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Objective To explore the relationship between genital endocrine hormones and sleep disorder in climacteric depression,and study the therapeutical functions of Bushen Tiaogan Qingxin Prescription.Methods Sixty patients were randomly divided into Bushen Tiaogan Qingxin prescription group(n=30) and HRT group(n =30).The effects were appraised by both Hamilton depression rating scale(HAMD) and sleep disorder scores before and after the treatment of 12 weeks.The values of blood E2,FSH,LH were measured.Results Decreasing rate of HAMD and sleep disorder improving rate were significant in Bushen Tiaogan Qingxin prescription group than HRT group(P
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Objective: To investigate the morbidity of climacteric depression in Beijing area. Method: Among 18 districts and counties of Beijing area, using the stratified clustering and probability proportional method sampled 7232 women aged 40 to 65. The subjects completed Zung's self-rating depression scale, possible risk factors were also collected. Result: 6786 valid questionnaires were analyzed, among them, 223 suffered from climacteric depression (3.65%). The depressive symptoms had a significant positive correlation with the climacteric syndromes. Risk factors of depression included history of abortion or premature birth, duration of menopause, hypertension, bone fracture, smoking and incompatible with their husband. Family history of psychiatric illness had no influence in this study.Conclusion:Depression in climacteric women is not only a mental health problem, but also a biopsychosocial problem.