RESUMO
GU Wei-chao has been a TCM doctor for over 50 years, with enriched learning and practicing experience. He has experience in ZHANG Xi-chun's academic thoughts, especially used Zhang’s theory of sinking qi in his medical practice. He added Rhodiolae Crenulatae Radix et Rhizoma, Agrimoniae Herba, Taxilli Herba, Nardostachyos Radix et Rhizoma, Corni Fructus, and Glycyrrhizae Radix et Rhizoma Praeparata cum Melle to Shengxian Decoction to make modified Shengxian Decoction, in order to strengthen the efficacy of invigorating qi and ascending qi collapse, cultivating the essence and notifying kidney, reinforcing heart and astringing qi, and inducing resuscitation and allaying tiredness. This article introduced GU Wei-chao using Zhang’s theory of sinking qi to strengthen the efficacy of modified Shengxian Decoction for chronic diseases by combining two medical cases of unexplained diabetes and myasthenia gravis. Therefore, this article believed that invigorating qi and ascending qi collapse method has advantages in treating chronic diseases, with worth of clinical promotion and application.