Organic acids from leaves of Cerbera manghas / 中草药

Objective: To study the organic acids in the leaves of Cerbera manghas. Methods: The constituents were isolated by repeated column chromatography and their structures were elucidated on basis of physico-chemical constants and spectral data analyses. Results: Seven compounds were obtained and determined to be m-carboxyphenylacetic acid (1), p-hydroxybenzoic acid (2), protocatechuic acid (3), p-hydroxycin-namic acid (4), isophthalic acid (5), vanillic acid (6), and succinic acid (7). Conclusion: Compound 1 is a new natural product, compounds 2-6 are obtained from the plants of Cerbera L. for the first time.