RESUMO
Objective To explore and analyze clinical efficacy and safety of restructuring morphogenesis protein-2 bones(rhBMP-2) combined with nanocrystalline collagen bone material(nHAC) fusion between treating lumbar protrusion of the lumbar spine instability.Methods Ninety cases of patients with lumbar instability syndrome who were treated in the People's Hospital of Heze from March 2013 to May 2013were selected and divided into restructure morphogenesis protein-2 combined with nanocrvstalline bone collagen bone material treatment group,purely in nanocrystalline collagen bone material treatment of the control group according to the random number table method,45 cases in each group.JOA evaluation results,intraoperative blood loss,postoperative infection,pulmonary complications within three months of the two groups were compared.Results The male proportion of experimental group and control group was 46.67％ and 48.89％respectively,the difference was significant(x2 =0.03,P =0.84).The excellent rate ofexperimental group and control group was respectively 93.33％,57.78％,the difference was significant (x2 =5.49,P ＜ 0.05).The incidence of deep vein thrombosis,infection rate,incidence of pulmonary complications of experimental group were 4.44％,8.88％,6.67％,of control group were 13.33％,24.44％,20.00％,the differences were significant (x2=5.12,3.78,3.56;P＜0.05).Conclusion Restructuring morphogenesis protein-2 bones combined with nanocrystalline collagen bone material treating lumbar fusion between the clinical curative effect of treating lumbar instability syndrome is better,with a lower incidence of complications,security is relatively high,compared to traditional surgery method has many advantages,can be used as a kind of ideal method used in the clinical work.
RESUMO
Objective To observe the clinic efficacy of open transforaminal lumbar interbody fusion (TLIF) compared with minimally invasive operation in treating lumbar spinal stenosis and instability among obese and non‐obese patients .Methods A ret‐rospective analysis was performed in these cases of mono‐segmental lumbar spinal stenosis and instability between January 2011 and January 2013 .Perioperative index ,clinical efficacy ,and imaging results were observed and compared between different groups .Re‐sults Thirty‐four obese cases and 105 non‐obese cases were divided into two groups ,including conventional posterior open TLIF and minimally invasive TLIF operation ,to compare the results .Perioperative indexes of obese patients were more than non‐obese patients undergone open TLIF operation way and there was significant difference(P0 .05) .No cases of slippage or breakage of implants were found among all these patients after 6 months of follow up .Postoperative VAS and ODI among these four groups were better than before(P0 .05);undergoing minimally invasive postoperative VAS in obese group and in non‐obese group ,there was not significant difference(P>0 .05) .Conclusion Therefore ,obese may be risk factor in treating lumbar spinal stenosis and instability .