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Objective To discuss the value of contrast-enhanced ultrasound(CEUS)parameters in evaluating the formation of Kimmelstiel-Wilson(K-W)nodules in diabetic nephropathy(DN).Methods Sixty-two patients pathologically diagnosed with DN and undergoing CEUS in the First Medical Center of Chinese PLA General Hospital from March 2017 to January 2020 were assigned into two groups according to whether K-W nodules were formed.The cortical CEUS parameters and the ratios of cortical to medullary CEUS parameters were compared between the two groups.Results The 62 patients included 19 patients without K-W nodules(group A)and 43 patients with K-W nodules(group B).The median rise time(
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Humanos , Meios de Contraste , Diabetes Mellitus , Nefropatias Diabéticas/diagnóstico por imagem , UltrassonografiaRESUMO
Objective To evaluate the application value of quantitative parameters of contrast-enhanced ultrasound (CEUS) in evaluating the donor liver from donation after brain death (DBD). Methods Clinical data of 25 DBD donor livers and 10 healthy adult livers were retrospectively analyzed. CEUS examinations of DBD donor livers and healthy livers were collected. Quantitative parameters included the area under curve (AUC), maximum intensity (Imax), time to peak (TTP) and mean transit time (mTT), etc. Results Among 25 cases of DBD donor livers, 23 cases showed normal enhancement pattern, and the other 2 cases presented with abnormal enhancement pattern. Compared with the control group, the AUC, Imax and mTT values of DBD donor livers were significantly decreased (all P < 0.05). Conclusions CEUS quantitative parameters can be effective means to evaluate the micro-perfusion of DBD donor livers.
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Objective To make a concrete analysis of micro-perfusion pump and compatible syringes used in neonatal intensive care unit (NICU) for low birth weight infants,and to find solutions to the defects in application.Methods 20 ml sterile syringes were set different infusion rates (1ml/h,5ml/h,6ml/h,10ml/h),different infusion time (5min,30min,lh).Then,the card slot on the micro-perfusion pump where the end of 20ml sterile syringe was placed was regulated.The regulated syringes were also set different infusion rates (5ml/h,6ml/h,l0ml/h) and time as before.The error accuracy was calculated.Results The results showed that at the end stage of 20ml sterile syringes pumping,there was always 0.5～1.5 ml residual liquid which could not be pumped out,but perfusion pump displayed injection was completed.Before regulation,the error accuracy between different infusion rates of 20ml sterile syringes was 6.00％,3.80％,2.33％,1.30％ respectively.However,after improvement,the regulated syringes could completely pump all liquid out,and the error accuracy between different infusion rates and different infusion time was also superior to pre-improvement.Conclusions Improved micro-infusion pump and sterile solution prefilled syringe have no drug residual,and display high accuracy and small error accuracy.
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@#ObjectiveTo evaluate the feasibility and the value of videodensitometric scale (VDS) in assessing myocardial microperfusion. Methods11 Beagles were embolized small coronary artery with polystyrene microbubble (100 μm). Coronary angiography was performed after the embolization and the VDS was calculated. Single photon emission computerized tomography (SPECT) was also performed after embolization and SPECT scores were also calculated. ResultsVDS after embolization was (15.2±3.8); and SPECT score was (17.6±6.4). VDS correlated negatively with SPECT scores (r=－0.85, P<0.05).ConclusionVDS keeps a closely correlation with SPECT. It can be used to assess myocardial microcirculation in clinical.
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@#Objective To evaluate the feasibility and the value of videodensitometric scale(VDS)assessing myocardial microperfusion.Methods The small coronary arteries of 11 dogs were embolized by ejecting polystyrene microbubble(dm= 100 μm),six embolized at left anterior descending branch(LAD)and five embolized at left circumflex branch(LCX).Coronary angiography was performed before and after the embolization.The myocardial contrast echocardiography(MCE)was performed in 12th hour after embolization.VDS was calculated according to coronary angiography.MCE scales were calculated.Results Among the eleven experimental dogs,VDS before embolization was 24.4±4.9 and that after embolization was 15.2±3.8.VDS after embolization was obviously lower than before embolization(P<0.05).VDS between LAD and LCX at the same stage was no difference;MCE scores after embolization were 7.6±2.4.VDS was negatively dependent with MCES after embolization(γ=-0.78,P<0.05).Conclusion As a newly quantitative index and keeping a closely correction with MCE,VDS can be used as a quantitative index to assess myocardial microperfusion in clinic.
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@#Objective To evaluate the feasibility and the value of video density scale (VDS) for assessing myocardial microperfusion.MethodsVDS and corrected TIMI frame counted (CTFC) were calculated and compared in 58 cases undergoing coronary catheter angiography.ResultsVDS of 58 cases was (22.5±5.8)and 95% confidence interval of normal myocardial microperfusion is(20.2,24.7).The CTFC was (21.1±4.5).It showed negative correlation between VDS and CTFC.ConclusionVDS is feasible to assess myocardial microperfusion quantificationally.The possibility of myocardial microperfusion dysfunction would be increased when VDS is lower than 20.