The design and clinical application of a new type of disposable heparin free dialysis tube / 中国实用护理杂志

Objective To investigate the clinical effect of a new type of disposable heparin freedialysis tube in uremic patients without heparin dialysis. Methods A total of 110 patients withoutheparin dialysis were divided into control group and observation group by random digits table method with55 cases each. Based on the same pre dialysis and dialysis for heparin saline flushing of discontinuoussaline on the control group using the traditional dialysis pipe for hemodialysis without heparin, theobservation group used disposable non heparin dialysis pipe for hemodialysis without heparin. The numberof patients with venous catheter blockage, blood loss and completion of dialysis time in two groups wasrecorded. Results The number of patients with venous catheter blockage, blood loss and completion ofdialysis time was 6, 6, 47 cases in control group and 0, 0, 54 cases in observation group. The differences were statistically significant (χ2=4.407, 4.407, 4.356, P<0.05). Conclusions The new disposableheparin free dialysis tube can reduce the loss of blood and prolong the treatment time, and the operation issimple, safe and effective, and has good application value and application prospect.

Clinical evaluation of anticoagulation without heparin during continuous venovenous hemofiltration / 中国实用内科杂志

Objective To evaluate anticoagulation without heparin during continuous venovenous hemofiltration.Methods From January to April of 2005,forty-two critically ill patients by therapy of continuous venovenous hemofiltration(CVVH)were enrolled in our study.Nineteen patients with high risk of bleeding who had received anticoagulation without heparin were as observation group,and the rest of the patients who had received anticoagulation with low molecular weight heparin were as control group.In the two groups,the replacement fluid rate was 3 000 mL/h;the therapy time was 12 hours/day;the bicarbonate replacement fluid were infused by the mode of predilution.Results The serum level of urea and creatinine were significantly decreased after treatment in the two groups,but there were no difference in the decrease of solution between the two groups.APTT was significantly extended in control group(P