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AIM: To investigate the efficacy of optimal pulse technology(OPT)in the treatment of demodex blepharitis and its influence on ocular surface function.METHODS: A retrospective study was conducted from February 2018 to October 2020. A total of 127 patients(254 eyes)with demodex blepharitis were assigned to the observation group and the control group according to the treatment method. The control group(63 patients, 126 eyes)were given conventional hot compress, eye cleansing and drug therapy. On this basis, the observation group(64 patients, 128 eyes)was treated with OPT. Both groups were given 6wk of continuous treatment. Demodex count, Marx's line scores, meibum character scores, ocular surface disease index(OSDI)scores, non-invasive tear break-up time(NIBUT), non-invasive tear meniscus height(NITMH)and lipid layer thickness(LLT)were compared between the two groups, and safety was evaluated.RESULTS: After 6wk of treatment, demodex count, Marx's line scores, meibum character scores and OSDI scores of the two groups decreased. NIBUT, NITMH and LLT increased. Meanwhile, demodex count, Marx's line scores, meibum character scores and OSDI scores of the observation group were significantly lower than those in the control group. NIBUT, NITMH and LLT were longer/larger than those in the control group(P<0.001). No obvious abnormality of intraocular pressure or conjunctival/corneal injury was observed in either group.CONCLUSION:OPT is effective and safe in the treatment of demodex blepharitis.
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@#AIM: To investigate the therapeutic effect of optimal pulse technology combined with tea tree essential oil paste in the treatment of Demodex blepharitis.<p>METHODS: Prospective clinical study. Totally 283 patients(566 eyes)with Demodex blepharitis were selected and randomly divided into three groups. Group A(94 cases, 188 eyes)was treated with optimal pulse technology, group B(96 cases, 192 eyes)was treated with tea tree essential oil paste, and group C(93 cases, 186 eyes)was treated with optimal pulse technology combined with tea tree essential oil paste. After 6wk of treatment, the number of Demodex, subjective symptom score, clinical sign score, tear film rupture time and corneal fluorescein staining were analyzed.<p>RESULTS: There was no significant difference in Demodex count, symptom score, sign score, tear film rupture time and corneal fluorescein staining among the three groups before treatment(<i>P</i>>0.05). After treatment, the number of Demodex among the three groups were significantly reduced(<i>P</i><0.05), and there were significant differences among group C, group A and group B(<i>P</i><0.05). The scores of subjective symptoms and signs of the three groups were significantly improved after treatment(<i>P</i><0.05), and the improvement of group C was more significant than that of group A and group B(<i>P</i><0.05). After treatment, tear break-up time of the group B not significantly improved, tear break-up time that of group C was significantly longer than that of groups A and B(<i>P</i><0.05); Fluorescent staining scores of three groups before and after treatment were significantly improved(<i>P</i><0.05). The statistical results of group C were better than those of groups A and B, but there was no difference among the three groups. No obvious complications occurred in all patients.<p>CONCLUSION: The effect of optimal pulse technology combined with tea tree essential oil in the treatment of acariasis blepharitis is significant, which is significantly better than that of single optimal pulse technology therapy and single use of tea tree essential oil.
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ObjectiveTo evaluate the effects of intense pulse light (OPT) on the facial pore widening of different parts.MethodsThirty six women with widened pores were enrolled,and treated by OPT for 6 times.All the cases were taken photos before and after treatment.The pores of cheek,nasal ala and nasal tip were graded by using the photographic scale,and the improvement after treatment compared with that before.ResultsThe cheek,nasal ala and nasal tip pores evidently diminished (P＜0.01).The improvement rate of cheek pores was higher than that of nasal ala and nasal tip (P＜0.01),but that between the latter two was not different (P＞0.05)).ConclusionsThe cheek pore widening diminishes more significantly than nasal ala and nasal tip treated with OPT.