Diagnóstico y seguimiento de pacientes con sangre oculta positiva en heces fecales / Diagnosis and follow-up of patients with positive hidden blood in fecal feces

Introducción: la hemorragia digestiva se define como toda pérdida de sangre procedente de cualquier sitio del tubo digestivo, desde la boca hasta el ano, incluyendo las hemorragias digestivas originadas en órganos que drenan en la luz intestinal. Objetivo: realizar el diagnóstico y seguimiento de pacientes con sangre oculta positiva en heces fecales. Materiales y métodos: se realizó un estudio epidemiológico descriptivo en el municipio de Unión de Reyes, provincia de Matanzas, entre los años 2014-2015. El universo y muestra estuvo constituida por 130 pacientes a los cuales el test de sangre oculta en heces fecales fue positivo, teniendo entre las variables características sociodemográficas de los pacientes, diagnóstico y seguimiento. Resultados: dentro de los resultados obtenidos las edades comprendidas entre 50-69 años fueron las más frecuentes, así como el sexo femenino donde la positividad del test fue mayor al igual que en negros y mestizos. Los medicamentos que más incidencia tuvieron fueron los antiinflamatorios no esteroideos y la aspirina. El test le fue indicado a 115 pacientes por atención primaria siendo 76 por pesquisa. A 80 pacientes no se les comunicó con que intensión se indicaba el examen. Del total de pacientes 43 tuvieron enfermedades relacionadas con el tracto digestivo alto y 44 del bajo. Conclusiones: uno de cada cinco pacientes presentó alguna tumoración del tracto digestivo. Se consideró que el trabajo de los equipos de salud fue deficiente en el diagnóstico y seguimiento de los pacientes (AU).

Introduction: digestive hemorrhage is defined as any blood loss that stems from any site of the alimentary canal, from the mouth to the anus, including digestive hemorrhages occurring in organs draining in the intestinal lumen. Objective: to diagnose and follow-up patients with positive hidden blood in fecal feces. Materials and methods: a descriptive epidemiologic study was carried out in the municipality of Unión de Reyes, province of Matanzas, in the period 2014-2015. The universe and sample were formed by 130 patients whose test of hidden blood in fecal feces was positive, taking as variables the socio-demographic characteristics of the patients, their diagnosis and follow-up. Results: some of the obtained results were the predominance of ages between 50 and 69 years, and also the female sex with higher test positivity like in black and mestizo patients. The medications having more incidence were the non-steroidal antiinflammatory ones and aspirin. The test was indicated to 115 patient in the primary health care, being 76 in the screening. 80 patients were no informed of the intentionality when the test was indicated. From the total of the patients, 43 had diseases related with the upper digestive tract, and 44 with the low one. Conclusions: one form each five patients showed any tumor of vthe digestive tract. The work of the health teams was considered deficient in relation with the patients' diagnosis and follow-up...(AU)

Advances in Relationship Between the Number of Infiltrating Dendritic Cell and the Postoperative Prognosis of Digestive Malignant Tumor / 中国普外基础与临床杂志

Objective To study the advances in t he relationship between the number of infiltrating dendritic cells and the posto perative prognosis of digestive malignant tumor. Methods The literature in recent years on the rela tionship between the number of infiltrating dendritic cells and the postoperativ e prognosis of digestive malignant tumor was reviewed.Results The number of infiltrating dendritic cells among esophageal cancer,and gastric carcinoma,colonic cancer and pancreatic canc er was associated with a better prognosis.Conclusion The population density of dendritic cel ls among the malignant tissue could be regarded as an independent indicator in e stimating the postoperative prognosis of malignant tumor.

Advances in digestive tumor using SELDI-TOF-MS protochip technique / 肿瘤研究与临床

With the rapid development of proteomics technology,SELDI protein chip technology has become a powerful tool for proteomics with the capacity of gathering sample separation,purification,testing and data analysis together.As its convenience,high-throughput and high-sensitivity,as well as simple and fast analysis,SELDI technology plays an important role in the diagnosis and prevention of tumor.Here we re- view the basic principles,features and recent advances of this technology in digestive tumor.

Ultrasonic diagnosis of digestive tumor

A retrospective study on 40 cases of digestive tumor diagnosed by combination of ultrasound, X-ray and laparoscopy in which the ultrasound and anapathology play a role as screen has shown that the sensitivity and accuracy of ultrasound in the detection of digestive tumors was 97.05% and 87.50%, respectively. However, it should combine the ultrasound with other imaging diagnosis to obtain the higher accuracy

Advances in the research on relationship between p27Kip1 and digestive tumors / 中国癌症杂志

p27kip1 maps 12p13 and it has two exons. p27 not only inhibits the activation of acyclin dependent kinases, but also surpress the activity of ctivated cyclin CDKs. p27 plays a key role in the regulation of cell cycle progression, and relates to cell differentiation and apoptosis. Loss of p27 protein or lower level of it is prevalent in digestive tumors, and reduction of p27kip1 protein indicates malignant prognosis.