RESUMO
Introducción: La retinopatía asociada a melanoma (RAM) es un desafío para el equipo tratante de pacientes oncológicos debido a la inespecificidad del cuadro clínico y a la dificultad de realizar exámenes que ofrezcan un diagnóstico. Métodos: Paciente 55 años, sexo femenino con diagnóstico de melanoma, consulta por escotoma central asociado a síntomas visuales positivos. Resultados: Examen oftalmológico dentro de rangos normales. Electrorretinograma (ERG) estándar muestra respuesta máxima electronegativa en ambos ojos, sugerente de RAM. Discusión: El reconocimiento temprano de RAM mediante ERG tiene importancia diagnóstica, permitiendo iniciar tratamiento temprano y reducir el riesgo irreversible de daño a la retina.
Introduction: Melanoma-associated retinopathy (MAR) is a challenge for the oncology team due to the non-specific clinical presentation and the associated difficulty of performing indicative tests for diagnosis. Methods: A 55-year-old female patient initially diagnosed with melanoma consults due to vision with central scotoma associated with positive visual symptoms. Results: Ophthalmological examination within normal ranges. Standard electroretinogram (ERG) shows the maximum electronegative response in both eyes, suggesting MAR. Discussion: The early recognition of MAR by ERG has diagnostic importance because it would allow a possible early treatment and could reduce the risk of irreversible retina damage.
RESUMO
The aim was to report the first case of cancer‑associated retinopathy (CAR) presenting before bladder cancer diagnosis. A 71‑year‑old woman with a history of bilateral vision loss underwent subsequent complete ophthalmic examination include a fluorescein angiography, full‑field electroretinogram (ERG), serology including serum antibodies for CAR, and positron emission tomography‑computed tomography (PET‑CT) scan. The patient was diagnosed with Cite this article as: Nivean M, Muttuvelu DV, Afzelius P, Berman DC. Paraneoplastic retinopathy associated with occult bladder cancer. Indian J Ophthalmol 2016;64:248-50. This is an open access article distributed under the terms of the Creative Commons Attribution‑NonCommercial‑ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non‑commercially, as long as the author is credited and the new creations are licensed under the identical terms. For reprints contact: reprints@medknow.com bladder carcinoma revealed by PET‑CT. Timely recognition of this entity may be crucial for an increased patient survival thus adult onset progressive photoreceptor dysfunction, confirmed by ERG, should alert to a possible remote effect of known or occult malignancy. In the latter, PET‑CT may be exploited as a powerful diagnostic tool.