Improvement of preparing technique for Tongtian oral liquid / 国际药学研究杂志

Objective To improve the filtering technique and the addition methods of distillate for Tongtian oral liquid with a new type of filtering equipment. Methods The filter paper in the current filtering process was replaced with a combination of terylene filter cloth and pulvis talci. Distillate was added into the runny paste of preparation directly without using the solubilizer of Tween-80. Then the admixture was agitated sufficiently. After that, 10% NaOH was used to adjust the pH to 4.5-A.5, and the solution was added to 1200 L by water. At last, a clear preparation was obtained by using the above filtering equipment. Results Compared with the product made by the current method, the improved preparation was qualified and tasty. Conclusion The improved method is feasible, simple and economical. The product is tasty.

Research progress on evaluation methods of mouthfeel of oral drug delivery system / 中草药

Mouthfeel is an important part of preparation prescription study in oral drug delivery system. The results of traditional sensory evaluation are limited to individual differences of subjects, and own poor reproducibility. In this paper, some new technologies and evaluation methods were reviewed and commented, mainly including taste, adhesion, mucosal irritation, and grittiness, so as to provide methodology references for ODDS in traditional Chinese medicines and promote its progress.

Improvement of preparing technique for Tongtian oral liquid / 国际药学研究杂志

Objective To improve the filtering technique and the addition methods of distillate for Tongtian oral liquid with a new type of filtering equipment. Methods The filter paper in the current filtering process was replaced with a combination of terylene filter cloth and pulvis talci. Distillate was added into the runny paste of preparation directly without using the solubilizer of Tween-80. Then the admixture was agitated sufficiently. After that, 10% NaOH was used to adjust the pH to 4.5-6.5, and the solution was added to 1200 L by water. At last, a clear preparation was obtained by using the above filtering equipment. Results Compared with the product made by the current method,the improved preparation was qualified and tasty. Conclusion The improved method is feasible, simple and economical. The product is tasty.