Progress in Gene Therapy of Hereditary Neurological Ion Channel Disease / 中国综合临床

Current therapies for hereditary neuropathy are often difficult to control or have low patient tolerance,so it is imperative to explore new therapies??Gene therapy has been shown that in many studies it may be applied to nervous system diseases and may become an effective treatment for hereditary nervous system ion channel diseases in the future??At the same time,the continuous progress of photogenetics, chemical genetics and gene editing technology also provides a good basis for the development of gene therapy for hereditary neuropathy??We will review the methods, mechanisms, transduction vectors, promoters and administration routes of gene therapy for hereditary neurological ion channel disease??

Advance in study of cardiovascular ion channel diseases / 中国临床药理学与治疗学

The cardiovascular ion channel disease is one of the main among ion channel diseases.It plays the important effect of cardiovascular disease.Ion channel diseases are responsible for almost all arrhythmias and sudden cardiac death.This text reviews genetic and acquired cardiac ion channel diseases,and associated treatments are introduced briefly.