Application of LBW index combined with energy spectrum CT in reducing the contrast agent dose of liver enhanced CT / 西安交通大学学报(医学版)

【Objective】 To compare the enhancement effects of lean body weight （LBW） and total body weight （TBW） as indexes to calculate the contrast agent dosage under the condition of energy spectrum CT scanning. 【Methods】 A total of 218 patients who received liver enhancement CT from November 2018 to January 2019 were enrolled in this study. There were 101 patients in LBW group and 117 patients in TBW group. Both groups were scanned by energy spectrum CT， and the parameters of scanning and reconstruction were identical. The contrast agent dose was 500 mgI/kg （LBW） in LBW group and 450 mgI/kg （TBW） in TBW group， and the injection rate was 2.8 mL/s. Images were transferred to a GE AW4.7 workstation and the 50 keV monochromatic images were analyzed. We compared the dosage of contrast medium， CT value of aorta in arterial phase （HU-aorta）， hepatic enhancement CT value in venous phase （-liver）， the rate of reaching the enhancement standard and variability in the two groups. 【Results】 Compared with TBW group， LBW group had lower contrast agent dosage， HU-aorta and ∆-liver （P0.05）. The variation rate of HU-aorta and ∆-liver in LBW group was lower than that in TBW group. Using LBW as an index to calculate the dosage of liver enhanced CT also made the enhancement of liver parenchyma more consistent in different patients. 【Conclusion】 Even on the premise of energy spectrum CT scanning， using LBW-based contrast injection in liver enhanced CT can not only reduce contrast dose， but also make the enhancement in liver parenchyma more consistent among different patients.

Comparative study among total body weight,lean body weight and body surface area adj usted iodine contrast agent dose protocols on liver enhanced CT scans / 实用放射学杂志

Objective To explore the optimal body size index for the calculation of iodine contrast agent dose required for multiphase liver enhanced CT scans based on the total body weight (TBW),lean body weight (LBW)and body surface area (BSA).Methods Two hundred and twenty enrolled patients were randomly divided into three groups,TBW-group (n＝75),LBW-group (n＝72)and BSA-group (n＝73),and administrated iodine doses were 600 mg I/TBW(kg),780 mg I/LBW(kg)and 22 g I/BSA(m2 ),respectively.All patients had taken upper abdominal plain scans and triple-phase enhanced CT scans.The enhanced values (ΔHU)of the aorta at hepatic arterial phase (HAP),the portal vein and liver parenchyma at portal venous phase (PVP)were compared.The correlation coefficients of adjusted maximal hepatic enhancement(aMHE)with TBW,LBW and BSA in three groups were evaluated,respectively.Results There were no statistical differences in the ΔHU values of the aorta at HAP and the portal vein and liver parenchyma at PVP in the three groups respectively.The smallest variances of the aorta at HAP,the portal vein and liver parenchyma at PVP were found in the LBW group. The aMHE showed mildly positive correlation with TBW (r＝0.230)with a P value of 0.047,but it was consistent with LBW (r＝0.158)and BSA (r＝－0.1 54)with corresponding P values of 0.1 85 and 0.1 9 2 ,respectively.Conclusion Compared with TBW and BSA,iodine contrast agent dose calculated based on the patient’s LBW can improve the patient-to-patient uniformities on aorta,portal vein and liver enhancement during the liver multiphase enhanced CT scans.The LBW is the best body index for the calculation of iodine dose on liver enhanced CT scans.

Effects of different doses of propofol on cardiac pump function in morbidly obese patients / 实用医学杂志

Objective To compare the effects of different doses of propofol on cardiac pump function in morbidly obese patients. Methods Forty morbidly obese patients undergoing laparoscopic Roux-en-Y gastric by-pass were randomly divided into lean body weight(LBW)group and total body weight(TBW)group,with 20 cases in each group.In LBW group,patients were induced by propofol with a dose according to LBW(kg)×2.0 mg/kg but in TBW group,patients were induced by propofol depending on TBW of the patients.We monitored the changes of left ventricular ejection fraction(LVEF)and stroke volume(SV)in patients before anesthetic induction(T1)and at 1 min(T2)after propofol administration.At the same time,we monitored invasive arterial pressure,noninvasive arterial pressure,BIS,and SpO2.Results Compared with those measured at T1,LVEF and SV were decreased af-ter the induction of anesthesia in the 2 groups(P < 0.05);compared with LBW,TBW had greater influence on LVEF and SV after the induction of anesthesia(P<0.05);compared with those at T1,non invasive arterial blood pressure,invasive arterial blood pressure and mean arterial pressure decreased after theinduction of anesthesia (P<0.05);compared with LBW,TBW had no significant effect on noninvasive arterial blood pressure,invasive arterial blood pressure and mean arterial pressure after the induction of anesthesia(P < 0.05);BIS was less than 50 after the induction of anesthesia in 2 groups. Conclusion Propofol induction with a LBW-dependent dose has less influence on cardiac pump function in morbidly obese patients while ensuring the depth of anesthesia.

