Paired logistic regression analysis of influencing factors for vascular crisis after repair of oral and maxillofacial tumors with free tissue flaps / 口腔疾病防治

Objective @#To investigate the influencing factors of vascular crisis after oral and maxillofacial tumor free tissue flap transplantation. @*Methods @# A retrospective analysis was performed on all patients who underwent free tissue flap transplantation and developed vascular crisis in the surgical ward of head and neck cancer in a grade A specialized hospital. Forty-six possible influencing factors were collected using 1:1 matching according to surgeons, operation time, sex and age of patients from patients without vascular crisis from 2015-2020 in this ward during the same period. SPSS 26.0 statistical software was used for univariate and multivariate logistic regression analyses of the data.@*Results @#A total of 158 patients were enrolled, including 79 in the crisis group and 79 in the pairing group. Univariate analysis was performed for each variable. Paired logistic regression analysis showed that only postoperative blood potassium (P = 0.048, OR = 3.118, 95% CI: 1.008-9.641) and preoperative and postoperative red blood cell count differences (P = 0.004, OR = 4.53, 95% CI: 1.609-12.750) were statistically significant.@*Conclusion @#High blood potassium levels and red blood cell count differences before and after surgery were risk factors for vascular crisis.

GG Genotype at rs1275988 and rs2586886 Loci of TWIK-related Acid-sensitive K Channel-1 Gene is A Potential Risk Factor for Severe Obstructive Sleep Apnea / 中国医学科学院学报

To explore the mechanism of obstructive sleep apnea(OSA) by assessing the association between human TWIK-related acid-sensitive K channel-1(TASK-1) gene and OSA. A total of 164 patients with severe OSA and 171 patients without OSA were recruited from the Hypertension Center of People's Hospital of Xinjiang Uygur Autonomous Region,China,from April to December 2016.Two single nucleotide polymorphisms(rs1275988 and rs2586886) in the TASK-1 gene were selected and genotyped using a Kompetitive Allele Specific PCR genotyping system. In patients with blood potassium 3.95 mmol/L in patients with TASK-1 GG genotype may be conducive to reducing the incidence of severe OSA.

The influence of blood sample placing time on the results of clinical biochemistry test / 中国生化药物杂志

Objective To analyze relevant mechanism of clinical biochemical test results with blood specimen placement time,and provide reference for clinical examination.Methods100 biochemical test specimen in our hospital were selected, Biochemical test data were analyzed at different storage time (1h, 3h, 6h, 24h) using automatic biochemical analyzer combined with electrolyte analyzer.ResultsThe results of blood 1H determination were taken as the test standard, and the blood samples were placed in 3h.The results showed that the contents of glucose and carbon dioxide were significantly decreased (P<0.05).Blood samples were placed 8h, serum potassium, glucose, carbon dioxide, alanine aminotransferase (P<0.05) were significant differences, blood specimens were placed 24h, there were significant differences of the indexes including blood glucose, potassium, carbon dioxide, alanine aminotransferase, alkaline phosphatase, total bilirubin, total protein, albumin, aspartate aminotransferase, serum potassium, alpha hydroxybutyrate dehydrogenase, lactate dehydrogenase (P<0.05).ConclusionThe blood sample placement time have a significant impact on some biochemical indicators, in view of the unstable factors should be detected in the blood sample 1h intact, to avoid delay condition assessment.

Application value of standard curve of K+ concentration in dialysis solution in personalized dialysis therapy / 医疗卫生装备

Objective To investigate the linear relationship and standard curve equation between acidic concentrated solution added KCl and the changes of K+ concentration in dialysate,and to apply it in personalized dialysis.Methods The speed of concentrated liquid pump of Fresenius 4008S hemodialysis machine was calibrated,the ratio of the concentration solution to the reverse osmosis water was determined,KCl was added to the concentrated A solution by an equal increment method to detect K+ concentration in the corresponding dialysate,and the K+ concentration standard curve of dialysate was mapped.This study is based on blood K+ concentration of adams-stokes syndrome patients before dialysis,referring to the standard curve,the most suitable dialysate K+ concentration was selected to personalized dialysis,the blood K+ concentration of the patients was measured after dialysis,and ECG monitoring and clinical symptoms observation were carried out.Results There was a linear relationship between acidic concentrated solution added KCl and the changes of K+ concentration in dialysate,the curve equation was y =0.384 lx + 0.002 3,R2 =0.999 4.There was no obvious change in the concentration of other electrolyte ions in the dialysate.Referring to the standard curve,the concentration of dialysate K+ could be adjusted accurately.The blood K+ concentration of adams-stokes syndrome patients could be corrected in time after several times of K+ concentration of personalized dialysis,and ECG recovered eventually,and arrhythmia,syncope,chest tightness and other symptoms disappeared.Conclusion There is a linear relationship between the concentration of dialysate K + and the concentration of KCl added in acidic concentrated solution in the Fresenius 4008S hemodialysis machine.Personalized dialysis is performed by the standard curve with obvious clinical application value,and references are provided for precise regulation of dialysate ion concentration.

