RESUMO
Objective::To explore the distribution characteristics of traditional Chinese medicine (TCM) syndromes of critical lesions of coronary heart disease, and determine the classification and diagnostic criteria of syndromes, so as to provide reference for the differentiation and treatment of this disease. Method::Totally 1 000 patients with critical lesions of coronary heart disease treated in the Department of Cardiology, Yunnan Provinceal Hospital of TCM from January 2016 to December 2018 were selected as the subjects by clinical epidemiological research methods. Basic information, diagnosis and treatment of the patients, as well as the information obtained through observation, hearing, inquiry and pulse-taking of TCM were collected. Symptoms, signs, tongue signs, pulse signs and other four diagnostic information, as well as relevant clinical data were collected for mathematical statistics analysis by cluster analysis and factor analysis research methods, and expert group opinions were also included in discussion. Result::First, the results of cluster analysis showed six types of basic TCM syndromes in accordance with the clinically actual critical lesions of coronary heart disease: blood stasis syndrome, phlegm turbidity syndrome, cold congealing heart pulse syndrome, Qi deficiency syndrome, heart-kidney Yin deficiency syndrome, Heart-Yang deficiency syndrome. Second, a factor analysis was carried out on the basis of cluster analysis, and the main syndromes of each basic syndromes were preliminarily determined. Third, because of the duplicate content or the unified combination of different syndromes, the TCM syndromes of the critical lesions of coronary heart disease can be summarized in five categories, namely phlegm turbidity and blood stasis syndrome (368 cases, 36.80%), cold congestion heart pulse syndrome (156 cases, 15.60%), Qi deficiency and blood stasis syndrome (315 cases, 31.50%), Yin deficiency of heart and kidney (91 cases, 9.10%) and Heart-Yang depression (70 cases, 7.00%). The main and secondary syndromes refer to factor analysis results of six basic syndromes. Conclusion::Cluster analysis and factor analysis can be made on TCM syndromes of critical lesions of coronary heart disease to pave the way for the classification of TCM syndromes and the establishment of diagnostic criteria of TCM syndromes of coronary heart disease, with an important clinical significance.
RESUMO
Objective@#To systematically search the related literature of dengue syndrome in recent years, so as to understand the traditional Chinese medicine (TCM) syndrome distribution of dengue fever.@*Methods@#China biomedical database, CNKI, VIP and Wanfang database were searched. The epidemiological studies on the TCM syndrome of dengue fever were enrolled. The first author of this study, sample size, diagnostic criteria and the syndrome differentiation were collected. SPSS 21.0 software was used to carry out frequency statistics, describe the distribution of common clinical syndromes of dengue fever, and count the number and percentage of patients corresponding to each syndrome type.@*Results@#A total of 12 articles were enrolled, including 2 639 patients. The number of male patients were much more than the females. Most of the patients came from Guangdong, mostly after the outbreak of dengue fever in Guangdong in 2014.The most common TCM syndrome types include both the defense and Qi phases (25.20%), damp heat repression (20.69%), blood stasis and toxin (16.37%), excess of Qi and heat (12.24%), vigorous heat at qi-blood phase (10.19%).@*Conclusions@#The main pathogenic factors of dengue fever are heat, humidity and toxicity. The most common syndromes are both the defense and Qi phases, damp heat repression and blood stasis and toxin.
RESUMO
Objective To systematically search the related literature of dengue syndrome in recent years, so as to understand the traditional Chinese medicine (TCM) syndrome distribution of dengue fever. Methods China biomedical database, CNKI, VIP and Wanfang database were searched. The epidemiological studies on the TCM syndrome of dengue fever were enrolled. The first author of this study, sample size, diagnostic criteria and the syndrome differentiation were collected. SPSS 21.0 software was used to carry out frequency statistics, describe the distribution of common clinical syndromes of dengue fever, and count the number and percentage of patients corresponding to each syndrome type. Results A total of 12 articles were enrolled, including 2 639 patients. The number of male patients were much more than the females. Most of the patients came from Guangdong, mostly after the outbreak of dengue fever in Guangdong in 2014.The most common TCM syndrome types include both the defense and Qi phases (25.20%), damp heat repression (20.69%), blood stasis and toxin (16.37%), excess of Qi and heat (12.24%), vigorous heat at qi-blood phase (10.19%). Conclusions The main pathogenic factors of dengue fever are heat, humidity and toxicity. The most common syndromes are both the defense and Qi phases, damp heat repression and blood stasis and toxin.
RESUMO
OBJECTIVE: To study the accumulation dynamics and distribution law of vitexin during the whole year period in different parts of Vitex negundo var.cannabifolia (Sieb. et Zucc.). METHODS: Vitexin was obtained by ultrasonic extraction, and its content was determined by HPLC. Filodoor column (4.6 mm×150 mm, 5 μm) was used. Methanol-water (volume ratio of 4;6) was used as the mobile phase at a flow rate of 1 mL·min-1. The UV detective wavelength was set at 340 nm, injection volume was 5 μL, and the column temperature was set at 35°C. RESULTS: The content of vitexin was low in vitex negundo branches and flowers, and had obvious regularity in different growth periods of Vitex negundo leaves. The content of vitexin was the highest (1.380%-1.465%) in June and July. Along with the blooming and formation of negundo chastetree to their maturation, the content of vitexin in Vitex negundo leaves decreased. Its content was the lowest (0.720%-0.751%) in September and October. The content of vitexin in Vitex negundo seeds increased(0.435%-1.231%)with seed maturation. CONCLUSION: The content of vitexin in different parts of Vitex negundo presents a regular change in different periods. The detection of vitexin in different growth periods provides experimental basis for the selection of best collection phase and medical parts.