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@#AIM: To analyze the correlation between subjective mean sensitivity and visual function <i>via</i> macular microperimetry.<p>METHODS: Totally 164 eyes of 127 patients with macular edema were involved in this study. According to different diseases, they were divided into 3 groups: age-related macular degeneration(AMD)(38 eyes), retinal vein occlusion(RVO)(43 eyes)and diabetic macular edema(83 eyes)groops. All patients underwent the examinations of optometry, optical coherence tomography scanner(OCT)and microperimeter. Correlation analysis was performed using Pearson, and <i>t</i>-test among groups.<p>RESULTS: Mean sensitivity(MS)values and fixation rate(P1, P2)of total patients with macular edema were significantly correlated with their BCVA, meanwhile the CRT was negatively correlated. MS values were significantly correlated with BCVA in AMD group, but the P1, P2 and CRT were not correlated. In DME and CRVO groups, MS values and P1, P2 were significantly correlated with BCVA, and CRTs were negatively correlated in DME but not correlated in CRVO. In BRVO group, MS values and CRTs were all not correlated with BCVA.<p>CONCLUSION:Microperimetry is probably a better subjective assessment for AMD macular function than OCT, and could be combined with OCT for function follow-up in DME and CRVO patients. For BRVO microperimetry might indicate certain macular dysfunction that could not be detected by VA or CCT. Microperimetry could be a subjective examination for the assessment of macular edema combined with OCT.
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@#AIM: To investigate the condition of visual acuity and macular edema after cataract surgery in diabetes mellitus(DM)patients with fundus lesions. <p>METHODS: Totally 97 eyes of 97 patients with cataract and DM fundus lesion treated in our hospital from January 2016 to September 2017 were selected, and were divided into the observation group A, 43 cases 43 eyes(DM duration <5a), observation group B, 54 cases 54 eyes(DM duration ≥5a). Besides, 60 eyes of 60 patients with simple cataract were selected as the control group. The best corrected visual acuity(BCVA)and macular retinal thickness(foveal area, inner ring area, outer ring area), and the retinal mean sensitivity(MS)were observed before and after the treatment. <p>RESULTS: BCVA in control group and observation Group A was better than that in observation Group B(0.24±0.09)at 1mo after operation, and the difference was statistically significant(<i>P</i><0.05). The thickness of fovea, inner ring and outer ring in Group B were 283.30±17.06μm, 335.51±20.26μm and 297.28±20.22μm, which were significantly higher than those in Group A and control group, and the difference was statistically significant(<i>P</i><0.05). The MS in Group B(11.54±1.89dB)were obviously lower than the observation Group A and the control group, the difference was statistically significant(<i>P</i><0.05). After 3mo, the total leakage rate of Group B(55.6%)was significantly higher than that of Group A and control group(<i>P</i><0.0167). <p>CONCLUSION: Compared with simple cataract patients, the retinal thickness of patients with DM fundus disease is significantly increased, which is easy to has macular edema, and affects postoperative visual acuity recovery, in the patients with longer DM course which are especially obvious.