Analysis of the change of the saponins constituents in processed Radix Bupleuri / 中成药

AIM: Research on the change of the saponins constituents of Radix Bupleuri after being processed has been carried out. METHODS: Saikosaponin a、c、d and b2 are used as the marker ingredients; the change of saponins constituents,both after procession and saponated action,have been determined by HPLC. RESULTS: After being processed,the content of saikosaponin b2 has a significant increase,saikosaponin a,saikosaponin c,saikosaponin d and saikosaponin a + c + d all have slight decrease. After the saponated action,the content of saikosaponin a + c + d has a little change,and saikosaponin b2 has increased significantly. CONCLUSION: The change rules of saponin compounds in processed Radix Bupleuri have been revealed.