RESUMO
Zuotai(mercury preparation)is considered the treasure of Tibetan medicine and is commonly referred to as the"King of Medicines".It is widely utilized in clinical practice as a core ingredient in the precious Tibetan medicine compounds,which possesses multiple therapeutic properties such as disease treatment,detoxification,health maintenance,and tonic effect.This paper conducted a comprehensive review of the classical Tibetan medical literature and recent research literature to elucidate the historical development and modern applications of the"Zuotai"concoction method.There are three main representative approaches of Zuotai concoction,including the mercury concoction method in the"Four Medical Tantras"by Udo-Yundan Pao(708-833),the concoction method in the"Mercury Concoction Classics"by Dongshun Nu Gyatso(13th century),and the mercury concoction method by Master Tsuru Tsering(1926-2004),who has imparted the Zuotai concoction process since the establishment of New China.In addition,Zuotai has been extensively studied by researchers in the fields of modern pharmacochemistry,pharmacokinetics,and toxicology.Overall,this paper provides a comprehensive review of the concoction methods of"Zuotai"in the classical Tibetan medical literature and modern pharmacological and toxicological research,so as to provide important reference value for in-depth understanding of the origin and history of"Zuotai".
RESUMO
The solubility of calcium phosphate crystallization in vitroby an deproteinized concoction of Basella rubraplant was investigated by weight reduction assay. Soluble oxalate of the plant arepartially removed prior to extraction of plant material. The weight variation and dissolution results reveals that the concoction showed considerable increased activity at the highest concentration used. The results indicate that the calcium phosphate crystal inhibition activity exhibited by the plant material may be due to their calcium phosphate solubilising capacity of phytoconstituents present in them. Regular consumption of an concoction of our plant would be helpful in calculi prophylaxis