Optimization of extraction process of Modified Yangyin Qingfei Decoction by Box-Behnken response surface methodology based on analytic hierarchy process / 中草药

Objective: To optimize the extraction process of Modified Yangyin Qingfei Decoction (MYQD). Methods: The effects of ethanol concentration, extraction time and extraction times on the optimization of extraction process of MYQD were investigated by multiple indicators comprehensive scoring and Box-Behnken response surface methodology. The content of verbascoside, chlorogenic acid, paeonol, and glycyrrhizic acid was simultaneously determined by HPLC, and the method of analytic hierarchy process was used to calculate the weight coefficient. Results: The optimum extraction process was as follow: using 69% ethanol for once extraction for 68 min. Conclusion: The optimum extraction process is simple and feasible, and the extraction efficiency of components is high, which can provide reference for the extraction process of MYQD.

The Study on Treatment of Laryngeal Cough with Yangyin Qingfei Decoction / 国际中医中药杂志

Objectjve To observe clinical efficacy of Yangyin Qingfei Decoction on laryngeal cough.Methods 127 cases with laryngeal cough were randomly divided into a treatment group and a control group.The treatment group was treated with Yangyin Qingfei Decoction and the control group was treated with Lanqing oral solution.Both groups were treated for a course of treatment of 7 days.Results The total effective rate of was 87.69%and 58.46%in the treatment group and the control group respectively,showing significant difference(P＜0.05).Conclusion Yangyin Qingfei Decoction is effective in treating laryngeal cough.