Diagnosis and Treatment Reasoning of Integrated Traditional Chinese and Western Medicine Against Acute Abdomen Based on Knowledge Graph / 中国实验方剂学杂志

ObjectiveIn view of the standardization of clinical diagnosis and treatment of the acute abdomen and the inheritance of diagnosis and treatment experience of prestigious veteran traditional Chinese medicine（TCM） doctors， a diagnosis and treatment reasoning algorithm based on association rule mining under incomplete evidence（AMIE）+ random walk was proposed to provide information services and technical support for primary doctors by recommending personalized diagnosis and treatment plans based on medical records. MethodThe experience of diagnosis and treatment of acute abdomen of prestigious veteran TCM doctors and the text data of clinical diagnosis and treatment guidelines of integrated TCM and western medicine were collected to complete the task of knowledge extraction and construct acute abdomen knowledge graph based on Neo4j. On the basis of ontology-supported rule-based reasoning， the rule reasoning based on similar syndromes was used to expand the syndrome combinations whose Jaccard similarity was greater than the threshold in the syndrome recommendation results. The semantic path coverage algorithm was used to calculate the semantic similarity between the symptom nodes. The symptom nodes were divided into 10 categories， and the symptom nodes in the same category were extended. The random walk algorithm was used to search the symptom nodes connected with the syndrome， and the connection rules between the syndrome and symptom nodes were extended to realize the knowledge reasoning of AMIE+ random walk. ResultThe acute abdomen knowledge graph included 1 320 nodes and 2 464 relationships. According to the link prediction evaluation index of knowledge reasoning， the reasoning results of the three algorithms in the auxiliary diagnosis and treatment of acute abdomen were compared. The AMIE+ random walk algorithm complemented the knowledge graph by extending the similar syndrome connection rules and the syndrome-symptom connection rules. Compared with the knowledge reasoning algorithm based on ontology rules， the area under the curve （AUC） was 15.18% higher and the accuracy was 30.36% higher， which achieved more accurate and effective knowledge inference. ConclusionThis study used knowledge graph technology to visualize the diagnosis and treatment of acute abdomen with TCM and western medicine， assisting primary clinicians in intuitively viewing the diagnosis and treatment process and data relationship. The proposed diagnosis and treatment reasoning algorithm can realize the personalized diagnosis and treatment plan recommendation at the level of "disease-syndrome-diagnosis-treatment-prescription"， which can assist primary doctors in disease diagnosis and treatment and clinical decision-making， contribute to the knowledge sharing and application of diagnosis and treatment experience and clinical guidelines of prestigious veteran TCM doctors， improve the level of primary clinical diagnosis and treatment， and promote the normalization and standardization of the diagnosis and treatment process of acute abdomen with integrated TCM and western medicine.

Professor Gao Li's thoughts on diagnosis and treatment of cerebral infarction by integration of traditional Chinese and western medicine / 中国中西医结合急救杂志

Presently the four high characteristics and rejuvenation trends of cerebrovascular diseases are still the main problems that endanger the health of our people. Accordingly, Professor Gao Li has been committed to the discussion of risk factors for cerebrovascular diseases and the practice of using integration of traditional Chinese and western medicine for diagnosis and treatment of these diseases. In order to enable the majority of western medicine doctors to understand and accept his idea, Professor Gao Li combines traditional Chinese medicine (TCM) syndromes with modern etiology and pathology, classification of stages and types of cerebral infarction by Chinese and western medicine, the acute cerebral infarction patients are simplified innovatively into four TCM syndromes and appropriate treatments are given to them, so that the majority of traditional Chinese and western medicine doctors can comprehensively recognize the condition of this disease from macroscopic to microscopic points of view. By his above combination of traditional Chinese and western medicine reasoning, the patients obtained better curative effect. After multiple years of summary and accumulation of his experiences, Professor Gao Li has developed the distinct clinical and academic characteristics for the diagnosis and treatment of cerebral infarction.

Integrated traditional Chinese and Western medicine for the treatment of ulcerative colitis: Advantages and clinical application / 医学研究生学报

Ulcerative colitis is a chronic nonspecific inflammatory disease of unknown etiology and, with a rising incidence and prevalence in recent years, has become a focus as well as a difficulty in clinical treatment. With the increase of severe and difficult cases and change of therapeutic objectives, neither Western nor traditional Chinese medicine alone can meet the clinical needs, while integrated traditional Chinese and Western medicine has manifested its advantages of promoting deep remission, improving patients' quality of life and saving medical resources. How to give full play to the characteristic advantages of integrated traditional Chinese and Western medicine and choose the best combination paradigm and timing remains to be further explored.

Discussion on Treatment of Anti-cancer Medicine Based on Principles of Cold and Heat Syndrome Differentiation / 医药导报

Due to the differences of background, ways of thinking, visual angle and research tools between Chinese medicine and Western medicine,most Chinese medicine research based on western medicine are of low clinical value,although the combination of the Western and Traditional Chinese Medicine has gaining popularity.It is possible to change our perspective and use Chinese medicine theory to think and guide all modern treatment methods.This theory which is explained in the Tumor Green Therapeutics,has achieved remarkable clinical results and gained rapid development.Syndrome differentiation and treatment is the essence of TCM.Eight principles of syndrome differentiation of TCM are the general principles. The principles of cold and heat syndrome differentiation are the basis for the complex syndrome types.Therefore, this article will be a preliminary study for anti-cancer medicine from point of view of the principles of cold and heat syndrome differentiation, and will provide more clinical reference.

Nursing of Integration of Traditional Chinese and Western Medicine for Acute Myocardium Infarction: 30 Cases Report / 中国康复理论与实践

@#Objective To observe the prognosis of acute myocardium infarction (AMI) patient accepted nursing of Integration of Traditional Chinese and Western Medicine. Methods 30 hospitalized AMI patients were reviewed. Results All the patients finished the rehabilitation program successfully and achieved satisfied outcome, except a patient dropped for severe respiratory failure after respiratory diseases. Conclusion Nursing of Integration of Traditional Chinese and Western Medicine is effective on acute myocardial infarction patients.

Observation on the treatment diabetic peripheral neuropathy with methylcobalamin and Chinese medicines of nourishing Yin and promoting blood circulation / 国际中医中药杂志

Objective To observe the effect of treating diabetic peripheral neuropathy(DPN) with methylcobalamin and Chinese medicines with the funetious of nourishing Yin and promoting blood circulation. Methods 72 patients with DPN were randomly recruited into a control group and a treatment group.Symptoms, NCV,value of blood routine examination,blood biochemistry check and ECG were compared before and after the treatment. Results The total effective rate was 88.0% and 68.2% in the treatment group and the control group respectively,showing significant difference (t=3.14, P<0.01).The value of blood routine examination, blood biochemistry check (except blood sugar level) and ECG showed no obvious changes before and after the treatment in both groups.Conclusion Therapy of methylcobalamin Tablets with Chinese medicines of nourishing Yin and promoting blood circulation is effective on DPN and worth of clinical promotion.