Progress in research of immunoassay based on SERS labeling technique / 军事医学

A new medical research technology that combines surface enhanced Raman spectroscopy (SERS)with labeling immune technique is emerging with the development of SERS.This paper is intended to describe the principles, research progress and existing problems relating to SERS labeling immunoassay technology.We also summarize the research techniques for improving the sensitivity of SERS labeling immunoassay and the methods to eliminate nonspecific adsorption in SERS labeling immunoassay.Furthermore,the future development of SERS labeling immunoassay technology is discussed.