Gingival metastasis from a testicular choriocarcinoma: an unusual case report and review of the literature / Metástasis gingival desde un coriocarcinoma testicular: un inusual reporte de caso y revisión de la literatura

Metastasic tumours to the oral cavity are extremely rare lesions that represent 1% of all oral and maxillofacial malignancies. Most reported cases involve the jaw bones than the soft tissues. Metastasis to the oral soft tissues most prevalently affects the gingiva and alveolar mucosa. Gingival metastasis may have an unremarkable clinical appearance and they can be difficult to distinguish from more common hyperplasic or reactive lesions that appear to be benign entities, such as peripheral giant-cell granuloma, pyogenic granuloma and peripheral ossifying fibroma. We present an unusual case of a testicular choriocarcinoma metastasized to the maxillary gingiva mimicking a reactive lesion. In addition, we also present a literature review of previous reported cases and a brief discussion about the etiopathogeny of testicular germ cell tumors, and how these malignant cells can reach the gingival tissues.

Los tumores metastásicos a la cavidad bucal son lesiones extremadamente raras que representan el 1% de todas las neoplasias malignas bucales y maxilofaciales. La mayoría de los casos reportados afectan más a los huesos maxilares que los tejidos blandos. Las metástasis a los tejidos blandos bucales involucran más prevalentemente a la encía y la mucosa alveolar. Las metástasis gingivales pueden tener un aspecto clínico no característico y suelen ser difíciles de distinguir de otras lesiones hiperplásicas o reactivas que parecen ser entidades benignas, tales como el granuloma periférico de células gigantes, el granuloma piogénico y el fibroma osificante periférico. Presentamos un inusual reporte de caso de un coriocarcinoma testicular metastásico a la encía maxilar simulando una lesión reactiva. Además, también se presenta una revisión de la literatura de los casos previamente publicados y una breve discusión acerca de la etiopatogenia de los tumores testiculares de células germinales, y cómo estas células malignas pueden llegar a los tejidos gingivales.

A case of lung cancer with gingival metastasis successfully treated by palliative care

We report a patient with gingival metastasis of lung cancer in whom the use of sedatives was successfully avoided by employing holistic care approaches. A 64-year-old man had been receiving chemotherapy with the diagnosis of advanced lung cancer. Eighteen months later, a rapidly growing gingival metastasis was observed. Arterial embolization was performed, but it failed to control the bleeding. No active treatment was performed, and he was subsequently transferred to our hospital. He desired death, with markedly pessimistic views, and wished to undergo deep and continuous palliative sedation (DCPS) due to severe total pain (particularly psychological and spiritual) from the beginning. However, he died peacefully before receiving DCPS. We present a literature review of gingival metastasis from lung cancer, as well as our assessment and palliative care for the total pain of this patient.

A Case of Hepatocellular Carcinoma with Metastasis to Gingival Mucosa / 대한간학회지

Hepatocellular carcinoma is one of the most common causes of death in Koreans. Most cases of hepatocellular carcinoma are beyond the stage of curative resection at the time of diagnosis due to extrahepatic metastasis as well as wide distribution of tumor in the liver. The lung is the most common site of extrahepatic metastasis but metastasis to gingiva is very rare in hepatocellular carcinoma. We report a case hepatecellular carcinoma with gingival methststasis in a 59 year old male patient.

A Case of Small Cell Lung Cancer Metastasis to the Gingiva / 결핵

The incidence of lung cancer and its mortality rate are increasing in Korea. At the time of diagnosis, 40% patients of lung cancer patients had metastatic lesions. The common metastatic sites are the contralateral lung, bone, liver, adrenal gland and the brain. Metastasis to oral mucosa is rarely encountered in lung cancer and metastasis to the gingiva is more uncommon. Approximately 1% of malignant carcinomas in the oral cavity are the result of metastases, and 10-25% of metastatic cancers originate from lung cancer. Clinically metastatic gingival lesions are benign including hemangioma, pyogenic granuloma, giant-cell granuloma or a peripheral fibroma. Often metastases to the gingiva are diagnosed too late and by the time they are detected, they have metastases to other organs. Here we report a case of small cell lung carcinoma that had metastased to the gingiva with review of relevant literature.