Analysis on Composition Mechanism of Qingfei Paidu Decoction from Pathogenesis of Cold Pestilence of COVID-19 / 中国实验方剂学杂志

Qingfei Paidu decoction has a remarkable clinical effect, which has been recommended by the Diagnosis and Treatment Plan of Novel Coronavirus Pneumonia (Trial Sixth Edition) of the National Health Commission and National Administration of Traditional Chinese Medicine. In this paper, the authors intend to explore the pathogenesis of cold pestilence of coronavirus disease-2019 (COVID-19) and composition mechanism of Qingfei Paidu decoction, and believe that this formula can be used to relieve internal and external pressure and regulate triple energizer with the functions of promoting lung Qi, dispelling evil and detoxification, moistening and dampening, and purging heat by removing water. This formula is suitable for the pathogenesis of COVID-19, including cold, dryness and dampness, and can effectively treat symptoms. Therefore, it should be widely used throughout the country to contain the spread of the epidemic.

A Case of Bullous Pemphigoid Completely Remitted with Formulation of Seihijoshitsuinkagen (Qing Pi Chu Shi Yin Hua Cai) / 日本東洋医学雑誌

We report one case of bullous pemphigoid that did not respond to the standard western medical treatment with topical and oral steroid therapy. This case achieved complete remission after the application of Yizongjinjion seihijoshitsuinkagen (Yizongjinjion Qing Pi Chu Shi Yin Hua Cai), a spleen-dampness-eliminating beverage. The patient was a 78-year old female who had soy bean or 5 mm to 25 mm sized blisters covering a wide area of her back since two years ago. She had visited a neighborhood physician who diagnosed her with bullous pemphigoid and initiated the standard treatment. Although some improvements were observed after the start of western medical treatment, her symptoms eventually grew worse. Therefore, she visited our clinic and requested the traditional Chinese treatment. We diagnosed her skin blisters as the heart-fire spleen-dampness type of bullous pemphigoid using the four diagnostic examinations, and treated her with the modulated spleen-dampness-eliminating beverage which resulted in a complete remission within 10 months. Taken together, our results suggest that the modulated spleen-dampness-eliminating beverage (Yizongjinjion seihijoshitsuinkagen) is effective for the treatment of the heart-fire spleen-dampness type of bullous pemphigoid.