Effect of Polygona-polysaccharose on Expression of RAGE mRNA in Brain of Diabetic Rats / 中国药房

OBJECTIVE:To study the regulative function of polygona-polysaccharose on the expression of RAGE mRNA in diabetic rats’brain.METHODS:Diabetic rat model was made by intraperitoneal injection of streptozotocin.RT-PCR method was used to examine the expression of RAGE mRNA in rats’brain.RESULTS:The expression of RAGE mRNA in brain tissue of diabetic rats was increased.The value of RAGE/?-actin in diabetic rats was significantly higher than that in the control group(P