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@#AIM: To discuss the clinical effects of pars plana vitrectomy(PPV)combined with interal limiting membrane peeling(ILMP)for macular hole(MH)in pathological myopic eyes.<p>METHODS: This is a retrospective case study. Eighteen patients(19 eyes)with high myopic MH diagnosed in our hospital from January 2017 to January 2019 were enrolled in this study. All eyes were grouped for pathological myopia(9 patients 10 eyes)and non-pathological myopia groups(9 patients 9 eyes). All eyes were treated with PPV combined with ILMP surgery. Postoperative follow up was 3-23mo, the efficacy was determined at the final follow up, including BCVA, visual deformation symptoms and macular hole closure.<p>RESULTS: During the final follow up, BCVA was improved in 6 eyes,stable in 2 eyes, more severe in 2 eyes in pathological myopia group, and MH was fully closed in 7 eyes(70%), bareness-closed in 2 eyes(20%)and not closed in 1 eye(10%). In non-pathological myopia group, BCVA was improved in 6 eyes,stable in 2 eyes, more severe in 1 eyes, and MH was fully closed in 8 eyes(88%), not closed in 1 eye(11%). There were significant differences in the axial length between the two groups before surgery, axial length was negatively correlated with the macular hole closure rate at the last follow up(<i>rs</i>= -0.477, <i>P</i>=0.039).<p>CONCLUSION: PPV combined with ILMP for the treatment of MH in high myopia can effectively improve BCVA. However, the hiatal closure rate of pathological myopia patients was lower than that of non-pathological myopia patients.
RESUMO
@#AIM:To investigate the effect of internal limiting membrane(ILM)transplantation in the treatment of large macular hole.<p>METHODS: Totally 35 patients with large macular hole(>700μm)underwent vitrectomy in our hospital from March 2016 to March 2018 were retrospectively analyzed, in which group A(17 patients)underwent vitrectomy and internal limiting membrane peeling generally, group B(18 patients)underwent vitrectomy and internal limiting membrane transplantation. The best corrected visual acuity(BCVA)and macular hole closure rate were performed preoperative and 3mo postoperative. <p>RESULTS: The macular hole closure rate in group A was 65% at 3mo safter surgery, and macular hole closure rate in group B was 100% at 3mo after surgery(<i>P</i><0.05). The rate of BCVA of A group which were significantly improved at 3mo postoperative(increase by 2 lines or more)compared preoperative is 35%, and the rate of BCVA of B group is 78%(<i>P</i><0.05).<p>CONCLUSION: Internal limiting membrane transplantation can improve the closure rate of large macular hole and visual function after surgery in a certain extent. It is a safe and effective surgical method.