Aspectos actuales del carcinoma bien diferenciado de tiroides / Present-day aspects of Carcinoma well told apart of the thyroid

El carcinoma de tiroides ha aumentado su incidencia en los últimos años. Su diagnóstico rápido y consiguiente tratamiento son necesarios para una mayor sobrevida del paciente. El ultrasonido aun es la prueba diagnóstica de mayor utilidad. La biopsia por aspiración por aguja fina guiada por ultrasonido ha permitido disminuir los falsos negativos, así como incrementar la eficacia y sensibilidad de esta prueba. La cirugía es la mejor opción curativa que tiene la enfermedad, su extensión es aun controversial. El tratamiento en equipo multidisciplinario ha hecho avanzar en ello y optimizar el tiempo de diagnóstico, los métodos, así como el tipo de tratamiento a utilizar(AU)

Thyroidal carcinoma incidence has increased over recent years. Quick diagnosis and arranged treatment are necessary for the patient’s improved survival. Ultrasound continues to be the diagnostic test of greater usefulness. Ultrasound-guided aspiration biopsy has decreases the false-negative results, as well as this test’s efficacy and sensibility have increased. Surgery is the best healing choice against the disease, though its extension is even controversial. Treatment by multidisciplinary teams has prospered it optimized diagnosis time and methods, as well as the type of treatment to use(AU)

Spontaneous bisphosphonate-related osteonecrosis of the left hemi-mandible: Similarities with phossy jaw.

Intravenous bisphosphonates (BP) play a key role in the treatment of bone metastases. As a long-term side effects BP, a form of avascular osteonecrosis of the jaw has been reported. Although, invasive oral local procedures are often present in clinical history of patients suffering from bisphosphonates-related osteonecrosis of the jaws (BRONJ), about up to 50% of BRONJ are spontaneous. We report a case of a 68-year-old female with a spontaneous wide bone sequestration of the left mandibular body onset after infusion of zoledronic acid for 18 cycles for osseous metastasis due to metastatic anaplastic thyroidal carcinoma. Surprisingly the clinical aspects of the patient initially reminded us of the famous pathology described in 1899 called phossy jaw. This case is remarkable not only for the spontaneity of the osteonecrosis, but, above all, for the clinical similarity with cases of phossy jaw, described for the first time in the literature, thereby suggesting a potential common pathogenesis.