RESUMO
Objective To evaluate insulin resistance and ?-cell function in patients with systemic lupus erythematosus(SLE).Methods The study group included thirty-two female SLE patients who were hospitalized or received outpatient treatment in our hospital;the control group consisted of twenty-two healthy females.Their fasting plasm glucose and serum insulin were all tested.Homeostasis model assessment(HOMA) was used to calculate HOMA-IR and HOMA-?-cell function,and these parameters were compared between the study group and control group.Results Compared with control group,the SLE patients had significantly higher fasting insulin levels(12.13?4.32 vs.8.84?2.19,P0.05).Conclusion Patients with SLE have a higher risk of insulin resistance and abnormal insulin secretion than controls.
RESUMO
Objective To study the detection method of insulin resistance in congestive heart failure.Methods Levels of fasting plasma insulin and glucose were determined in 41 patients of CHF and 26 normal controls through radioimmunoassay.The application value of the inverse of the product of fasting plasma glucose and insulin (IAI) and the ratio of fasting plasma glucose and fasting insulin (FPG/FINS) were compared.Results IAI levels in patients with CHF were significantly lower than those of the control group(P