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AIM: To analyze the effect of conbercept combined with laser photocoagulation on patients with macular edema secondary to branch retinal vein occlusion.METHODS: According to the random number table method, 102 patients(102 eyes)with macular edema secondary to branch retinal vein occlusion who treated in our hospital from January 2019 to June 2021 were divided into observation group and control group. There were 51 patients(51 eyes)in each group. The control group was treated with laser photocoagulation and the observation group was treated with conbercept combined with laser photocoagulation. The macular foveal retinal thickness, best corrected visual acuity and incidence of complications were compared among the patients of two groups.RESULTS: After treatment at 3mo, the retinal thickness of macular fovea in the observation group was lower than that in the control group(P<0.05), the best corrected visual acuity in the observation group was higher than that in the control group(P<0.05). The incidence of complications was not different between the two groups(P>0.05).CONCLUSION:The effect of conbercept combined with laser photocoagulation for macular edema secondary to branch retinal vein occlusion is remarkable to reduce the retinal thickness of macular fovea and improve the vision of patients and the complications did not increase compared with retinal laser photocoagulation therapy alone, which were safe and effective.
RESUMO
PURPOSE: To investigate the results of intravitreal injection of triamcinolone acetonide (TA) for the treatment of chronic uveitic cystoid macular edema (CME). METHODS: Six patients, 8 eyes with refractory uveitic CME were included in the study. Four milligrams of TA was injected into the vitreous cavity. The clinical outcome and complication were reviewed, retrospectively. RESULTS: Ten intravitreal injections of TA were performed, and the mean follow-up duration was 10.4 months (6~19 months). Foveal retinal thickness diminished and CME improved anatomically in 7 (88%) eyes. Visual acuity improved by 1.75 lines of the Snellen chart in 6 (75%) eyes, and the time to improvement varied from 1 week to 8 months. Inflammation decreased in all eyes and there was symptomatic improvement in 6 (75%) eyes. CME recurred in 3 (38%) eyes at 4 to 16 weeks and re-treatments were performed in 2 eyes. Intraocular pressure increased in 3 eyes and one eye needed additional filtration surgery. Cataract worsened in one eye. CONCLUSIONS: Intravitreal triamcinolone injection effectively induced anatomic and symptomatic resolution, and decreased inflammation in uveitic CME patients. Nevertheless, the visual improvement was modest, and consideration for recurrence and complication is necessary.