RESUMO
Gastroesophageal reflux disease (GERD) can cause not only esophageal symptoms, but also extraesophageal symptoms such as globus pharyngis. Here, we describe a case of globus pharyngis in GERD successfully treated with seinetsuhoketsuto. A 72-year-old female began to have tingling in her pharyngolarynx in February 20XX. Otolaryngologist did not point out abnormal findings. However, reflux esophagitis was detected by upper gastrointestinal endoscopy. Although treatment with rabeprazole relieved the tingling, she experienced a relapse in September 20XX and visited our clinic in November. We prescribed seinetsuhoketsuto because she exhibited numerous blood deficiency-related symptoms including dryness of the skin and eyes, shallow sleep, coldness in the feet, etc. The tingling then decreased rapidly and disappeared in two months. In addition, dryness of the skin and eyes and her sleep also improved markedly. Seinetsuhoketsuto has been regarded as a medication for inflammation in the mouth such as oral ulcers and erosions. However, this case indicated that seinetsuhoketsuto could also be utilized to treat symptoms in the pharyngolarynx due to GERD.
RESUMO
It is reported that the administration of Seinetsu-hoketsu-to has been effective in four cases of recurrent aphthous stomatitis. The literature states that Seinetsu-hoketsu-to is indicated for “blood deficiency and the combination of pathogenic dryness and heat in blood which causes ulceration or erosion with scaling pain in the tongue and oral mucosa, and its healing is often prolonged.” All four cases the patients are female. Their aphthous stomatitis is often exacerbated during pregnancy, childbirth, and/or each menstruation. In one case aphthous stomatitis reoccurred after the remission of general symptoms due to high fever and inflammation in the acute phase of Beçhet disease. The conclusion is that Seinetsu-hoketsu-to would be useful to patients with recurrent aphthous stomatitis in conditions where blood deficiency is worsening.