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Chinese Journal of Biochemical Pharmaceutics ; (6): 143-146, 2014.
Artigo em Chinês | WPRIM | ID: wpr-452674

RESUMO

Objective To observe the effect of concomitant low-frequency neural muscular electric stimulation (NMES)and alprostadil on the motion and balance in paralysis patients with acute ischemic infarction (AIS ).Methods 82 cases with AIS admitted in Ningjin Country People's Hospital,from August 2008 to August 2013 were divided into three groups.Conventional treatment group (n =26)were received conventional rehabilitation,NMES control group (n=30)were received conventional rehabilitation+NEMS(4 times a day,every 15 min)and observation group were received conventional rehabilitation+NEMS(4 times a day,every 15 min)+alprostadil (2 mL+10 mL normal saline intravenously slowly,1 times a day),all patients were treated for three weeks.Ankle dorsi-flexors tension were evaluated by comprehensive spasm scale (CSS).The ankle dorsiflexion and plantar flexor of top isometric voluntary contraction (TIVC)were tested by surface electromyography(sEMG).Quantitative detection of“integrator”EMG and the cooperative shrinkage rate of muscles were detected to evaluate patients'balance level and walking ability.Results Each index score of patients in three groups before treatment had no difference.3 weeks after treatment,the ankle plantar flexion muscle spasm in patients of observation group were aggravating,and CSS had increased highest,there were significant differences with other two groups(P<0.05).After treatment, the ankle back of MIVC pretibial muscle were increased in all three groups,which were respectively 10 ±6 nm,6 ±4 nm,5 ±4 nm.When ankle dorsiflexion,co-contraction rate were significantly lower,respectively at (9 ±0.5)%,(28 ±0.27)%,(27 ±0.19)%.3 weeks treatment,patients in observation group walk to restore balance and walking force time was 3~4 d ahead than two control groups.Conclusion Low frequency electric stimulation combined alprostadil can improve the movement function in AIS hemiplegia patients.

2.
Chinese Traditional Patent Medicine ; (12)1992.
Artigo em Chinês | WPRIM | ID: wpr-681841

RESUMO

Objective: To investigate the new processing method of Arisaema Amurense Maxim. Methods: Referring to hot and and tingle taste, we have screened out the best condition in processing Arisaema Amurense Maxim. by testing in orthogonal designs, and compared stimulation, extractives and UV of different samples. Results: The new processing method can save half slum according to Ch P. the stimulation of the two samples processed by Ch P & by new method is similar; the water soluble and ethanol soluble extractives and UV of processed samples by new method is better than that by Pharmacopoeia of PR. China. Conclusion: The new method screened out by testing in orthogonal design, can not only eliminate hot and tingle taste, reduce the lose of effective component, but also save a lot of slum.

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