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Fundamento: Las alteraciones del estado nutricional materno generalmente se relacionan con desviaciones del crecimiento fetal, que pueden detectarse por los parámetros biofísicos fetales e identifican la posible condición trófica al nacer. Objetivo: Determinar la posible relación entre los parámetros biométricos fetales, la condición trófica al nacer y el producto de acumulación de los lípidos. Metodología: Se realizó un estudio transversal en el Policlínico Chiqui Gómez Lubian del municipio Santa Clara, durante el año 2019, en una población de 253 gestantes normopeso supuestamente sanas al inicio de la gestación. La muestra no probabilística fue de 144 gestantes. Las variables de estudio fueron: producto de acumulación de los lípidos, biometría fetal y condición trófica al nacer. Se utilizaron métodos teóricos, empíricos y estadísticos. Resultados: En el segundo trimestre ningún parámetro biométrico coincidió con la condición al nacer de pequeño, mientras que para el grande coincidieron las circunferencias cefálica y abdominal. En el tercer trimestre la longitud del fémur y la circunferencia abdominal coinciden en la identificación del pequeño y del grande. El PAL se correlacionó con la circunferencia abdominal del tercer trimestre y con el peso al nacer; presentando mayor frecuencia de valores en el tercer tertil para los nacimientos grandes. Conclusiones: La circunferencia abdominal fue el parámetro biométrico con mayor coincidencia con la condición trófica al nacer, la que se asoció con valores en el tercer tertil del PAL para la detección de nacimientos grandes, relacionándose el fenotipo normopeso metabólicamente obeso con el crecimiento fetal por exceso.
Background: Maternal nutritional status disorders are usually related to fetal growth deviations, which can be detected by fetal biophysical parameters and identify the possible trophic condition at birth. Objective: To determine the possible relationship between fetal biometric parameters, the birth trophic state and lipid accumulation product. Methodology: A cross-sectional study was conducted at the Chiqui Gómez Lubian Polyclinic in Santa Clara municipality, during 2019, in a population of 253 normal-weight pregnant women who were apparently healthy at the beginning of their gestation. The non-probability sample was made up of 144 pregnant women. Study variables were: lipid accumulation product, fetal biometry and trophic condition at birth. Theoretical, empirical and statistical methods were used. Results: In the second trimester, none of the biometric parameters matched the condition at birth as a small child, while in the large one the head and abdominal circumferences matched. In the third trimester, femoral length and abdominal circumference coincide in identifying the small one and the large one. LAP correlated with third trimester abdominal circumference and birth weight, presenting higher frequency of values in the third tertile for large births. Conclusions: Abdominal circumference was the biometric parameter with the highest coincidence with trophic condition at birth, associated with values in the third tertile of the LAP for detecting large births, relating the metabolically obese normal weight phenotype with excessive fetal growth.
Assuntos
Recém-Nascido , Biometria , Idade Gestacional , Peso Fetal , Desenvolvimento Fetal , Produto da Acumulação LipídicaRESUMO
Disinfection byproducts (DBPs) are a new class of contaminants that are formed during the process of drinking water disinfection in waterworks. To date, more than 700 DBPs have been identified in drinking water, many of which have been found to be potentially cytotoxic, genotoxic, carcinogenic, or teratogenic. As a class of ubiquitous contaminants with highly potential health hazards in drinking water, the reproductive and developmental toxicity of DBPs has been a public concern. This paper reviewed the research progress on the effects of exposure to DBPs on fetal growth and development and also proposed perspectives for future directions. This work aimed to provide reference for health risk assessment and standard establishment of DBPs in drinking water.
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Objective To discuss the determination of estriol and placenta prolactin levels for fetal grow th and development and provide theoretical basis for doctors to improve the rate of eugenic and superior nurture .Methods The pregnant women treated in the hospital from August 2014 and February 2015 were divided into two groups :pregnant women with fetal growth restriction were as the observation group(n=59) ,who with normal fetal development were as control group(n=256) .Estriol and placenta prolactin levels of two groups tested ,and the data obtained were statistically analyzed .Results Estriol level of the observation group was (13 .36 ± 2 .57)ng/mL ,which of the control group was (21 .34 ± 3 .48)ng/mL ,and the level of the observation group was lower than the control group significantly(P<0 .05) .Placenta prolactin concentration of the observation group was (3 .28 ± 0 .84)ng/mL , taht of the control group was (5 .27 ± 1 .24) ng/mL ,and the level of the observation group was lower than the control group signifi‐cantly(P<0 .05) .Estriol positive rate of observation group was 40 .68% (24/59) ,placenta prolactin positive rate was 37 .29%(22/59) ,and the positive rate of combined detection was 71 .19% (42/59) .Conclusion Examination the estriol and placenta prolac‐tin levels of pregnant female can evaluate fetal placental function .