Bone/cartilage immunomodulating hydrogels: construction strategies and applications / 中国修复重建外科杂志

OBJECTIVE@#To review the research progress in the construction strategy and application of bone/cartilage immunomodulating hydrogels.@*METHODS@#The literature related to bone/cartilage immunomodulating hydrogels at home and abroad in recent years was reviewed and summarized from the immune response mechanism of different immune cells, the construction strategy of immunomodulating hydrogels, and their practical applications.@*RESULTS@#According to the immune response mechanism of different immune cells, the biological materials with immunoregulatory effect is designed, which can regulate the immune response of the body and thus promote the regeneration of bone/cartilage tissue. Immunomodulating hydrogels have good biocompatibility, adjustability, and multifunctionality. By regulating the physical and chemical properties of hydrogel and loading factors or cells, the immune system of the body can be purposively regulated, thus forming an immune microenvironment conducive to osteochondral regeneration.@*CONCLUSION@#Immunomodulating hydrogels can promote osteochondral repair by affecting the immunomodulation process of host organs or cells. It has shown a wide application prospect in the repair of osteochondral defects. However, more data support from basic and clinical experiments is needed for this material to further advance its clinical translation process.

Urban sports service structure from the public health context / Estrutura de serviços esportivos urbanos no contexto da saúde pública / Estructura de servicios deportivos urbanos en el contexto de la salud pública

ABSTRACT With the improvement of the quality of life, the residents' requirements for the construction of urban public sports services have gradually improved. In order to improve the current urban public sports service system, this study analyzes the existing public sports service through the construction of public sports service model. The results show that the current construction of public sports service has some defects, such as single construction subject, unbalanced regional development of sports service, lack of perfect performance evaluation mechanism of sports public service, and so on. Therefore, in the process of public sports service construction, we need to pay attention to the diversification of construction subjects, the cultivation of residents' awareness of physical exercise, the improvement of performance evaluation mechanisms of sports public services, and the broadening of investment channels. These measures can improve the urban public sports service system from the perspective of public health, and create better quality public sports services. This study analyzes the problems existing in the construction of public sports service by building a model, and puts forward some suggestions for improvement, hoping to provide ideas for scholars who study related experiments.

RESUMO Com a melhoria da qualidade de vida, os requisitos da população para a construção de serviços desportivos públicos urbanos melhoraram gradualmente. A fim de melhorar o atual sistema de serviço público de esportes urbanos, este estudo analisa o serviço público de esportes existente através da construção do modelo de serviço público de esportes. Os resultados mostram que a atual construção do serviço público de esportes tem alguns defeitos, como a questão da construção única, o desenvolvimento regional desequilibrado dos serviços de esportes, a falta de um mecanismo perfeito de avaliação do desempenho do serviço público de esportes e assim por diante. Por conseguinte, no processo de construção desses serviços, temos de prestar atenção à diversificação das disciplinas de construção, à cultura da conscientização da população para o exercício físico, à melhoria do mecanismo de avaliação do desempenho do serviço público de esportes e à expansão dos canais de investimento. Essas medidas podem melhorar o sistema de serviços públicos urbanos de esportes do ponto de vista da saúde pública e criar serviços desportivos públicos de maior qualidade. Este estudo analisa os problemas existentes na construção desses serviços através da construção de um modelo, e apresenta algumas sugestões para melhorias, esperando fornecer ideias para pesquisadores que estudam experimentos relacionados.

RESUMEN Con la mejora de la calidad de vida, se han ido mejorando paulatinamente las exigencias de la población para la construcción de servicios deportivos públicos urbanos. Con el fin de mejorar el actual sistema de servicios públicos deportivos urbanos, este estudio analiza el servicio público deportivo existente mediante la construcción de un modelo de servicio público deportivo. Los resultados muestran que la construcción actual del servicio público deportivo tiene algunos defectos, como el tema de construcción única, el desarrollo regional desequilibrado del servicio deportivo, la falta de un perfecto mecanismo de evaluación del desempeño del servicio público deportivo, etc. Por ello, en el proceso de construcción de los servicios públicos deportivos, es necesario prestar atención a la diversificación de los temas de construcción, el cultivo de la conciencia de la población sobre el ejercicio físico, la mejora de los mecanismos de evaluación del desempeño de los servicios públicos deportivos y la ampliación de los canales de inversión. Estas medidas pueden mejorar el sistema de servicios deportivos públicos urbanos desde la perspectiva de la salud pública y crear servicios deportivos públicos de mayor calidad. Este estudio analiza la problemática existente en la construcción del servicio público deportivo mediante la construcción de un modelo, y presenta algunas sugerencias de mejora, esperando brindar ideas para los académicos que estudian experimentos relacionados.

Construction strategy of medical resource integration in regional medical alliance based on grounded theory / 中华医院管理杂志

Objective:To explore the integration path of medical resources in regional medical consortium, find out the problems affecting the process of integration, and put forward relevant suggestions.Methods:Methods According to the purposive sampling and combined with grounded theoretical research methods, semi-structured interviews were conducted with 73 government officials, heads and backbones of medical institutions in different regions of a city from August to November 2019. The data obtained from semi-structured interviews were analyzed by using grounded theory, and the path framework of medical resource integration in regional medical consortium was constructed through open coding, spindle coding and selective coding.Results:Four key links of medical resource integration in the regional medical alliance were sorted out, namely, integration prerequisites, integration strategies, support conditions, and integration methods, which together constituted the main axis of the theoretical framework. In addition, integration methods were affected by integration prerequisites, integration strategies and support conditions. The four factors and integration willingness served as influencing factors to exert impact on the integration tendency.Conclusions:The integration of medical resources in the medical alliance is a systematic project, which emphasizes the organic and overall governance of each key link, and the interaction between various elements will affect the final effect of medical resource integration.

Construction strategy of nerve conduits bridging long peripheral nerve defects / 中国医师进修杂志

The repair, regeneration and functional recovery of peripheral nerve defects are the clinical problems needed to be solved urgently.Researches showed that the hollow conduits of bridging nerve defects only had the functions of support and isolation, but the composite conduits could simulate nerve regeneration microenvironment and possess biological activity, which could effectively guide the migration of Schwann cells and the regeneration of axons to achieve satisfactory effects of restoration and functional recovery.With the development of tissue engineering, regenerative medicine, biomaterial and the techniques of cells and molecular biology, the construction of biomimetic and functional nerve conduits to bridge long nerve defects has attracted more and more attention. This review will provide a brief overview of the construction strategy of nerve conduits repairing long nerve defects of peripheral nerves.

Construction of Curriculum System of Medical Humanity Based on the Quality Features of Famous Doctors / 中国医学伦理学

Objective:To discuss the structure of medical humanistic curriculum system based on the research of quality features of excellent doctors .Methods:The goal , content and form of humanistic curriculum were based the factor of famous doctors'competencies which was build on the basis of literature review and experts'interview. Results:Ability and attitude or values accounted for high proportion of overall quality features .Humanities con-tained in most factors of excellent doctors'quality features;guiding significance of the structure of medical humanis-tic curriculum system is provided with excellent doctors'quality features .Conclusion:We should focus on the inte-gration of humanistic knowledge and practice , push humanities course into every stage of the medical education , further enrich category and quantity of medical humanities course and teaching form of medical humanities course , perfect the examination mode of medical humanities course in order to cultivate more excellent doctors .