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Introduction. The acute coronary disease (ACD), broadly encompass the clinical states unstable angina (UA) and acute myocardial infarction (AMI), especially affects adults due to cause the impairment of work ability, associates reducement of life quality and high expenses of medical treatment, and induces leading cause of sever complication and death.Materials and Methods. In this study, 44 ACD patients and 33 healthy subjects enrolled into case and control group, respectively. Relationships of primary and intermediate risk factors between cases and healthy subjects were determined by questionnaire research and clinical examinations. Measurements such as C reactive protein (CRP), cholesterol, triglycerides, low-density lipoprotein (LDH), high-density lipoprotein (HDL), trooping I, and mean platelet volume (MPV) were analyzed by clinical laboratory assays. The SPSS12 statistical software was used for all statistical calculations.Results. Statistical significant differences of hypertension and smoking were observed in ACD patients (UA and AMI) (P<0.01) compared with healthy subjects by independent samples T test. Body mass (BM), waist-to-hip ratio (WHR), body mass index (BMI) were significantly different in patients with UA, but WHR, hip were significantly different in patients with AMI. The levels of biochemical measurements such as cholesterol, triglycerides, and glucose were significantly higher in patients with AMI (р<0.01), whereas glucose concentration was significantly higher in patients with UA (р<0.05). However, a kind of inflammatory markers, CRP was a risk factor in the patients with ACD (UA and AMI), whereas MPV was a risk factor for AMI only. In the ANOVA test, which was confirming analysis on the results of independent samples Ttest, overweight (BM), abdominal obesity (WHR, hip) measurements, parameter of glucose metabolism(glucose) and some inflammatory markers (CRP, MPV) were significantly different between study groups. Relationships by determined Pierson`s correlation, were observed between overweight parameters (BM, BMI) and biomarkers of fatty acid metabolism (cholesterol, LDL, HDL, triglycerides). The BM of overweight parameters and the WHR of abdominal obesity measurements were strongly associated with increased level of glucose.Conclusion. Primary risk factors including hypertension and smoking; parameters of the overweight or abdominal obesity such as BM, WHR, BMI and hip; biochemical measurements as cholesterol, triglycerides and glucose; and some inflammatory biomarkers as well as CRP and MPV were risk factors in the ACD.
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Objective To explore the clinical feature of acute coronary syndromes (ACS) in senior populations and provide reference for the clinical diagnosis and treatment. Methods Clinical data of 175 elder patients of ACS and 65 non-elder patients of ACS were collected from September,2006 to September,2009. Clinical data were compared between the two groups. Results The elder ACS patients had higher prevalence of hypertension,cerebro-vascular disorder and renal inadequacy (68.6%, 18.3% and 32.6%, respectively) than those in the non-elder ACS patients (46.2% ,3.1% and 10.8%, respectively) (P<0.01). The level of hemoglobin, cholesterol, LDL and tri-glyceride in the elder ACS patients ((120.93±30.02) g/L, (4.47±1.29) mmol/L, (2.42±1.05) mmol/L and (1.31±0.87)mmol/L,respectively) were lower than those in the non-elder ACS patients ((141.02±17.16)g/L, (4.98±1.01 ) mmol/L, (2.71±0.99) mmol/L and (1.78±1.2) mmol/L, respectively) (P<0.01, P<0.05). However,the level of fibrinogen was higher in the elder ACS patients ((381.01±150.94) μg/L vs ( 338.91± 138.65) μg/L , P<0.05). Conclusions Hypertension, cerebrovascular disorder, hypohemoglobinemia and renal inadequacy are highly correlated with ACS in senior populations. These factors should be considered in chnical diag-nosis and treatment. Early diagnose and treatment in time may decline the case-fatality rate.