Application value of standard curve of K+ concentration in dialysis solution in personalized dialysis therapy / 医疗卫生装备

Objective To investigate the linear relationship and standard curve equation between acidic concentrated solution added KCl and the changes of K+ concentration in dialysate,and to apply it in personalized dialysis.Methods The speed of concentrated liquid pump of Fresenius 4008S hemodialysis machine was calibrated,the ratio of the concentration solution to the reverse osmosis water was determined,KCl was added to the concentrated A solution by an equal increment method to detect K+ concentration in the corresponding dialysate,and the K+ concentration standard curve of dialysate was mapped.This study is based on blood K+ concentration of adams-stokes syndrome patients before dialysis,referring to the standard curve,the most suitable dialysate K+ concentration was selected to personalized dialysis,the blood K+ concentration of the patients was measured after dialysis,and ECG monitoring and clinical symptoms observation were carried out.Results There was a linear relationship between acidic concentrated solution added KCl and the changes of K+ concentration in dialysate,the curve equation was y =0.384 lx + 0.002 3,R2 =0.999 4.There was no obvious change in the concentration of other electrolyte ions in the dialysate.Referring to the standard curve,the concentration of dialysate K+ could be adjusted accurately.The blood K+ concentration of adams-stokes syndrome patients could be corrected in time after several times of K+ concentration of personalized dialysis,and ECG recovered eventually,and arrhythmia,syncope,chest tightness and other symptoms disappeared.Conclusion There is a linear relationship between the concentration of dialysate K + and the concentration of KCl added in acidic concentrated solution in the Fresenius 4008S hemodialysis machine.Personalized dialysis is performed by the standard curve with obvious clinical application value,and references are provided for precise regulation of dialysate ion concentration.

Clinical value of ECG in diagnosis of low blood potassium / 中国基层医药

Objective To investigate the clinical diagnostic value of electrocardiogram(ECG)in patients with low blood potassium.Methods From January 2015 to October 2015,patients with low blood potassium were given ECG examination in Yueqing Maternal And Child Health Care Hospital.The relationship between low blood potassium and ECG changes was analyzed.Results The concentration of serum potassium in patients with 0.9 -2.5mmol/L electrocardiogram U wave change,T wave change,ST segment changes,Q -T prolongation,arrhythmia were significantly higher than that of serum potassium concentration in 2.6 -3.4mmol/L patients,and the difference was statistically significant (χ2 =4.63,4.10,4.47,5.01,4.92,all P <0.05).Of patients with hypokalemic ECG showed characteristics of U wave amplitude increased,ST segment depression,T wave amplitude decreased,QT interval prolongation,arrhythmia,of which the most common was premature ventricular contractions,severe low blood potassium could also be occurrence of malignant ventricular arrhythmia.Conclusion Low blood potassium has characteristic changes of ECG,ECG as a noninvasive,simple and quick examination,which is helpful for the rapid diagnosis of low blood potassium.

Analysis on the factors influencing the serum potassium concentration changes before and after massive blood transfusion and transfusion hyperkalemia occurred / 中国医学装备

Objective: To study the changes of blood transfusion and blood potassium concentration and the occurrence of hyperkalemia after transfusion factors influence. Methods: In our hospital from 2010 April to select the diagnosis and treatment of -2012 in April 132 cases of non crush injury patients, these patients were randomly divided into two groups, the control group without blood transfusion therapy group, the observation group for massive transfusion treatment group, changes of serum potassium were compared between the two groups before and after transfusion, and to analyze the related effect factors. Results:The serum potassium levels showed no significant difference between the two groups of patients before and after blood transfusion, operation process, but the postoperative within 12h, observation of blood potassium level group were significantly higher than that in control group, the difference is significant, with statistical significance (t=1.562, P<0.05), in addition to 12h after operation, blood potassium levels between the two groups no significant difference. Conclusion: The clinical blood transfusion is not the main cause of hyperkalemia in patients with, but there are still some patients in massive transfusion potassium increased, therefore, in the process of transfusion, or to close monitoring and observation of the serum potassium level, but also to pay attention to changes in renal function, has ruled out the elevation of serum potassium results in impaired renal function because, in order to reduce the incidence of complications.

Rocuronium Pretreatment for Prevention of Myalgia Following Succinylcholine Administration / 대한마취과학회지

BACKGROUND: The purpose of this study was to assess the effect of rocuronium pretreatment on the succinylcholine induced biochemical changes and fasciculations, myalgia and to compare it with vecuronium pretreatment. METHODS: We have studied 60 patients undergoing minor elective surgery, in a prospective double blinded method. Three groups of 20 patients each were pretreated with saline 0.01 ml/kg (group C), rocuronium 0.05 mg/kg (group R), or vecuronium 0.007 mg/kg (group V). Three minutes after the pretreatment, 1.5 mg/kg succinylcholine was injected. Serum potassium five minutes after succinylcholine and creatine kinase 24 hr after operation were measured. Fasciculations and postoperative myalgia at 24 and 48 h were evaluated. RESULTS: The increase in creatine kinase and incidence of fasciculations were lowest in the rocuronium group (33 IU/L; 15%) and followed by vecuronium group (58 IU/L; 50%) and highest in the control group (101 IU/L; 100%). The increase in serum potassium concentration (0.3 mEq/L) was not attenuated by any regimen. The incidence of postoperative myalgia on day 1 and day 2 was lower in the rocuronium (40%, 30%) and the vecuronium (50%; 35%) group than control group (85%; 75%). CONCLUSIONS: Rocuronium pretreatment is more effective in reducing creatine kinase rise and fasciculations after succinylcholine than vecuronium. However rocuronium and vecuronium are also effective in preventing postoperative myalgia.

Effect of Blood Surgar and potassium of An Intravenous Anesthetic Etomidate / 昆明医科大学学报

Blood sugar and potassium levels were mesured before and after intravenous injection of Etomidate to serve as an inducing agent in general anesthesea.The results showed that the blood potassinm in 31patients, the blood sugar in 29 patients were normal and had no statistical significance of difference.Hence the authors consider that Etomidate has neither influence on blood sugar nor on blood potassium.Etomidate is a safe, ideal intravenous anesthetic worthwhile to be recommended.