Clinical Efficacy of Guizhi Shaoyao Zhimutang Combined with Fire Needling in Treatment of Periarthritis of Shoulder with Wind-cold-dampness Impediment Syndrome by Stimulating Pain Points and "Shoulder Three Acupoints" / 中国实验方剂学杂志

ObjectiveTo investigate the clinical efficacy of Guizhi Shaoyao Zhimutang （GZSYZM） combined with fire needling in the treatment of periarthritis of shoulder with wind-cold-dampness impediment syndrome by stimulating pain points and "shoulder three acupoints". MethodA total of 120 patients with periarthritis of shoulder with wind-cold-dampness impediment syndrome， admitted to Hainan General Hospital from August 2020 to August 2022， were randomly divided into two groups using a random number table. The control group （60 cases） received treatment with GZSYZM for two weeks， while the observation group （60 cases） received treatment with GZSYZM combined with fire needling at pain points and "shoulder three acupoints" for two weeks. The clinical efficacy， adverse reactions， shoulder pain intensity， shoulder joint function， and levels of calcitonin gene-related peptide （CGRP）， cyclooxygenase-2 （COX-2）， interleukin （IL）-2， and IL-17 before and after treatment were compared between the two groups. ResultThe total effective rate in the observation group was 88.33% （53/60）， significantly higher than 68.33% （41/60） of the control group （χ²=7.070， P<0.01）. Compared with the results before treatment， both groups showed significant reductions in pain rating index （PRI）， visual analog scale （VAS） scores， present pain intensity （PPI）， and Simplified McGill Pain Questionnaire （SF-MPQ） total scores， as well as serum levels of CGRP， COX-2， IL-2， and IL-17 after treatment （P<0.01）， and improved pain intensity， daily life abilities， joint mobility， muscle strength， and Constant-Murley score （P<0.01）. Compared with the control group after treatment， the observation group showed significantly reduced PRI， VAS score， PPI， SF-MPQ total score， as well as serum levels of CGRP， COX-2， IL-2， and IL-17 （P<0.01）， and increased pain intensity， daily life abilities， joint mobility， muscle strength， and Constant-Murley score （P<0.01）. There was no significant difference in the incidence of adverse reactions between the two groups. ConclusionGZSYZM combined with fire needling at pain points and "shoulder three acupoints" can effectively reduce the levels of serum inflammatory factors and pain mediators， alleviate pain， and improve shoulder joint function in patients with periarthritis of shoulder with wind-cold-dampness impediment syndrome.

Observing the Clinical Curative Effect of Using Intradermal Injection in the Clip Ridge Holes and Pain Points in Traces of Chest and Back Combined Oral Drug Cured Remaining Neuralgia after Herpes Zoster / 浙江中医药大学学报

[Objective]Using intradermal injection in the clip ridge holes and pain points combined oral drug cured remaining neuralgia after herpes zoster to observe the clinical curative effect.[Methods] 76 patients diagnosed with remaining neuralgia after herpes zoster in traces of chest and back were randomly divided into 40 cases of observation group and 36 cases of control group,the observation group was to use intradermal injection in the clip ridge holes and pain points combined oral drug,which was gabapentin cobalt and methyl amine pills.The control group was to use oral gabapentin cobalt and methyl amine pills.Observing two groups before and after the treatment with blurred vision score(VAS) and quality of sleep score(QS) was to comprehensively evaluate the efficacy of treatment.[Result] The VAS score during the period of the two groups after treatment was significantly decreased and the sleep quality score was significantly increased;After treatment,the VAS score of observation group was significantly lower than the VAS score of control group in the same period,but the sleep quality score of observation group was significantly higher than the sleep quality score of control group in the same period.The observation group was significantly higher than the control group in clinical effectiveness.[Conclusion] It had good clinical effect to use intradermal injection in the clip ridge holes and pain points combined oral drug to cure remaining neuralgia after herpes zoster in traces of chest and back.It could quickly relieve pain symptoms and improve sleep quality,so it was a kind of effective method for the treatment of remaining neuralgia after herpes zoster.