Infertilidade na endometriose: etiologia e terapêutica / Infertility in endometriosis: etiology and treatment

A endometriose consiste no alojamento de tecidos endometriais em certas regiões que ficam fora do útero. O número de casos dessa patologia é cada vez maior e é capaz de influenciar a fertilidade feminina. Os sinais e sintomas da patologia foram considerados no estudo, além de fatores biopsicossociais que envolvem as mulheres. Esse trabalho foi baseado em uma revisão bibliográfica a partir de uma seleção de artigos que relatam sobre endometriose e sobre a relação dessa enfermidade com infertilidade na população feminina. A partir da revisão de literatura, essa patologia pode causar modificação quimiotática e anatômica no aparelho de reprodução das mulheres, causando assim a infertilidade, dependendo do nível em que se encontra essa doença. Ademais, o tratamento dessa enfermidade, hormonal ou cirúrgico, é capaz de influenciar no processo saúde-doença da mulher, e ainda, possibilitar uma futura gravidez.

Endometriosis consists in endometrial tissues growth or adaptation outside of the uterus. The number of cases of this specific pathology has become more frequent and it may be capable influencing female fertility. Biopsychosocial factors as well as signs and symptoms that involve women are considered in this study. This work was based on a bibliographical review of selected articlesthat referred to endometriosis and its relationship with infertility in the female sex. According to this review, this pathology causes chemotactic and anatomic modification in the uterus, and consequently, infertility which depends on how advanced the disease is. Furthermore, the treatment of the disease, hormonal therapy or surgery, can influence the health-disease process as well as enable a future pregnancy.

Clinical impacts of laparoscopic surgery combined with GnRH-a on endometriosis infertility / 中国内镜杂志

Objective To discuss the clinical impact of laparoscopic surgery combined with GnRH-a for endometriosis infertility. Methods From June 2013 to June 2014, 88 endometriosis infertility patients were selected and divided into study group and the control group by the random number table method. The patients in study group were treated with laparoscopic surgery combined with GnRH-a. The patients in control group were treated with only laparoscopic surgery. The clinical efficacy, ovarian function and pregnancy outcomes of the patients in two groups were compared and analyzed. Results Compared with control group, the patients in study group, the clinical treatment for endometriosis achieved complete remission rate was 65.91 % (29/44) and total effective rate was 93.18 % (41/44), there were increased significantly, and the recurrence rate was 2.27 % (1/44), there was decreased significantly, after statistical analysis, the differences were significant statistically (P < 0.05). Compared with control group, the patients in study group after treatment, the level of E2 was (80.96 ± 17.65) ng/L, there were increased significantly, while the level of LH was (10.94 ± 3.20) IU/L and FSH was (6.24 ± 1.38) IU/L, there were decreased significantly, after statistical analysis, the differences were significant statistically (P < 0.05). Compared with control group, the patients in study group, the pregnancy rate was 47.73 % (21/44) and the living rate was 45.45 % (20/44), there were increased significantly, while the not pregnancy rate was 52.27 % (23/44), there was decreased significantly, after statistical analysis, the differences were significant statistically (P < 0.05). Conclusions Laparoscopic surgery combined with GnRH-a could improve the clinical efficacy of endometriosis infertility patients effectively, and further improve the ovarian function of patients, improve the pregnancy rate significantly.

Laparoscopic ventrohysteropexy in the treatment of endometriosis / 中国微创外科杂志

Objective To study the role of laparoscopic ventrohysteropexy in the treatment of endometriosis with a retroverted uterus. Methods 64 patients with endometriosis diagnosed under laparoscopy were retrospectively analyzed.After performing conservative operative procedures for the treatment of endometriosis,21 patients underwent ventrohysteropexy(group Ⅰ) and 43 patients didn't(groupⅡ). Results Follow-up study of the 64 cases for 2 to 6 years showed that (1)The complete relief rate of dysmenorrhoea was 94.1% and 87.5% in group Ⅰ and group Ⅱ,respectively.There was significant difference( ? 2=7.23, P