New Advances, Challenges and Opportunities in Forensic Applications of Microbiomics / 法医学杂志

The succession of microbiota is closely associated with several essential factors, including race, sex, health condition, lifestyle, postmortem interval, etc., and it has great potential application value in forensic medicine. This paper summarizes recent studies on the forensic applications of the microbiome, including individual identification, geographical feature identification, origin identification of the tissue or body fluid, and postmortem interval estimation, and introduces the current machine learning algorithms for microbiology research based on next-generation sequencing data. In addition, the current problems facing forensic microbiomics such as the extraction and preservation of samples, construction of standardization and database, ethical review and practical applicability are discussed. Future multi-omics studies are expected to explore micro ecosystems from a comprehensive and dynamic perspective, to promote the development of forensic microbiomics application.

Analysis on characteristics of 8 670 dead inpatients in Affiliated Hospital of Southwest Medical University / 重庆医学

Objective To understand the disease distribution and change rule of death causes by analyzing 8 670 dead cases in the First Affiliated Hospital of Southwest Medical University during Juhuary 1,2000 to December 31,2014.Methods The disease classification in 2000 and 2001 adopted the ICD-9 as the standard,which in other years adopted the ICD-10 as the standard.The medical records of dead hospitalized cases in our hospital during Juhuary 1,2000 to December 31,2014 were retrospectively analyzed by using the Excel 2007,SPSS17.0 software system.Results The sex ratio of male and female mortality was about 1.92 ∶ 1 in these 15 years,the sex ratio of heart disease death was 1.3 ∶ 1.In these 15 years,the number of hospitalized patients was increased rapidly,while the mortality rate was declined year by year.The age group of high mortality rate was 60 years old and over(4 281 cases),accounting for 49.38％.Especially heart disease patients over 60 years old accounted for 61.9％of total heart disease deaths.Followed by the age group of 45-59 years old,accounting for 20.30％.The top three causes of death were circulatory system diseases,respiratory diseases and malignant tumors.The top three causes of death in circulatory system diseases were coronary heart disease,cerebral hemorrhage and cerebral infarction.The top three causes of cardiovascular system were coronary heart disease,high blood pressure and congenital heart disease.The top three causes of respiratory disease were pneumonia,chronic obstructive pulmonary disease and respiratory failure.The top three death causes of malignant tumor were lung cancer,leukemia and liver cancer.According to the seasonal distribution,the number of deaths in winter was up to 2 362 cases,the constituent ratio was 27.24 ％.Hospitalization days,the number of hospitalization death≤1 d was up to 2 625 cases,the constituent ratio was 30.28％.Conclusion Analyzing the death causes,disease distribution and change trend of inpatients is conducive to the rational allocationof medical resources,promote the reform of hospital management programs and improve the level of clinical epidemiological research in this area.

Death Causes of 16 Patients with Acute Myocardium Infarction / 中国康复理论与实践

@#ObjectiveTo analyze the death causes of acute myocardium infarction (AMI) and nursing measures.MethodsThe data of 16 AMI patients, 58～87 years old and died in the hospital, were analyzed for factors of direct death causes, inducement, death period.ResultsIn 16 patients, 13 cases died from heart reason, seven patients (43.75%) had inducements, 12 cases died in acute stege.ConclusionThe death cause of AMI is mainly heart reason, and related with basic disease and complication.