Clinical efficacy and action mechanism of mild moxibustion combined with salt-separated moxibustion for gastrointestinal response in breast-cancer chemotherapy patients / 中国针灸

OBJECTIVE@#To evaluate the clinical efficacy and partial action mechanism of mild moxibustion combined with salt-separated moxibustion for gastrointestinal discomfort caused by chemotherapy for breast cancer.@*METHODS@#A total of 48 patients were randomly divided into an observation group and a control group, 24 cases in each group. The patients in the control group were treated with intravenous infusion of tropisetron hydrochloride (5 mg), once a day for three days; the patients in the observation group were additionally treated with mild moxibustion at Zusanli (ST 36), Zhongwan (CV 12), Guanyuan (CV 4), Qihai (CV 6) and salt-separated moxibustion at Shenque (CV 8), 15 min per treatment, once a day for 7 days. Before treatment and on the 7th day of chemotherapy, the levels of pepsinogenⅠ(PGⅠ), pepsinogenⅡ (PGⅡ), the ratio of PGⅠto PGⅡ (PGR) and gastrin 17 (G-17) in serum were measured. Before treatment and on the 3rd, 5th, 7th day of chemotherapy, the gastrointestinal reactions (nausea, vomiting, constipation, diarrhea) were compared between the two groups.@*RESULTS@#On the 7th day of chemotherapy, the serum levels of PGⅠ, PGⅡand G-17 in the observation group were lower than those in the control group (0.05). The total scores of nausea, vomiting and constipation during chemotherapy in the observation group were significantly lower than those in the control group (all <0.05).@*CONCLUSION@#The mild moxibustion combined with salt-separated moxibustion could effectively improve the symptoms of nausea, vomiting and constipation caused by chemotherapy in patients with breast cancer, and its mechanism may be related to the down-regulation of the levels of PGⅠ, PGⅡ and G-17 in serum.

Preventive Effects of Umbilical Paste and Salt-separated Moxibustion on Adverse Reactions of Digestive Tract in the Patients with Non-hodgkin's Lymphoma / 中国药师

Objective: To observe the clinical effect of umbilical paste and salt-separated moxibustion on the adverse reactions of digestive tract in the patients with non-hodgkin's lymphoma(NHL). Methods: Totally 60 patients with NHL were divided into two groups according to the order of admission. The control group was treated with the conventional nursing, and the observation group was treated with umbilical paste and salt-separated moxibustion. The preventive effect on constipation, nausea, vomiting and loss of appe-tite were compared between the groups. Results: The incidence of constipation, nausea, vomiting and anorexia on the 3nd and 5th day after the chemotherapy was significantly lower than that in the control group(P<0. 05). Conclusion: The preventive effects of umbili-cal paste combined with umbilical and salt-separated moxibustion on the gastrointestinal adverse reactions after chemotherapy for non-Hodgkin's lymphoma are better than those of the routine nursing, and the method is simple and easy to implement and popularize.