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Objective To explore the relationship between genital endocrine hormones and sleep disorder in climacteric depression,and study the therapeutical functions of Bushen Tiaogan Qingxin Prescription.Methods Sixty patients were randomly divided into Bushen Tiaogan Qingxin prescription group(n=30) and HRT group(n =30).The effects were appraised by both Hamilton depression rating scale(HAMD) and sleep disorder scores before and after the treatment of 12 weeks.The values of blood E2,FSH,LH were measured.Results Decreasing rate of HAMD and sleep disorder improving rate were significant in Bushen Tiaogan Qingxin prescription group than HRT group(P
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The relationship of the flow velocity of ovarian artery to the follicular growth and genital endocrine hormone was observed in 36 normal and 32 infertile women by transvaginal color Doppler imaging(TVCD). The result showed that before and after ovulation, the peak flow velocity occurred in 87 % normal women i the diestolic flow waveforms had high amplitude with low impedance, the diameters of the follicles were large, the blood E2 and LH increased and attained the peak values. However, during the time of early follicular development and late stage of luteum, the diastolic flow waveforms had low amplitude with high impedance and the blood levels of E2 and LH were low. This suggests that a close relationship exists in the flow velocity and waveform of ovarian artery to the follicular development and genital endocrine hormone. In most cases of the infertile group, the diastolic flow of ovarian arteries showed with low amplilude with high impedance > there were no mature follicle with irregular change of ovarian steriods. The study indicats that this technique may forecast the time of ovulation and investigate the causes of infertility.