An Immediately Accessible Search System for Interaction Information Using Databases from Both Japan and the United States: Construction and Application in Responding to Work-Related Questions / 医薬品情報学

<b>Objective: </b>When responding to questions regarding drug-drug interaction by the medical staff of our hospital, pharmacists previously collected information using some drug databases from Japan and the United States.  The aim of this study was to construct a search system for interaction information using drug databases from both Japan and the United States for streamlining questions and answers regarding drug-drug interaction.<br><b>Methods: </b>Using the drug databases from Japan and the United States, we collected information on the interaction pertaining to drugs prescribed at Kobe University Hospital.  This information was further assessed for consistency.  Furthermore, we constructed an original search system for interaction information for streamlining questions and answers regarding drug-drug interaction.<br><b>Results: </b>The difference between information obtained from the databases from Japan and the United States was apparent.  Thus, we concluded that it was necessary to obtain interaction information via a database search that included information from both the countries.  Therefore, our original interaction search system was reconstructed with interaction information collected using databases from both the countries.  We compared the response to questions regarding the previous and present methods using our original search system for interaction information; the time required to obtain the responses was 5.89 and 3.09 min, respectively, and it took lesser time for providing responses than the previous method.<br><b>Conclusion: </b>We evaluated the usefulness of the original search system for interaction information.  We found that the original system provides a more rapid response to questions compared with the previous method.  We are considering a further upgrade and update for the original system by adding information on drugs not prescribed by our hospital.

<b>Case-Control Study within a Cohort</b> / 薬剤疫学

In this article, we provide a brief summary of study design of case-control study within a cohort and an introduction of two case-control studies within a cohort conducted in Japan recently using antihypertensive drug database based on the post-marketing surveillance data of pharmaceutical companies. In the case-control study within a cohort, it is possible to avoid bias caused in a case-control study and conduct more efficiently than cohort study. Therefore the case-control study within a cohort widely has been used in pharmacoepidemiological studies with a database. (Jpn J Pharmacoepidemiol 2013; 18(2): 77-83)

Function of Drug Database Management Software Development System in Our Hospital / 中国药房

OBJECTIVE:To promote the computerized management of drug database.METHODS:The function of drug database software development system(SDS)developed by the co-efforts of pharmacy department and information center in our hospital was introduced.RESULTS:With hospital information system,the software can conduct statistics and queries of patients’drug database information at any time.CONCLUSION:The computerized management of drug database can provide prompt and efficient data support for rational drug administration and which is in the benefit of the development of clinical pharmacy work.