (76.5% female) participated in the study, of which 62.9% did not receive social benefits. Although most participants undergoing an exhausting working hours (90.9%), with exposure to chemicals (83.9%), noise (69.9%) and solar radiation (88.2%), the majority of them do not earn an income that guarantees their family's subsistence (79.6%). Conclusion: there is an important deficit in social security benefits access for a traditional quilombola population that meets the criteria for special insurance. Legislation must be adapted to ensure fairer access to social benefits for this population.

Oral Health-Related Quality of Life among Children Aged 11-14 Years Old with and without Parental Care in South-East of Iran

ABSTRACT Objective: To measure the Oral Health-Related Quality of Life (OHRQoL) and compare children with and without parental care. Material and Methods: This cross-sectional study was conducted on 160 schoolchildren with parental care and 100 orphans in Kerman, Iran. After fulfilling the questionnaire voluntarily, a clinical examination was performed, and indices such as decayed, missing, and filled teeth (DMFT), molar-incisor hypoplasia (MIH), modified gingival index (MGI), traumatic dental injury (TDI), and malocclusion were recorded. Data were statistically analyzed using SPSS version 25 via the ANOVA, Pearson's correlation coefficient test, Chi-Square test, and descriptive statistics. Results: Children without parents scored poorly for OHQRoL items compared to those with parents (p<0.001). DMFT was not significantly related to OHRQoL; however, missing teeth were correlated with the CPQ11-14 overall. Also, the TDI index had a significant relationship with CPQ mean score (p=0.02). Moreover, the difference in the mean CPQ11-14 score in children with TDI in the two groups was significant regarding the quality of life (0.031). Conclusion: OHRQoL differed significantly between children in the two groups, which can be influenced by gender and habits. Due to the vulnerability of welfare-supported children without parental care, these findings emphasize the value of preventive and health-promoting measures for this group of children.

Ethical problems and solutions of experimental animals in functional experiment teaching / 中华医学教育探索杂志

Objective:To investigate the ethics and existing problems of experimental animals in medical experiments and experimental teaching, and to formulate countermeasures so that animal ethics and animal welfare can be truly reflected in medical experiments.Methods:In this study, a "Basic Function Experiment Center Animal Experiment Questionnaire" with 25 questions was formulated from three aspects: the ethical cognition of experimental animals, whether animal experiments are ethical or not, how to view the problems of animal ethics and experimental teaching and the cognition of virtual simulation experiment teaching. Questionnaire was sent to Hubei University of Medicine to investigate the international students of Batch 2017 (5-year program), undergraduates of Batch 2017 (5-year program) and nursing students of Batch 2018 (4-year program) as well as teachers, researchers and employees of laboratory animal center (all with bachelor degree or above). The survey results were expressed as percentage.Results:The recovery rate of the questionnaire in this study was 98.04%(2 451/2 500), among which the practitioners, teachers and researchers in the laboratory animal center clearly understood the ethics of experimental animals, but there was a widespread phenomenon of lagging ethics among the students. For example, 16.24% (398/2 451) students had not received animal experiment ethics education and training, 29.46% (722/2 451) were not clear about animal protection laws and regulations, 7.14% (175/2 451) thought animal experiments were immoral; 29.54% (724/2 451) had vague cognition of animal welfare and ethical knowledge; 25.91% (635/2 451) were not familiar with the operation steps; 9.38% (230/2 451) were indifferent to the extra treatment of animals due to operation errors, 7.83% (192/2 451) chose to give up the experiment in the treatment of animals after massive bleeding, only 5.43% (133/2 451) chose to continue the experiment after timely hemostasis and infusion, and 9.26% (227/2 451) chose to do operations unrelated to the experiment. After the experiment, 2.28% (56/2 451) chose to kill the animals by bloodletting, only 5.51% (135/2 451) chose excessive anesthesia euthanasia, and 1.96% (48/2 451) chose to kill the animals by cervical dislocation and violence. Only 15.79% (387/2 451) chose to remember the dead animal for 2 minutes. Only 32.56%(798/2 451) of the respondents understood virtual simulation experiment, 34.92% (856/2 451) of the respondents thought that virtual simulation experiment or experimental teaching video could be used to replace the existing live animal experiment, 77.56% (1 901/2 451) believed that the construction of virtual simulation laboratory should be strengthened.Conclusion:It is imperative to strengthen the education of students' ethics of experimental animals, which is conducive to the establishment of correct ethics of experimental animals for medical students, so that the "3R" principle and animal welfare can be truly implemented in experimental teaching and scientific research experiments.