Observation on expiration date and disinfectant efficacy of an alcohol-based hand disinfectant / 中国感染控制杂志

Objective To understand the expiration date of alcohol-based hand disinfectant after it is opened for use,and provide reference for rational clinical application of alcohol-based hand disinfectant.Methods 20 bottles of the same brand alcohol-based hand disinfectant which opened at the same time by the clinical departments were selected as the study object,hand hygiene compliance in theses departments ranked fourth from the end in the hospital,specimens were taken on the first day after opening,and repeated every 10 days until the disinfectant was used up.Hand specimens were also taken after disinfected by disinfectant.Qualified condition of disinfectant and hand specimens was detected.Results A total of 98 disinfectant specimens were collected,by naked eye observation,20 bottles of alcohol-based hand disinfectant were free of discoloration,precipitation,and suspended matter during the whole study period.The qualified detection rates of alcohol-based hand disinfectant within 60 days after opening were all 100%.44 hand specimens were taken and detected after disinfection,3 of which were unqualified(all were disinfected by alcohol-based hand disinfectant 50 days after opening),then detected again after disinfected by the same batch of disinfectant,all were qualified,which suggested that unqualified detection result of hand specimens was not due to disinfectant.Conclusion Alcohol-based hand disinfectant still has a good bactericidal effect on the sixth day after opening.

Validation of method for microbial limit test of fast vertical liquid hand disinfect-ant gel / 药学实践杂志

Objective To establish a method for microbial limit test of fast vertical liquid hand disinfectant gel .Methods The membrane filtration method, in accordance with the Chinese Pharmacopoeia 2010 Edition (part two) relevant requirements of microbial limit test method for validation of microbial limit test for fast vertical liquid hand disinfectant gel .Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Candida a lbicans, Aspergillus niger were taken as test bacteria , Pseudomonas aeruginosa and Staphylococcus aureus were taken as control bacteria .Verification test was carried out in parallel test for 3 independent , recoveries and every trail rate were calculat-ed.Results In bacteria, molds and yeasts count method validation test , recovery test strain rate , the control bacteria test results met the requirements.Conclusion The membrane filtration method was feasible and effective , which could be used for microbial limit test of fast vertical liquid hand disinfectant gel .

Influence of the placement of instant hand disinfectant in hand hygiene compliance of clinicians / 中国感染控制杂志

Objective To evaluate the influence of the placement of instant hand disinfectant in compliance and qualified rate of hand hygiene of clinicians.Methods Hand hygiene compliance of clinicians in departments of gyne-cology,obstetrics,and general surgery were observed after the placement of instant hand disinfectant at the door-way of wards,hand specimens were taken to check hand hygiene effectiveness.Results Before and after placement of instant hand disinfectant at the doorway of wards of above departments,hand hygiene behaviors of 300 person-times were observed.Hand hygiene compliance rate among clinicians in department of gynecology,obstetrics,and general surgery increased from 32.33% to 74.33%,33.67% to 85.67%,and 26.33% to 64.00%,respectively(all P <0.001).Each department selected 98 hand hygiene specimens,the qualified rate was 98.98%,100.00% and 94.90% respectively.Conclusion The placement of instant hand disinfectant at the doorway of each ward can effec-tively improve clinicians’hand hygiene compliance and hand hygiene effectiveness.