RESUMO
Objective: To study the chemical constituents of the aerial parts of Salvia tiliifolia. Methods: The compounds were isolated and purified by various modern chromatographies, and their structures were identified by spectroscopic data. Results: Two compounds were isolated from the acetone extract of the aerial parts of S. tiliifolia, which were elucidated as 1-(furan-3-yl)-8- (2-oxo- 2,5-dihydrofuran-3-yl)-1,7,8,9-tetrahydronaphtho[1,2-c]furan-3,6-dione (1) and dugesin B (2). Conclusion: Compound 1 is a new clerodane diterpene with no cytotoxicity, named as 1-keto-tilifodiolide.
RESUMO
By means of preparative HPTLC and column chromatography over silica gel and Sephadex LH-20, fourteen diterpenoids were isolated and purified from the whole plants of Scutellaria galericulata. Based on the physico-chemical properties and spectral data, their structures were elucidated and identified as:scutebarbatine D(1), scutolide A(2), scutolide K(3), scutebata J(4), scutebata I(5), 6-O-acetylscutehenanine A(6), barbatin C(7), scutolide E(8), barbatine C(9), scutebarbatine Y(10), scutebarbatine B(11), scutestrigillosin A(12), scutebata O(13), scutolide B(14). Compounds 1-14 were isolated from S. galericulata for the first time.