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1.
Chinese Journal of Biochemical Pharmaceutics ; (6): 385-387, 2017.
Artigo em Chinês | WPRIM | ID: wpr-613852

RESUMO

Objective To study the efficacy and safety of mifepristone combined with the end of pregnancy in the treatment of uterine scar pregnancy.Methods50 cases of the experimental group in our hospital from February 2014 to December 2016 during the termination of pregnancy uterine scar pregnancy in this study in the research process, no scar uterine pregnancy were 50 as the control group in the process of research.The experimental group and the control group patients were given mifepristone treatment, oral use, patients in the drug treatment of third days should be carried out taking the drug misoprostol experiment, fasting medication, placed in the posterior fornix of vagina.Comparative analysis of the experimental group and the control group of patients with treatment effects and adverse reactions.ResultsAfter a period of treatment, the experimental group and the control group, the time of vaginal discharge and the amount of vaginal bleeding and uterine contractions were no significant difference in the time, not statistically significant.The experimental group of 50 patients, the number of effective treatment for 47 cases, the effective rate was 94%.The control group of 50 patients, the number of effective treatment for the treatment of 48 cases, the effective rate was 96%.As a result, there was no significant difference between the experimental group and the control group in the treatment efficacy, which was not statistically significant (P>0.05).The incidence of adverse reactions in the experimental group was 10%, and the incidence of adverse reactions in the control group was 8%.As a result, there was no significant difference between the experimental group and the control group in the incidence of adverse reactions, which was not statistically significant.ConclusionMifepristone combined with carboprost suppository in the treatment of uterine scar end effect is good, high treatment efficiency, reduce the incidence of adverse reaction, high safety, can reduce the patients caused by trauma to a great extent, is further applied in clinical significance.

2.
Chinese Journal of Biochemical Pharmaceutics ; (6): 212-214, 2017.
Artigo em Chinês | WPRIM | ID: wpr-612752

RESUMO

Objective To evaluate the efficacy of mifepristone combined with cardiopulmonary suppository combined with psychological intervention in the termination of scar uterine pregnancy.Methods60 cases of maternal women with scarring uterine pregnancy during our period from March 2015 to December 2016 were selected as the experimental group in the course of this study.Maternal 60 with no scarring uterine pregnancy was selected as the control in this study group.Related medical staff need to strengthen communication with patients, understand the negative thoughts of the patient's heart, use their expertise to solve doubts for patients, eliminate anxiety and anxiety, improve patient treatment compliance, the establishment of patient treatment confidence;experimental group and control group of patients Were treated with mifepristone, oral use, the patient in the third day of drug treatment should be tested card pregnant suppository to take, the drug selected fasting medication, placed in the vagina on the dome.To compare the therapeutic effect of the experimental group and the control group and the adverse reaction.ResultsAfter treatment, 60 cases in the experimental group, the total effective number of cases in the treatment of patients with a total of 55 cases, the number of invalid cases in the treatment of patients, the effective rate was 91.7%.The control group of 60 patients, the total effective number of cases for the treatment of 48 cases, the number of invalid cases in the treatment of patients, the effective rate was 80.0%.The results showed that there was significant difference between the experimental group and the control group (P<0.05).After treatment, there was no significant difference in the time of vaginal discharge, the amount of vaginal bleeding and the time of uterine contraction.In the control group, there were 8 cases of adverse reactions, the probability was 13.3%, in the experimental group, the number of cases of adverse reactions occurred in the number of cases, the probability was 6.7%.There was significant difference between the experimental group and the control group in the incidence of adverse reactions(P<0.05).ConclusionMifepristone combined with carboprost suppository in the treatment of psychological intervention combined with the termination of good uterine scar effect, low incidence rate of adverse reaction, high treatment efficiency, high safety, with further clinical promotion and application significance.

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