Meta-analysis of Ganmao Qingre Granules in treatment of children with wind-cold syndrome / 中国中药杂志

To systematically evaluate the efficacy and safety of Ganmao Qingre Granules in treatment of children with wind-cold syndrome. The study systematically retrieved CNKI, WanFang, VIP, CBM, PubMed, EMbase and Cochrane Library for children cases with wind-cold syndrome treated with RCT. The literature inclusion criteria provided by Cochrane was used to evaluate the litera-ture quality, and Meta-analysis was conducted by RevMan 5.3 software. A total of 6 literatures were included, with a total sample size of 492 cases, including 246 cases in the experimental group and 246 cases in the control group. According to the results of Meta-analysis, the experimental group recorded the hypothermia time(MD=-0.38, 95%CI[-0.53,-0.23], P<0.01), the total clinical effective rate(RR=1.25, 95%CI[1.15, 1.36], P<0.01), the cough relief time(MD=-2.75, 95%CI[-3.05,-2.46], P<0.01), the decrease nasal congestion relief time(MD=-1.45, 95%CI[-1.69,-1.22], P<0.01), traditional Chinese medicine syndrome score(MD=-8.35, 95%CI[-9.35,-7.36], P<0.01), all of them were superior to those of the control group(Aminophenol Huangnamin Granules), with statistically significant differences. Only 2 literatures mentioned no obvious adverse reaction, and the other 4 literatures did not mention any adverse reactions. Based on the results of this study, it was indicated that Ganmao Qingre Granules were effective in the treatment of children with wind-cold syndrome, but with unclear adverse reactions. Due to the insufficient quantity and low quality of included literatures, the efficacy and safety need to be further confirmed by more high-quality clinical studies.

Therapeutic Observation of Moxibustion plus Cupping for Trigeminal Neuralgia Due to Wind-cold / 上海针灸杂志

To observe the clinical efficacy of moxibustion plus cupping in treating trigeminal neuralgia due to wind-cold.Method Seventy patients with trigeminal neuralgia due to wind-cold were randomized into a treatment group and a control group, 35 cases in each group. The treatment group was intervened by moxibustion plus cupping, while the control group was by ordinary acupuncture. The Visual Analogue Scale (VAS) and other pain indexes were observed before treatment and after 2 treatment courses, and the clinical efficacies were compared.Result The total effective rate was 85.7% in the treatment group versus 57.1% in the control group, and the difference was statistically significant (P<0.05). The VAS scores were significantly changed after treatment in both groups (P<0.01). After treatment, the VAS score of the treatment group was significantly different from that of the control group (P<0.01). After intervention, the scores of pain range, pain intensity, pain duration, attack frequency, quality of life, affection, and global pain score in the treatment group were significantly different from that in the control group (P<0.05).Conclusion Moxibustion plus cupping is an effective approach in treating trigeminal neuralgia due to wind-cold.