The clinical application of creatinine clearance predicted from lean body weight / 中国实用内科杂志

Objective\ To evaluate the possibility of predicting renal function from creatinine clearance calculated by lean body weight(LBWCcr).Methods\ 81 patients of renal disease were selected.The ratio between 24-hour urinary creatinine excretion(24hUcr)and lean body weight(LBW)was evaluated in 51 patients.The other 30 patients was determined DTPA-GFR,LBWCcr and 4hCcr.DTPA-GFR was used as criteria.LBWCcr and 4hCcr were compared with it in order to validate the feasibility of LBWCcr and 4hCcr.Results\ There was no statistical significance among the three methods,P=0 56 The correlation coefficient between LBWCcr and 4hCcr with DTPA-GFR was 0 89 and 0 86,respectively.The analysis of linearity regression showed that the trend of LBWCcr was better than 4hCcrmin in predicting renal function.In fatty group and renal failure group the results were similar.Conclusion\ LBWCcr can estimate the renal function accurately,simply and rapidly.

Effect of the bone mineral content variation on the body fat ratio computation in young adults / 体力科学

Bone mineral content (BMC), fat weight (FAT) and lean tissue weight (LTW) were determined by dual-energy X-ray absorptiometry (DEXA) in 20 young adults of both sexes who were performing habitual exercise. From these data, body weight, lean body weight (LBW) and the percentage of BMC relative to LBW (BMC%LBW) were obtained. First, body density based on a two-component model (D<SUB>2</SUB>) was calculated using the values of FAT and LBW of the subjects and the fat and lean densities of the Reference Body, Then percentage body fat (%Fat<SUB>2</SUB>) was calculated using the formula of Brozek et al. The body density for a three-component model (D<SUB>3</SUB>) was then determined from the values of FAT, BMC and LTW of the subjects, and the fat, bone mineral and lean tissue densities of the Reference Body. Percentage body fat (%Fat<SUB>3</SUB>) was also calculated in the same manner as %Fat<SUB>2</SUB>. Analysis of the data indicated that (1) females had higher values of BMC%LBW than males, and that (2) subjects whose %Fat<SUB>2</SUB> exceeded %Fat<SUB>3</SUB> by more than 1% were exclusively females whose BMC%LBW values were more than 6.1%. In contrast, those whose %Fat<SUB>2</SUB> was lower than %Fat<SUB>3</SUB> by less than -1% were exclusively males who had BMC%LBW values less than 5.2%. It is concluded that male subjects develop their muscles more than their bones with habitual exercise, which results in a lower BMC%LBW value than in females, and that for those with BMC%LBW values exceeding 6.1% (females) or less than 5.2% (males), %Fat calculation from body density using the formula of Brozek et a1. will produce an error of more than 1% if BMC%LBW is not considered.

The Investigation of Body Composition of Chinese Athletic Bodybuilders / 中国运动医学杂志

0.05),but lean body weight(LBW) and total body water(TBW) increased significantly(P0.05),whereas LBW and TBW decreased significantly(P0.05),whereas LBW and TBW increased significantly(P

CORRELATION OF BIOELECTRICAL IMPEDANCE WITH BODY FAT OR LEAN BODY WEIGHT OF CHILDREN / 营养学报

Twenty-two normal children were studied for body fat (BF) and lean body weight (LBW) by a hydrodensitometric technique, whole-body bioelec-trical impedance values (Z) using a 177 kHz, 100?A signal and various an-thropometric data. Two bioelectrical impedance indices (BII) were ZW/H2 and H2/Z. The linear correlation coefficients between ZW/H2 and BF and between H2/Z and LEW were 0.9617 and 0.9326 (P