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1.
Chinese Journal of Clinical Pharmacology and Therapeutics ; (12): 1340-1346, 2022.
Artigo em Chinês | WPRIM | ID: wpr-1014739

RESUMO

AIM: To investigate the effects of different doses of degmedetomidine on stress and postoperative sleep in patients with coronare heart disease (CHD). METHODS: Sigte patients with coronare heart disease undergoing endoscopic abdominal surgere were randomle divided into three groups (n d 20): low-dose group (D1), high-dose degmedetomidine group (D2) and control group (C) In groups D1 and D2, a loading dose of degmedetomidine (0.5 μg/kg) was injected with intravenous pump for 10 min, followed be the maintain dose of degmedetomidine 0.2 and 0.6 μg·kg

2.
Chinese Journal of Clinical Pharmacology and Therapeutics ; (12): 1322-1332, 2022.
Artigo em Chinês | WPRIM | ID: wpr-1014737

RESUMO

Noninvasive neuromodulation technique is a non-invasive, safe and convenient research and treatment method, which is mainly regulated by electrical stimulation and magnetic stimulation. In recent years, it has been more and more used in the research and treatment of brain function. It has been confirmed in the regulation of cognitive impairment, depression, anxiety, delirium and insomnia in patients with stroke. Clinical departments such as neurology, rehabilitation department, pain department and other disciplines have widely used this technique of non-invasive neural regulation, but its application in the perioperative period is less, especially for postoperative sleep disorders in patients with general anesthesia. Postoperative sleep disorder is a common and easily neglected complication, which is often manifested as postoperative sleep structure disorder, sleep quality decline, sleep is obviously shortened, and the sleep function of patients with general anesthesia is more likely to be affected. Postoperative sleep disorder includes many influencing factors before, during and after operation, affecting the whole perioperative period and even a few years after discharge.

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