RESUMO
Group of 41 cases and 26 cases of angina pectoris in CHD were treated with allicin tablet and Xiaoxintong respectively for comparison of their effect and changes in the indices of GMP-140, TXB2, 6-K-PGF1?, NO and hemorrheology were also observed. Results showed that the total effective rate of allicin tablet was 85. 4%, similar to Xiaoxintong. Allicin tablet can markedly lower the level of plasmal GMP - 140, TXB2. but increased the level of NO and substantially improve blood rheology, demonstrating that allicin tablet yield satisfactory effect on angina pectoris in CHD. The possible mechanism might lie on the activation of inhibition of platelets, prevention of thrombosis, dilatation of coronary arteries and peripheral vessels, improvement of hemorrheology.